Motif ID: Nkx2-2
Z-value: 1.174

Transcription factors associated with Nkx2-2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nkx2-2 | ENSMUSG00000027434.10 | Nkx2-2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nkx2-2 | mm10_v2_chr2_-_147186389_147186413 | 0.09 | 6.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 80 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.9 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.3 | 5.5 | GO:0070986 | left/right axis specification(GO:0070986) |
1.5 | 4.6 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
0.3 | 2.7 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
0.1 | 2.4 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
0.6 | 2.3 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.2 | 2.3 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
0.1 | 2.2 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
0.4 | 1.9 | GO:0060242 | contact inhibition(GO:0060242) |
0.2 | 1.8 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.2 | 1.8 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 1.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.6 | 1.7 | GO:0007525 | somatic muscle development(GO:0007525) |
0.1 | 1.7 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
0.4 | 1.6 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
0.1 | 1.5 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
0.5 | 1.4 | GO:0046078 | deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) dUMP metabolic process(GO:0046078) |
0.4 | 1.3 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
0.3 | 1.3 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
0.2 | 1.3 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 35 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 10.9 | GO:0005730 | nucleolus(GO:0005730) |
0.1 | 5.5 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 4.1 | GO:0005667 | transcription factor complex(GO:0005667) |
0.1 | 3.4 | GO:0034451 | centriolar satellite(GO:0034451) |
0.6 | 2.5 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
0.6 | 2.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.0 | 1.9 | GO:0005902 | microvillus(GO:0005902) |
0.6 | 1.7 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
0.1 | 1.7 | GO:0070938 | contractile ring(GO:0070938) |
0.1 | 1.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.2 | 1.3 | GO:0001940 | male pronucleus(GO:0001940) |
0.3 | 1.2 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.0 | 1.2 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 1.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.2 | 1.1 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.1 | 1.1 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 1.1 | GO:0016605 | PML body(GO:0016605) |
0.3 | 1.0 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
0.1 | 1.0 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.2 | 0.9 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 58 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.9 | GO:0000049 | tRNA binding(GO:0000049) |
0.2 | 4.6 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 3.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.3 | 2.3 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.1 | 1.9 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 1.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 1.8 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 1.8 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.2 | 1.7 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.1 | 1.7 | GO:0017166 | vinculin binding(GO:0017166) |
0.0 | 1.5 | GO:0051015 | actin filament binding(GO:0051015) |
0.1 | 1.4 | GO:0005542 | folic acid binding(GO:0005542) |
0.1 | 1.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.4 | 1.2 | GO:0004008 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
0.2 | 1.2 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.0 | 1.2 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.4 | 1.1 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
0.0 | 1.1 | GO:0045502 | dynein binding(GO:0045502) |
0.3 | 1.0 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.2 | 1.0 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |