Motif ID: Nfkb2

Z-value: 0.297


Transcription factors associated with Nfkb2:

Gene SymbolEntrez IDGene Name
Nfkb2 ENSMUSG00000025225.8 Nfkb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfkb2mm10_v2_chr19_+_46304709_46304811-0.442.3e-02Click!


Activity profile for motif Nfkb2.

activity profile for motif Nfkb2


Sorted Z-values histogram for motif Nfkb2

Sorted Z-values for motif Nfkb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfkb2

PNG image of the network

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Top targets:


Showing 1 to 20 of 73 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_33147400 0.489 ENSMUST00000020507.7
 Fgf18
fibroblast growth factor 18
chr5_+_90759299 0.328 ENSMUST00000031318.4
 Cxcl5
chemokine (C-X-C motif) ligand 5
chr15_-_102246439 0.304 ENSMUST00000063339.7
 Rarg
retinoic acid receptor, gamma
chr7_+_19176416 0.284 ENSMUST00000117338.1
 Eml2
echinoderm microtubule associated protein like 2
chr7_+_29289300 0.278 ENSMUST00000048187.4
 Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr14_+_80000292 0.266 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chrX_+_163908982 0.253 ENSMUST00000069041.8
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr5_+_110544326 0.225 ENSMUST00000040001.7
 Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr19_+_7268296 0.223 ENSMUST00000066646.4
 Rcor2
REST corepressor 2
chr19_+_6341121 0.220 ENSMUST00000025897.6
ENSMUST00000130382.1
 Map4k2

mitogen-activated protein kinase kinase kinase kinase 2

chr17_+_35424842 0.208 ENSMUST00000174699.1
 H2-Q6
histocompatibility 2, Q region locus 6
chr1_+_167001417 0.207 ENSMUST00000165874.1
 Fam78b
family with sequence similarity 78, member B
chr14_-_30626196 0.197 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
 Prkcd


protein kinase C, delta


chr11_+_70029742 0.182 ENSMUST00000132597.2
 Dlg4
discs, large homolog 4 (Drosophila)
chr17_+_35379608 0.181 ENSMUST00000081435.4
 H2-Q4
histocompatibility 2, Q region locus 4
chrX_+_163909132 0.167 ENSMUST00000033734.7
ENSMUST00000112294.2
 Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr14_-_30607808 0.159 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
 Prkcd



protein kinase C, delta



chr1_+_135132693 0.159 ENSMUST00000049449.4
 Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr2_-_37422869 0.158 ENSMUST00000112936.1
ENSMUST00000112934.1
 Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr11_-_84870712 0.153 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
 Ggnbp2



gametogenetin binding protein 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.5 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.4 GO:0006680 glucosylceramide catabolic process(GO:0006680) negative regulation of filopodium assembly(GO:0051490)
0.0 0.4 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 0.3 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.1 0.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.2 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.0 0.2 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.2 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0045472 response to ether(GO:0045472) negative regulation of interleukin-1 beta secretion(GO:0050713) negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.0 GO:0097512 cardiac myofibril(GO:0097512)

Gene overrepresentation in molecular_function category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)