Motif ID: Nfe2l1_Mafg
Z-value: 1.254
Transcription factors associated with Nfe2l1_Mafg:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Mafg | ENSMUSG00000051510.7 | Mafg |
Mafg | ENSMUSG00000053906.4 | Mafg |
Nfe2l1 | ENSMUSG00000038615.11 | Nfe2l1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Mafg | mm10_v2_chr11_-_120630516_120630636 | -0.72 | 3.4e-05 | Click! |
Nfe2l1 | mm10_v2_chr11_-_96824008_96824159 | 0.44 | 2.3e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 11.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.6 | 1.9 | GO:0021759 | globus pallidus development(GO:0021759) |
0.6 | 3.2 | GO:0097475 | motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476) |
0.6 | 1.8 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274) |
0.5 | 1.6 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.5 | 4.1 | GO:0060594 | mammary gland specification(GO:0060594) |
0.3 | 2.5 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
0.3 | 1.8 | GO:0051461 | regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.3 | 1.0 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
0.2 | 0.7 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.2 | 1.4 | GO:0060242 | contact inhibition(GO:0060242) |
0.2 | 0.7 | GO:0019085 | early viral transcription(GO:0019085) |
0.2 | 0.6 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.1 | 0.6 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.1 | 0.4 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
0.1 | 0.6 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.1 | 2.3 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.1 | 0.4 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.1 | 0.6 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
0.1 | 1.1 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 0.3 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
0.1 | 0.5 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.1 | 1.1 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.1 | 0.9 | GO:0060539 | diaphragm development(GO:0060539) |
0.1 | 2.4 | GO:0090022 | regulation of neutrophil chemotaxis(GO:0090022) |
0.1 | 0.6 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.1 | 0.5 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.1 | 1.1 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.1 | 0.3 | GO:0090164 | protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164) |
0.1 | 1.6 | GO:0000154 | rRNA modification(GO:0000154) |
0.1 | 0.3 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
0.1 | 0.2 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.1 | 0.2 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.1 | 1.1 | GO:0080111 | DNA demethylation(GO:0080111) |
0.1 | 0.7 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.1 | 0.5 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
0.1 | 0.2 | GO:2000832 | cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
0.1 | 0.6 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.1 | 0.3 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.1 | 0.3 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 1.0 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.1 | 0.3 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.1 | 0.3 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.1 | 0.2 | GO:0030210 | heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014) |
0.1 | 1.1 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.1 | 1.0 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
0.0 | 0.2 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.0 | 0.2 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
0.0 | 0.5 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.0 | 0.5 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.0 | 0.1 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) aggrephagy(GO:0035973) |
0.0 | 0.5 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
0.0 | 0.2 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
0.0 | 0.3 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
0.0 | 0.2 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) |
0.0 | 0.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.1 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.0 | 0.5 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.2 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.0 | 0.4 | GO:0048240 | sperm capacitation(GO:0048240) |
0.0 | 1.8 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.0 | 0.3 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.0 | 0.1 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
0.0 | 0.4 | GO:0006625 | protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
0.0 | 0.4 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
0.0 | 0.4 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.0 | 0.4 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.0 | 0.1 | GO:0034143 | regulation of toll-like receptor 4 signaling pathway(GO:0034143) |
0.0 | 0.9 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.1 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.0 | 0.3 | GO:0043252 | oligopeptide transport(GO:0006857) sodium-independent organic anion transport(GO:0043252) |
0.0 | 1.8 | GO:0000077 | DNA damage checkpoint(GO:0000077) |
0.0 | 0.4 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.0 | 0.5 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
0.0 | 1.4 | GO:0043966 | histone H3 acetylation(GO:0043966) |
0.0 | 0.5 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.1 | GO:1903069 | regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) |
0.0 | 2.4 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.0 | 0.2 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
0.0 | 1.2 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 1.7 | GO:0042472 | inner ear morphogenesis(GO:0042472) |
0.0 | 0.8 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
0.0 | 0.1 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.0 | 0.2 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
0.0 | 0.7 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
0.0 | 0.0 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.0 | 0.1 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.0 | 0.5 | GO:0007030 | Golgi organization(GO:0007030) |
0.0 | 0.4 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
0.0 | 0.5 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 0.8 | GO:0031110 | regulation of microtubule polymerization or depolymerization(GO:0031110) |
0.0 | 0.4 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.4 | GO:0008623 | CHRAC(GO:0008623) |
0.2 | 1.6 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.2 | 0.6 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.2 | 0.7 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.2 | 0.5 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
0.1 | 0.4 | GO:0036128 | CatSper complex(GO:0036128) |
0.1 | 0.6 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.1 | 0.9 | GO:0070652 | HAUS complex(GO:0070652) |
0.1 | 0.4 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.1 | 0.6 | GO:0071817 | MMXD complex(GO:0071817) |
0.1 | 0.3 | GO:0035061 | interchromatin granule(GO:0035061) |
0.1 | 0.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 0.7 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
0.1 | 0.6 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
0.1 | 0.9 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.1 | 0.8 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.1 | 1.1 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.1 | 0.8 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.0 | 0.3 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696) |
0.0 | 0.6 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.4 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 0.6 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 2.0 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.4 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.5 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.0 | 0.3 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.0 | 0.7 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 1.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.2 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 2.4 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
0.0 | 0.5 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 6.2 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.1 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 1.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 1.0 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.6 | GO:0000502 | proteasome complex(GO:0000502) |
0.0 | 1.1 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.7 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.1 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.4 | 2.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.3 | 0.8 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.2 | 1.0 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.2 | 1.1 | GO:0005047 | signal recognition particle binding(GO:0005047) |
0.2 | 1.0 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.2 | 1.5 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.2 | 1.9 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.1 | 0.7 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.1 | 2.9 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.1 | 2.0 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.1 | 1.6 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.1 | 2.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.1 | 0.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 3.2 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.1 | 0.9 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.1 | 0.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 0.4 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.1 | 1.2 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.1 | 1.2 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.1 | 0.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.6 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
0.1 | 2.6 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.1 | 1.7 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 0.2 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
0.1 | 1.3 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.1 | 0.6 | GO:0034711 | inhibin binding(GO:0034711) |
0.1 | 0.2 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.1 | 12.4 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.1 | 0.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.1 | 0.6 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 0.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.0 | 0.1 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
0.0 | 0.3 | GO:0031419 | cobalamin binding(GO:0031419) |
0.0 | 0.6 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.0 | 2.0 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.2 | GO:0008808 | cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) |
0.0 | 0.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 0.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.3 | GO:0043559 | insulin binding(GO:0043559) |
0.0 | 0.4 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 1.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.1 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
0.0 | 1.1 | GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814) |
0.0 | 8.2 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 1.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.0 | 0.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.0 | 0.5 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.5 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 0.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 1.2 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 0.3 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.0 | 0.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.1 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.0 | 0.2 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.0 | 0.4 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.8 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) |
0.0 | 0.4 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.0 | 0.1 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) |
0.0 | 1.0 | GO:0019843 | rRNA binding(GO:0019843) |
0.0 | 0.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.1 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.0 | 0.1 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.0 | 0.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |