Motif ID: Nfic_Nfib
Z-value: 1.754
Transcription factors associated with Nfic_Nfib:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nfib | ENSMUSG00000008575.11 | Nfib |
| Nfic | ENSMUSG00000055053.11 | Nfic |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nfic | mm10_v2_chr10_-_81430966_81431039 | 0.82 | 3.4e-07 | Click! |
| Nfib | mm10_v2_chr4_-_82705735_82705754 | 0.64 | 4.5e-04 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 15.5 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 2.1 | 12.6 | GO:1902847 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) |
| 1.9 | 15.1 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 1.8 | 9.1 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 1.7 | 17.4 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 1.5 | 7.4 | GO:1900085 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) |
| 1.3 | 4.0 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
| 1.2 | 8.5 | GO:0015840 | urea transport(GO:0015840) urea transmembrane transport(GO:0071918) |
| 1.1 | 6.5 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
| 1.1 | 6.4 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 1.0 | 2.9 | GO:0043465 | regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003) |
| 0.9 | 5.6 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
| 0.9 | 8.3 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
| 0.9 | 2.6 | GO:0051933 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
| 0.8 | 1.6 | GO:1901204 | regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) |
| 0.8 | 5.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.7 | 1.5 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 0.7 | 4.1 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
| 0.6 | 1.9 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.6 | 2.2 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.5 | 3.8 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.5 | 2.1 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.5 | 2.6 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 0.5 | 1.5 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
| 0.5 | 1.5 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.5 | 2.0 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.5 | 1.9 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.5 | 2.3 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.4 | 2.2 | GO:1902947 | regulation of tau-protein kinase activity(GO:1902947) |
| 0.4 | 4.3 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.4 | 4.2 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.4 | 2.8 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.4 | 2.0 | GO:0042167 | heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.4 | 1.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.4 | 1.1 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.4 | 3.7 | GO:0006691 | leukotriene metabolic process(GO:0006691) |
| 0.4 | 1.1 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) |
| 0.4 | 1.1 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.3 | 1.3 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 0.3 | 3.7 | GO:0010748 | negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.3 | 1.5 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.3 | 1.5 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.3 | 0.6 | GO:0072008 | glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
| 0.3 | 4.6 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.2 | 6.5 | GO:0033622 | integrin activation(GO:0033622) |
| 0.2 | 3.4 | GO:0031269 | pseudopodium assembly(GO:0031269) |
| 0.2 | 0.7 | GO:0009247 | glycolipid biosynthetic process(GO:0009247) |
| 0.2 | 2.7 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.2 | 0.7 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.2 | 1.1 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.2 | 0.7 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.2 | 0.9 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.2 | 1.2 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
| 0.2 | 2.0 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.2 | 0.6 | GO:0003032 | detection of oxygen(GO:0003032) |
| 0.2 | 1.8 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.2 | 1.1 | GO:0071455 | cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455) |
| 0.2 | 0.2 | GO:0070508 | sterol import(GO:0035376) regulation of cholesterol import(GO:0060620) cholesterol import(GO:0070508) regulation of sterol import(GO:2000909) |
| 0.2 | 3.0 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.2 | 1.0 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.2 | 0.7 | GO:0010046 | arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046) |
| 0.1 | 4.3 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
| 0.1 | 0.6 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.1 | 0.3 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 0.1 | 3.5 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 0.6 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
| 0.1 | 1.6 | GO:0051447 | negative regulation of meiotic cell cycle(GO:0051447) |
| 0.1 | 0.3 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 0.1 | 0.9 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.1 | 0.7 | GO:0032782 | bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.1 | 1.0 | GO:0051409 | response to nitrosative stress(GO:0051409) |
| 0.1 | 0.8 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.1 | 0.3 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
| 0.1 | 2.1 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
| 0.1 | 0.5 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.1 | 0.5 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.1 | 0.7 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.1 | 0.9 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.1 | 0.4 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.1 | 1.1 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
| 0.1 | 0.4 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.1 | 0.5 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.1 | 0.5 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.1 | 0.6 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 4.2 | GO:0048678 | response to axon injury(GO:0048678) |
| 0.1 | 0.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.1 | 0.2 | GO:0003195 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.1 | 2.1 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 0.8 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 0.5 | GO:2000598 | regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599) |
| 0.1 | 0.9 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
| 0.1 | 3.7 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.1 | 4.2 | GO:0048747 | muscle fiber development(GO:0048747) |
| 0.1 | 0.6 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.1 | 0.2 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.1 | 2.1 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 1.0 | GO:0021681 | cerebellar granular layer development(GO:0021681) |
| 0.1 | 0.6 | GO:0035336 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) |
| 0.1 | 0.5 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.1 | 0.9 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
| 0.1 | 1.5 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.1 | 0.2 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449) |
| 0.1 | 0.2 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 0.1 | 1.5 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
| 0.1 | 2.1 | GO:0019915 | lipid storage(GO:0019915) |
| 0.0 | 0.3 | GO:0009169 | purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) |
| 0.0 | 0.2 | GO:0060591 | chondroblast differentiation(GO:0060591) |
| 0.0 | 0.9 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 3.9 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 0.6 | GO:0021954 | central nervous system neuron development(GO:0021954) |
| 0.0 | 0.4 | GO:0006206 | pyrimidine nucleobase metabolic process(GO:0006206) |
| 0.0 | 1.1 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.7 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.0 | 3.7 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.0 | 0.3 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.0 | 0.1 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 0.0 | 0.1 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.0 | 0.1 | GO:0002238 | response to molecule of fungal origin(GO:0002238) |
| 0.0 | 0.5 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.0 | 0.7 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.0 | 0.3 | GO:2000194 | regulation of female gonad development(GO:2000194) |
| 0.0 | 0.2 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
| 0.0 | 0.7 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.0 | 0.7 | GO:0046185 | aldehyde catabolic process(GO:0046185) |
| 0.0 | 0.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.1 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.0 | 0.5 | GO:0032094 | response to food(GO:0032094) |
| 0.0 | 1.0 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.0 | 0.2 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.0 | 0.4 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
| 0.0 | 0.4 | GO:0019884 | antigen processing and presentation of exogenous antigen(GO:0019884) |
| 0.0 | 0.7 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 0.0 | 0.6 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 1.5 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.1 | GO:1900110 | single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) negative regulation of histone H3-K9 dimethylation(GO:1900110) |
| 0.0 | 0.7 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.4 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.0 | 0.9 | GO:0051438 | regulation of ubiquitin-protein transferase activity(GO:0051438) |
| 0.0 | 0.1 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
| 0.0 | 2.8 | GO:0006906 | vesicle fusion(GO:0006906) |
| 0.0 | 0.3 | GO:0051974 | negative regulation of telomerase activity(GO:0051974) |
| 0.0 | 0.1 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.0 | 0.0 | GO:0061341 | non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
| 0.0 | 0.1 | GO:0051882 | mitochondrial depolarization(GO:0051882) |
| 0.0 | 1.2 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 1.4 | GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844) |
| 0.0 | 0.2 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.0 | 0.1 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.0 | 0.2 | GO:0071225 | cellular response to muramyl dipeptide(GO:0071225) |
| 0.0 | 0.1 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.0 | 0.0 | GO:0070488 | neutrophil aggregation(GO:0070488) |
| 0.0 | 0.3 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 0.2 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.4 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.0 | 0.9 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
| 0.0 | 0.4 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 6.0 | GO:0005595 | collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934) |
| 1.8 | 12.6 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418) |
| 1.8 | 5.3 | GO:0071953 | elastic fiber(GO:0071953) |
| 1.4 | 5.6 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 1.4 | 6.9 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 1.3 | 3.8 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.6 | 1.9 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.6 | 1.9 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.5 | 7.4 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.5 | 4.1 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.3 | 1.0 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 0.3 | 1.0 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.3 | 1.1 | GO:0043259 | laminin-10 complex(GO:0043259) |
| 0.2 | 2.5 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.2 | 3.7 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.2 | 1.9 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.2 | 2.6 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.2 | 2.2 | GO:0030128 | clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.2 | 12.9 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.2 | 2.9 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 1.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 0.5 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 4.0 | GO:0097546 | ciliary base(GO:0097546) |
| 0.1 | 0.9 | GO:0042825 | TAP complex(GO:0042825) |
| 0.1 | 1.0 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 0.3 | GO:1990879 | CST complex(GO:1990879) |
| 0.1 | 0.9 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 0.6 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.1 | 0.7 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 2.1 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 0.9 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.1 | 4.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 0.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 1.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 0.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.1 | 1.7 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 1.8 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.1 | 0.2 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.0 | 0.9 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 1.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 1.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.1 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 2.8 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 2.2 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.9 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 5.3 | GO:0043292 | contractile fiber(GO:0043292) |
| 0.0 | 2.6 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.0 | 3.2 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.3 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 1.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 1.3 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.2 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 0.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 1.4 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 2.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 7.8 | GO:0044297 | cell body(GO:0044297) |
| 0.0 | 0.7 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 5.3 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.5 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.2 | GO:0031988 | membrane-bounded vesicle(GO:0031988) |
| 0.0 | 7.1 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 0.4 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.6 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 0.1 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 0.6 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.1 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 1.3 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 0.0 | 0.8 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.5 | GO:0072562 | blood microparticle(GO:0072562) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.9 | 15.5 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 2.9 | 17.3 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 1.5 | 7.4 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 1.4 | 8.5 | GO:0015265 | urea channel activity(GO:0015265) |
| 1.0 | 3.8 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
| 0.9 | 5.4 | GO:0019841 | retinol binding(GO:0019841) |
| 0.9 | 2.6 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.9 | 4.3 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.7 | 9.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.5 | 12.6 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.5 | 8.2 | GO:0008430 | selenium binding(GO:0008430) |
| 0.5 | 2.0 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.5 | 2.0 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.5 | 1.4 | GO:0008521 | acetyl-CoA transporter activity(GO:0008521) |
| 0.4 | 1.8 | GO:0003884 | D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922) |
| 0.4 | 2.0 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.4 | 1.5 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
| 0.4 | 1.9 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.4 | 1.1 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) |
| 0.4 | 1.5 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.4 | 5.1 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.4 | 1.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.4 | 1.4 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.4 | 1.1 | GO:0035175 | histone kinase activity (H3-S10 specific)(GO:0035175) |
| 0.3 | 1.0 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 0.3 | 1.9 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.3 | 4.5 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.3 | 1.5 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.3 | 0.9 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.3 | 2.1 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.3 | 2.6 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.3 | 7.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.3 | 2.3 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.3 | 1.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.3 | 0.3 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.3 | 1.5 | GO:0009374 | biotin binding(GO:0009374) |
| 0.2 | 5.1 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.2 | 0.9 | GO:0023029 | peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980) |
| 0.2 | 0.6 | GO:0005534 | galactose binding(GO:0005534) |
| 0.2 | 1.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.2 | 4.4 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.2 | 0.5 | GO:0050827 | toxin receptor binding(GO:0050827) |
| 0.1 | 0.7 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.1 | 0.6 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 2.4 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.1 | 1.1 | GO:0004779 | sulfate adenylyltransferase activity(GO:0004779) |
| 0.1 | 1.7 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 12.8 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 0.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.3 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
| 0.1 | 4.2 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 3.5 | GO:0045309 | protein phosphorylated amino acid binding(GO:0045309) |
| 0.1 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 2.2 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 2.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 2.0 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 0.9 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.4 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
| 0.1 | 2.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 0.6 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
| 0.1 | 1.6 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 3.3 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 1.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 6.4 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 0.7 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.1 | 0.9 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.1 | 2.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 1.8 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 1.2 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.1 | 0.7 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 1.2 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 0.2 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.1 | 0.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 0.2 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.1 | 1.1 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) |
| 0.0 | 0.2 | GO:0036122 | BMP binding(GO:0036122) |
| 0.0 | 0.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 1.9 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
| 0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) angiostatin binding(GO:0043532) |
| 0.0 | 0.5 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.8 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
| 0.0 | 0.4 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.0 | 0.6 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.0 | 1.3 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
| 0.0 | 6.1 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 3.4 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.0 | 0.9 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.6 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.7 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
| 0.0 | 0.3 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.0 | 1.7 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
| 0.0 | 0.1 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.0 | 0.6 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.3 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.1 | GO:0004368 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) |
| 0.0 | 0.2 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
| 0.0 | 0.6 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 1.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 1.5 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 2.7 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 0.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.1 | GO:0070976 | TIR domain binding(GO:0070976) |
| 0.0 | 0.2 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.9 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.6 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 0.1 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 1.3 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.0 | 0.5 | GO:0004601 | peroxidase activity(GO:0004601) |
| 0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 1.5 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.1 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.5 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
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