Motif ID: Nfia

Z-value: 2.684


Transcription factors associated with Nfia:

Gene SymbolEntrez IDGene Name
Nfia ENSMUSG00000028565.12 Nfia

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfiamm10_v2_chr4_+_97777780_977778340.671.9e-04Click!


Activity profile for motif Nfia.

activity profile for motif Nfia


Sorted Z-values histogram for motif Nfia

Sorted Z-values for motif Nfia



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfia

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_130936172 19.336 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr11_+_78324200 14.960 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chrX_-_141874870 14.924 ENSMUST00000182079.1
 Gm15294
predicted gene 15294
chr5_+_66968416 12.868 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr6_+_141524379 12.781 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr15_-_81499548 12.544 ENSMUST00000172270.1
 Gm5218
predicted gene 5218
chr4_-_64046925 12.149 ENSMUST00000107377.3
 Tnc
tenascin C
chr14_+_11227511 11.817 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr19_+_5740885 11.250 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr4_+_48045144 10.804 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr19_-_5457397 10.598 ENSMUST00000179549.1
 Ccdc85b
coiled-coil domain containing 85B
chr4_+_105790534 10.538 ENSMUST00000185012.1
 Gm12728
predicted gene 12728
chr5_+_66968559 10.328 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr7_-_46179929 10.086 ENSMUST00000033123.6
 Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr12_-_4689926 9.817 ENSMUST00000080062.6
 Gm17541
predicted gene, 17541
chr17_-_46440099 9.504 ENSMUST00000166852.1
 Gm5093
predicted gene 5093
chr11_+_67586520 9.318 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr6_-_126166726 8.960 ENSMUST00000112244.2
ENSMUST00000050484.7
 Ntf3

neurotrophin 3

chr7_-_97417730 8.342 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr1_+_185454803 8.226 ENSMUST00000061093.6
 Slc30a10
solute carrier family 30, member 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 357 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 37.2 GO:0031032 actomyosin structure organization(GO:0031032)
3.2 19.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.5 15.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.8 14.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
1.9 13.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.1 12.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 12.4 GO:0002181 cytoplasmic translation(GO:0002181)
3.0 12.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
3.8 11.2 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
3.6 10.8 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.7 10.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 10.1 GO:0010043 response to zinc ion(GO:0010043)
2.0 9.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 9.6 GO:0051017 actin filament bundle assembly(GO:0051017)
1.8 9.0 GO:0007403 glial cell fate determination(GO:0007403)
0.2 9.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 8.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.5 8.4 GO:0045792 negative regulation of cell size(GO:0045792)
2.8 8.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.4 8.2 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 143 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 38.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 27.4 GO:0031012 extracellular matrix(GO:0031012)
0.3 21.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 20.7 GO:0000786 nucleosome(GO:0000786)
0.0 14.7 GO:0043005 neuron projection(GO:0043005)
3.5 14.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 12.4 GO:0030175 filopodium(GO:0030175)
0.1 11.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 11.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 10.6 GO:0001726 ruffle(GO:0001726)
0.3 10.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 9.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 9.8 GO:0097440 apical dendrite(GO:0097440)
0.5 8.5 GO:0005614 interstitial matrix(GO:0005614)
0.8 8.4 GO:0031931 TORC1 complex(GO:0031931)
0.2 8.4 GO:0031201 SNARE complex(GO:0031201)
0.0 8.2 GO:0000139 Golgi membrane(GO:0000139)
0.1 7.9 GO:0030315 T-tubule(GO:0030315)
0.1 7.7 GO:0030426 growth cone(GO:0030426)
2.5 7.6 GO:0043512 inhibin A complex(GO:0043512)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 235 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 30.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 28.8 GO:0003779 actin binding(GO:0003779)
0.3 21.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 21.6 GO:0044325 ion channel binding(GO:0044325)
0.9 20.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
2.5 15.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
4.6 13.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 13.2 GO:0005178 integrin binding(GO:0005178)
3.2 12.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.0 12.1 GO:0045545 syndecan binding(GO:0045545)
0.5 11.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.7 11.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 10.8 GO:0005518 collagen binding(GO:0005518)
0.4 10.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.5 9.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.8 9.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
2.8 8.3 GO:0098809 nitrite reductase activity(GO:0098809)
2.0 8.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.7 7.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.2 7.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)