Motif ID: Nkx2-3

Z-value: 0.747


Transcription factors associated with Nkx2-3:

Gene SymbolEntrez IDGene Name
Nkx2-3 ENSMUSG00000044220.12 Nkx2-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-3mm10_v2_chr19_+_43612299_43612325-0.086.9e-01Click!


Activity profile for motif Nkx2-3.

activity profile for motif Nkx2-3


Sorted Z-values histogram for motif Nkx2-3

Sorted Z-values for motif Nkx2-3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_38783503 5.052 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr12_+_38783455 4.140 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr15_+_92597104 2.015 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr2_+_73271925 1.648 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr12_+_38780284 1.596 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr2_-_114013619 1.567 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr11_-_98053415 1.496 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr1_-_45890078 1.490 ENSMUST00000183590.1
Gm5269
predicted gene 5269
chr7_-_19699008 1.454 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr12_+_38780817 1.436 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr5_-_62766153 1.424 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_136171722 1.416 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr16_+_7069825 1.415 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_-_139714481 1.395 ENSMUST00000183728.1
Gm15013
predicted gene 15013
chr3_+_55461758 1.393 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr15_+_99006056 1.324 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr13_+_83504032 1.295 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr1_+_19103022 1.214 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr1_-_78968079 1.152 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr6_-_6882068 1.074 ENSMUST00000142635.1
ENSMUST00000052609.8
Dlx5

distal-less homeobox 5

chr11_+_16257706 1.070 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr8_-_109251698 1.047 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr4_-_45532470 0.998 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr18_-_31447383 0.982 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr15_+_92051153 0.978 ENSMUST00000169825.1
Cntn1
contactin 1
chr12_+_58211772 0.968 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr2_+_22622183 0.882 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr5_+_117781017 0.875 ENSMUST00000138579.2
Nos1
nitric oxide synthase 1, neuronal
chr10_+_106470281 0.841 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chrX_-_143933204 0.781 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chrX_-_143933089 0.763 ENSMUST00000087313.3
Dcx
doublecortin
chr12_+_38781093 0.748 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr8_-_105637403 0.741 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr12_+_74297474 0.729 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr12_-_83487708 0.714 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr15_+_21111452 0.708 ENSMUST00000075132.6
Cdh12
cadherin 12
chr5_-_62765618 0.706 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_57524734 0.699 ENSMUST00000089494.4
Il17d
interleukin 17D
chr1_+_72284367 0.693 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr2_-_65529275 0.693 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_+_19907774 0.687 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_40346290 0.681 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr16_-_74411292 0.675 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr9_-_79718631 0.643 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr15_-_43869993 0.642 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr5_-_73191848 0.639 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr10_-_95673451 0.634 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr17_+_3397189 0.627 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr5_+_37050854 0.621 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr16_-_3909192 0.613 ENSMUST00000181699.1
1700016D08Rik
RIKEN cDNA 1700016D08 gene
chr19_-_59170978 0.613 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr1_-_162859684 0.610 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr16_-_19706365 0.593 ENSMUST00000081880.5
Lamp3
lysosomal-associated membrane protein 3
chr11_-_79504078 0.585 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr15_+_18818895 0.585 ENSMUST00000166873.2
Cdh10
cadherin 10
chr3_+_62419668 0.584 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr9_-_79718720 0.582 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr12_-_72408934 0.581 ENSMUST00000078505.7
Rtn1
reticulon 1
chr4_+_127172866 0.565 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr4_+_119814495 0.559 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr12_+_52699297 0.554 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr13_+_42866247 0.527 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr7_+_144838590 0.525 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr19_-_44552831 0.524 ENSMUST00000166808.1
Gm20538
predicted gene 20538
chr6_+_145934113 0.523 ENSMUST00000032383.7
Sspn
sarcospan
chrX_-_16911774 0.518 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr3_-_26133734 0.517 ENSMUST00000108308.3
ENSMUST00000075054.4
Nlgn1

neuroligin 1

chr4_+_102589687 0.500 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr2_-_147186389 0.489 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr3_+_68869563 0.485 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr8_+_54954728 0.478 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr6_+_112273758 0.466 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr5_+_19907502 0.463 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_-_90088343 0.456 ENSMUST00000173917.1
Nrxn1
neurexin I
chr9_-_79718518 0.455 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr10_+_29211637 0.454 ENSMUST00000092627.4
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr3_-_154328634 0.443 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr2_-_36104060 0.441 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr1_+_66321708 0.435 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr16_-_74411776 0.434 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr3_-_110143937 0.426 ENSMUST00000051253.3
Ntng1
netrin G1
chr18_+_37755718 0.426 ENSMUST00000061279.7
Pcdhga9
protocadherin gamma subfamily A, 9
chr3_-_85741389 0.421 ENSMUST00000094148.4
Fam160a1
family with sequence similarity 160, member A1
chr6_+_134981998 0.420 ENSMUST00000167323.1
Apold1
apolipoprotein L domain containing 1
chr1_-_14310198 0.419 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr18_+_37300799 0.411 ENSMUST00000051754.1
Pcdhb3
protocadherin beta 3
chr13_+_51408618 0.409 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr16_+_43235856 0.401 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chrX_+_142227923 0.399 ENSMUST00000042329.5
Nxt2
nuclear transport factor 2-like export factor 2
chr13_+_42680565 0.393 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chrX_+_93654863 0.391 ENSMUST00000113933.2
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr1_+_191025350 0.383 ENSMUST00000181050.1
A230020J21Rik
RIKEN cDNA A230020J21 gene
chr12_-_16589743 0.380 ENSMUST00000111067.2
ENSMUST00000067124.5
Lpin1

lipin 1

chr8_-_31918203 0.379 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr19_+_26753588 0.378 ENSMUST00000177116.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_-_37459327 0.369 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr4_+_48049080 0.368 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr8_+_85432686 0.361 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr5_+_89027959 0.360 ENSMUST00000130041.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr5_-_137601043 0.360 ENSMUST00000037620.7
ENSMUST00000154708.1
Mospd3

motile sperm domain containing 3

chr18_+_69593361 0.354 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr10_+_24149291 0.353 ENSMUST00000020174.5
Stx7
syntaxin 7
chr2_-_45117349 0.347 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr6_+_63255971 0.333 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chrX_+_150547375 0.332 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr10_+_94576254 0.329 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr1_+_66322102 0.323 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr1_-_190170671 0.319 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chrX_+_99975570 0.319 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr11_-_87359011 0.316 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr5_+_89028035 0.307 ENSMUST00000113216.2
ENSMUST00000134303.1
Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr19_-_4121536 0.304 ENSMUST00000025767.7
Aip
aryl-hydrocarbon receptor-interacting protein
chr4_+_97777780 0.304 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr3_-_154330543 0.298 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr9_+_32116040 0.297 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr11_+_114727384 0.293 ENSMUST00000069325.7
Dnaic2
dynein, axonemal, intermediate chain 2
chr6_-_57535422 0.285 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr10_+_94575257 0.283 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr15_+_55307743 0.283 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr17_-_29888570 0.282 ENSMUST00000171691.1
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr12_-_11436607 0.280 ENSMUST00000072299.5
Vsnl1
visinin-like 1
chr1_+_132298606 0.275 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr5_-_84417359 0.271 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr11_+_94044194 0.266 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr10_+_69925954 0.262 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr6_+_15196949 0.260 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr4_-_110290884 0.260 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_-_20968526 0.256 ENSMUST00000141298.2
ENSMUST00000125783.2
Arhgap21

Rho GTPase activating protein 21

chr14_-_62454793 0.254 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr2_-_175133322 0.252 ENSMUST00000099029.3
Gm14399
predicted gene 14399
chr2_-_64975762 0.251 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr3_-_86548268 0.250 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr7_-_27553138 0.247 ENSMUST00000127240.1
ENSMUST00000117095.1
ENSMUST00000117611.1
Pld3


phospholipase D family, member 3


chr1_+_110099295 0.246 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr11_+_94044111 0.241 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr11_-_116189542 0.239 ENSMUST00000148601.1
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr17_+_25188380 0.237 ENSMUST00000039734.5
Unkl
unkempt-like (Drosophila)
chr2_-_7395879 0.235 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr18_+_37518341 0.233 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr4_-_110286581 0.233 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_-_63184253 0.233 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr1_-_190170178 0.231 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr11_+_94044331 0.229 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr16_+_10812915 0.226 ENSMUST00000115822.1
Gm11172
predicted gene 11172
chr10_-_56228636 0.223 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr2_-_45112890 0.222 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr8_+_13060908 0.218 ENSMUST00000033822.2
Proz
protein Z, vitamin K-dependent plasma glycoprotein
chr1_+_179961110 0.210 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr12_+_71048338 0.210 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr11_+_94044241 0.202 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr4_-_91376433 0.202 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr5_+_57718021 0.202 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr2_-_79456750 0.199 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr4_+_59035088 0.199 ENSMUST00000041160.6
Gng10
guanine nucleotide binding protein (G protein), gamma 10
chr3_+_122419772 0.192 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr2_+_23069210 0.187 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr1_-_140183404 0.186 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr13_-_113663670 0.186 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr2_-_63184170 0.186 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr11_-_26210553 0.185 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr16_+_20693263 0.185 ENSMUST00000149543.1
ENSMUST00000118919.1
Fam131a

family with sequence similarity 131, member A

chr4_-_91376490 0.184 ENSMUST00000107124.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_+_10088173 0.181 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chr1_+_180111339 0.181 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr4_-_110292719 0.179 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr16_-_35769356 0.177 ENSMUST00000023554.8
Dirc2
disrupted in renal carcinoma 2 (human)
chr1_+_187997821 0.176 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr11_+_103133303 0.174 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chrX_+_112615301 0.170 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr9_+_113812547 0.169 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr1_+_187997835 0.169 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr3_+_138065052 0.166 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr5_-_72587544 0.166 ENSMUST00000031124.4
Gm5868
predicted gene 5868
chr2_-_84425258 0.164 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr13_-_36734450 0.164 ENSMUST00000037623.8
Nrn1
neuritin 1
chr13_-_28953690 0.162 ENSMUST00000067230.5
Sox4
SRY-box containing gene 4
chr11_+_103133333 0.159 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr2_+_116067933 0.159 ENSMUST00000156095.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr12_-_56536895 0.157 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr19_-_53371766 0.153 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr19_+_5474681 0.151 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr15_+_66577536 0.150 ENSMUST00000048188.8
Phf20l1
PHD finger protein 20-like 1
chr3_-_126998408 0.147 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chrX_-_59568068 0.145 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr12_-_98259416 0.139 ENSMUST00000021390.7
Galc
galactosylceramidase
chr9_+_34486125 0.135 ENSMUST00000115148.2
ENSMUST00000183580.1
Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr4_-_41723129 0.133 ENSMUST00000171641.1
ENSMUST00000030158.4
Dctn3

dynactin 3

chr8_+_83666827 0.127 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr10_-_20725023 0.127 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr1_+_179960472 0.124 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr5_-_5266038 0.123 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr5_-_99252839 0.121 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr5_+_144100387 0.117 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chrX_-_23285532 0.117 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr11_-_37235882 0.113 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr2_+_61593125 0.110 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chr15_-_73061204 0.108 ENSMUST00000089770.3
ENSMUST00000170633.1
ENSMUST00000168191.1
Trappc9


trafficking protein particle complex 9


chr1_-_93101825 0.105 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr4_-_45408646 0.104 ENSMUST00000153904.1
ENSMUST00000132815.2
ENSMUST00000107796.1
ENSMUST00000116341.3
Slc25a51



solute carrier family 25, member 51



chr12_-_56535047 0.104 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.4 1.3 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.4 12.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.4 1.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 1.1 GO:0060166 olfactory pit development(GO:0060166)
0.3 1.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.9 GO:0006538 glutamate catabolic process(GO:0006538)
0.2 0.9 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.2 0.5 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 0.5 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
0.1 1.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 1.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.6 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.7 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 1.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.9 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.6 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 1.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.1 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.6 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.2 GO:0003289 atrial septum primum morphogenesis(GO:0003289) noradrenergic neuron differentiation(GO:0003357) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.3 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.4 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 1.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.6 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0045472 response to ether(GO:0045472)
0.0 0.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.6 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0015867 ATP transport(GO:0015867)
0.0 1.6 GO:0007601 visual perception(GO:0007601)
0.0 1.0 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.3 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 0.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)
0.0 0.3 GO:0060074 synapse maturation(GO:0060074)
0.0 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.0 0.1 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 0.4 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.3 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.5 1.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 1.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.6 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 2.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.1 GO:0071565 nBAF complex(GO:0071565)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640) sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 1.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 0.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.6 GO:0043495 protein anchor(GO:0043495)
0.1 0.5 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 11.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.1 GO:0015217 ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.0 0.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)