Motif ID: Nfix

Z-value: 1.565


Transcription factors associated with Nfix:

Gene SymbolEntrez IDGene Name
Nfix ENSMUSG00000001911.10 Nfix

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfixmm10_v2_chr8_-_84773381_847734270.854.3e-08Click!


Activity profile for motif Nfix.

activity profile for motif Nfix


Sorted Z-values histogram for motif Nfix

Sorted Z-values for motif Nfix



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfix

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_141524379 18.229 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr7_-_97417730 10.440 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr7_-_103827922 8.906 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr1_-_56969827 8.314 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr15_-_81499548 7.832 ENSMUST00000172270.1
 Gm5218
predicted gene 5218
chr1_-_56969864 7.500 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr7_+_130936172 7.441 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr4_+_48045144 7.353 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr5_+_66745835 7.047 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
 Limch1



LIM and calponin homology domains 1



chr13_+_83504032 6.679 ENSMUST00000163888.1
ENSMUST00000005722.7
 Mef2c

myocyte enhancer factor 2C

chr6_-_126166726 6.603 ENSMUST00000112244.2
ENSMUST00000050484.7
 Ntf3

neurotrophin 3

chr18_-_78123324 6.588 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1

chr13_+_16014457 6.509 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr11_-_102897123 5.857 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr5_+_66968961 5.613 ENSMUST00000132991.1
 Limch1
LIM and calponin homology domains 1
chr17_-_46440099 5.572 ENSMUST00000166852.1
 Gm5093
predicted gene 5093
chr16_+_42907563 5.438 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chrX_-_141874870 5.243 ENSMUST00000182079.1
 Gm15294
predicted gene 15294
chr4_+_105790534 5.098 ENSMUST00000185012.1
 Gm12728
predicted gene 12728
chr18_-_23038656 4.894 ENSMUST00000081423.6
 Nol4
nucleolar protein 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 18.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.0 15.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 12.5 GO:0031032 actomyosin structure organization(GO:0031032)
0.4 10.2 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
1.6 9.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.5 8.4 GO:0060134 prepulse inhibition(GO:0060134)
0.1 7.8 GO:0002181 cytoplasmic translation(GO:0002181)
2.5 7.4 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.2 7.4 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 7.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 7.2 GO:0032060 bleb assembly(GO:0032060)
2.2 6.7 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
1.3 6.6 GO:0007403 glial cell fate determination(GO:0007403)
1.1 6.6 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
1.3 6.5 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.5 6.4 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
1.0 6.2 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 5.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 5.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 5.1 GO:0060612 adipose tissue development(GO:0060612)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 24.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 17.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 13.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 13.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 9.8 GO:0005911 cell-cell junction(GO:0005911)
2.4 9.6 GO:0097450 astrocyte end-foot(GO:0097450)
2.2 8.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
2.2 6.5 GO:0043512 inhibin A complex(GO:0043512)
0.0 6.3 GO:0016607 nuclear speck(GO:0016607)
0.3 5.8 GO:0000930 gamma-tubulin complex(GO:0000930)
1.0 4.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.6 4.7 GO:0014802 terminal cisterna(GO:0014802)
0.9 4.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 4.7 GO:0036477 somatodendritic compartment(GO:0036477)
0.2 4.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 4.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 3.9 GO:0043218 compact myelin(GO:0043218)
0.1 3.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 3.4 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.6 18.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 14.1 GO:0003735 structural constituent of ribosome(GO:0003735)
2.2 8.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 8.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 7.6 GO:0005504 fatty acid binding(GO:0005504)
0.5 7.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 7.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.6 6.7 GO:0003680 AT DNA binding(GO:0003680)
1.3 6.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.1 6.6 GO:0015265 urea channel activity(GO:0015265)
0.0 6.6 GO:0003779 actin binding(GO:0003779)
1.1 6.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 6.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 5.8 GO:0043015 gamma-tubulin binding(GO:0043015)
1.6 4.9 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.8 4.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.8 4.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.4 4.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 4.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 3.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)