Motif ID: Nfil3_Tef

Z-value: 2.101

Transcription factors associated with Nfil3_Tef:

Gene SymbolEntrez IDGene Name
Nfil3 ENSMUSG00000056749.7 Nfil3
Tef ENSMUSG00000022389.8 Tef

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tefmm10_v2_chr15_+_81811414_818114910.899.9e-10Click!
Nfil3mm10_v2_chr13_-_52981027_529810830.601.3e-03Click!


Activity profile for motif Nfil3_Tef.

activity profile for motif Nfil3_Tef


Sorted Z-values histogram for motif Nfil3_Tef

Sorted Z-values for motif Nfil3_Tef



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfil3_Tef

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 18.451 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr14_+_65971049 12.972 ENSMUST00000128539.1
 Clu
clusterin
chr14_+_65970804 12.320 ENSMUST00000138191.1
 Clu
clusterin
chr5_+_117841839 11.145 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr14_+_65971164 10.829 ENSMUST00000144619.1
 Clu
clusterin
chr14_+_65970610 10.512 ENSMUST00000127387.1
 Clu
clusterin
chr9_-_40346290 10.223 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr1_-_91459254 10.101 ENSMUST00000069620.8
 Per2
period circadian clock 2
chr6_-_113934679 8.577 ENSMUST00000101044.2
 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr16_+_45093611 8.251 ENSMUST00000099498.2
 Ccdc80
coiled-coil domain containing 80
chrX_-_51681703 7.801 ENSMUST00000088172.5
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr2_+_131909928 7.569 ENSMUST00000091288.6
 Prnp
prion protein
chr2_-_25469742 7.560 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr11_-_101785252 7.313 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr4_+_85205417 7.185 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
 Sh3gl2


SH3-domain GRB2-like 2


chr2_+_131909951 7.168 ENSMUST00000124100.1
ENSMUST00000136783.1
 PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chrX_-_51681856 7.074 ENSMUST00000114871.1
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr16_-_22439570 6.800 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr7_-_103827922 6.627 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr12_+_74288735 6.243 ENSMUST00000095617.1
 1700086L19Rik
RIKEN cDNA 1700086L19 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.8 46.6 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.9 18.5 GO:0021542 dentate gyrus development(GO:0021542)
2.5 14.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
2.0 14.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
2.7 13.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 11.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
2.8 11.1 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
1.7 10.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 8.8 GO:0007623 circadian rhythm(GO:0007623)
1.4 8.6 GO:0048840 otolith development(GO:0048840)
0.1 8.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
2.0 7.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
3.8 7.6 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
1.5 7.4 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 5.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.4 5.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
1.3 5.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.3 5.2 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.6 5.1 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 4.9 GO:0030279 negative regulation of ossification(GO:0030279)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.7 46.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 12.5 GO:0031225 anchored component of membrane(GO:0031225)
1.0 11.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.6 9.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 9.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 8.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.5 8.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 8.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.5 7.8 GO:0043205 fibril(GO:0043205)
1.7 6.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 6.6 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3 5.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 5.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 4.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 4.3 GO:0045202 synapse(GO:0045202)
1.4 4.1 GO:0043512 inhibin A complex(GO:0043512)
0.6 4.0 GO:0070695 FHF complex(GO:0070695)
0.4 4.0 GO:0005883 neurofilament(GO:0005883)
0.1 4.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 3.8 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 84 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 46.6 GO:0051787 misfolded protein binding(GO:0051787)
0.5 16.5 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
3.3 13.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 11.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
3.6 10.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 10.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.7 8.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.7 8.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 8.3 GO:0001968 fibronectin binding(GO:0001968)
0.4 6.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
1.7 6.6 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.0 5.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 5.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 5.5 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.3 5.3 GO:0004385 guanylate kinase activity(GO:0004385)
1.3 5.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.7 5.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.6 4.9 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 4.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 4.4 GO:0008565 protein transporter activity(GO:0008565)