Motif ID: Nkx3-1

Z-value: 0.918


Transcription factors associated with Nkx3-1:

Gene SymbolEntrez IDGene Name
Nkx3-1 ENSMUSG00000022061.8 Nkx3-1



Activity profile for motif Nkx3-1.

activity profile for motif Nkx3-1


Sorted Z-values histogram for motif Nkx3-1

Sorted Z-values for motif Nkx3-1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx3-1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_13324160 5.399 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr4_-_140774196 5.031 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chrX_+_100625737 4.279 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr9_+_78191966 3.453 ENSMUST00000034903.5
Gsta4
glutathione S-transferase, alpha 4
chr4_-_132757162 3.442 ENSMUST00000030709.8
Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
chr1_-_163289214 3.240 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr9_+_72438534 3.168 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr9_+_72438519 3.055 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chrX_+_56454871 3.045 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chrX_+_164269371 2.805 ENSMUST00000145412.1
ENSMUST00000033749.7
Pir

pirin

chr10_-_13324250 2.667 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr6_+_128362919 2.512 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr10_-_12861735 2.512 ENSMUST00000076817.4
Utrn
utrophin
chr1_-_175688353 2.490 ENSMUST00000104984.1
Chml
choroideremia-like
chr8_+_114133557 2.348 ENSMUST00000073521.5
ENSMUST00000066514.6
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr8_+_114133635 2.277 ENSMUST00000147605.1
ENSMUST00000134593.1
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr3_-_104818539 2.274 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr18_+_60963517 2.241 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chrX_-_75875101 2.233 ENSMUST00000114059.3
Pls3
plastin 3 (T-isoform)
chr17_+_56304313 2.200 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr12_+_52516077 2.190 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr5_-_8422582 2.157 ENSMUST00000168500.1
ENSMUST00000002368.9
Dbf4

DBF4 homolog (S. cerevisiae)

chr8_-_123318553 2.097 ENSMUST00000118395.1
ENSMUST00000035495.8
Fanca

Fanconi anemia, complementation group A

chr3_-_57575907 2.087 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chrX_-_75874536 2.050 ENSMUST00000033547.7
Pls3
plastin 3 (T-isoform)
chr3_-_57575760 2.027 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr9_-_20976762 1.998 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr5_-_86676346 1.883 ENSMUST00000038448.6
Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr4_+_32623985 1.792 ENSMUST00000108178.1
Casp8ap2
caspase 8 associated protein 2
chr18_+_82910863 1.711 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr15_-_50882806 1.661 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr1_-_53297001 1.607 ENSMUST00000126590.1
ENSMUST00000126412.1
ENSMUST00000135246.1
ENSMUST00000027267.7
Pms1



postmeiotic segregation increased 1 (S. cerevisiae)



chr17_-_25727364 1.592 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr10_+_94514825 1.569 ENSMUST00000065060.5
Tmcc3
transmembrane and coiled coil domains 3
chr10_+_100488289 1.558 ENSMUST00000164751.1
Cep290
centrosomal protein 290
chr2_+_71873224 1.509 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr7_+_58658181 1.475 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr7_+_75455534 1.390 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr5_-_149051300 1.385 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr2_+_110597298 1.292 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr1_-_133907053 1.236 ENSMUST00000149380.1
ENSMUST00000124051.2
Optc

opticin

chr4_+_3940747 1.189 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr4_+_116708571 1.184 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
Ccdc163



coiled-coil domain containing 163



chr1_-_133906973 1.169 ENSMUST00000126123.1
Optc
opticin
chrX_-_111537947 1.126 ENSMUST00000132319.1
ENSMUST00000123951.1
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr12_+_76324905 1.118 ENSMUST00000172992.1
Akap5
A kinase (PRKA) anchor protein 5
chr13_-_99900645 1.106 ENSMUST00000022150.6
Cartpt
CART prepropeptide
chr19_-_61297069 1.094 ENSMUST00000179346.1
Gm21060
predicted gene, 21060
chr7_+_123123870 1.093 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr10_+_4432467 1.080 ENSMUST00000095893.4
ENSMUST00000118544.1
ENSMUST00000117489.1
1700052N19Rik


RIKEN cDNA 1700052N19 gene


chr17_+_37270214 1.073 ENSMUST00000038580.6
H2-M3
histocompatibility 2, M region locus 3
chr7_+_43607169 1.071 ENSMUST00000120935.1
ENSMUST00000127765.1
ENSMUST00000032661.7
Zfp819


zinc finger protein 819


chrX_+_56317608 1.066 ENSMUST00000151426.1
ENSMUST00000138262.1
1600025M17Rik

RIKEN cDNA 1600025M17 gene

chr18_-_6241470 1.059 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr12_+_76324860 1.050 ENSMUST00000095610.2
ENSMUST00000154078.2
Akap5

A kinase (PRKA) anchor protein 5

chr5_-_21785115 0.967 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr5_-_72559599 0.965 ENSMUST00000074948.4
ENSMUST00000087216.5
Nfxl1

nuclear transcription factor, X-box binding-like 1

chr2_+_79707780 0.961 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
Ppp1r1c


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr17_-_56982120 0.943 ENSMUST00000056113.4
Acer1
alkaline ceramidase 1
chr9_-_124493793 0.942 ENSMUST00000178787.1
Gm21836
predicted gene, 21836
chr10_-_62486575 0.936 ENSMUST00000092473.3
Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr5_+_90367204 0.935 ENSMUST00000068250.3
Gm9958
predicted gene 9958
chr11_-_80080928 0.856 ENSMUST00000103233.3
ENSMUST00000061283.8
Crlf3

cytokine receptor-like factor 3

chr4_-_156255327 0.850 ENSMUST00000179919.1
Samd11
sterile alpha motif domain containing 11
chr11_-_21370452 0.849 ENSMUST00000102875.4
Ugp2
UDP-glucose pyrophosphorylase 2
chr18_-_6241486 0.846 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr14_+_47663756 0.833 ENSMUST00000022391.7
Ktn1
kinectin 1
chr10_-_62814539 0.832 ENSMUST00000173087.1
ENSMUST00000174121.1
Tet1

tet methylcytosine dioxygenase 1

chr9_+_77921908 0.813 ENSMUST00000133757.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr11_+_97685903 0.812 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chr1_-_156034800 0.806 ENSMUST00000169241.1
Tor1aip1
torsin A interacting protein 1
chr14_+_79515618 0.777 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr7_+_110627650 0.761 ENSMUST00000033054.8
Adm
adrenomedullin
chr2_-_84775388 0.722 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84775420 0.714 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr11_-_45955183 0.714 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr2_+_23069210 0.708 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr7_-_127930066 0.708 ENSMUST00000032988.8
Prss8
protease, serine, 8 (prostasin)
chr5_+_8422831 0.687 ENSMUST00000066921.3
Slc25a40
solute carrier family 25, member 40
chr9_+_78051938 0.660 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr10_-_14718191 0.639 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr11_+_97685794 0.612 ENSMUST00000107584.1
ENSMUST00000107585.2
Cisd3

CDGSH iron sulfur domain 3

chr1_-_193035651 0.606 ENSMUST00000016344.7
Syt14
synaptotagmin XIV
chr13_+_51408618 0.594 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr13_+_80886095 0.583 ENSMUST00000161441.1
Arrdc3
arrestin domain containing 3
chr13_-_74482943 0.569 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr13_-_41847482 0.565 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr14_-_54864055 0.530 ENSMUST00000142283.2
Homez
homeodomain leucine zipper-encoding gene
chr9_-_122310921 0.527 ENSMUST00000180685.1
Gm26797
predicted gene, 26797
chr9_-_35570393 0.514 ENSMUST00000115110.4
Hyls1
hydrolethalus syndrome 1
chr1_-_75046639 0.499 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chr9_-_43116514 0.487 ENSMUST00000061833.4
Tmem136
transmembrane protein 136
chr5_+_28071356 0.486 ENSMUST00000059155.10
Insig1
insulin induced gene 1
chr19_+_20601958 0.465 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr14_-_46831984 0.460 ENSMUST00000181311.1
ENSMUST00000074862.2
Gm10101

predicted gene 10101

chr3_+_14863495 0.456 ENSMUST00000029076.4
Car3
carbonic anhydrase 3
chr17_-_21933022 0.446 ENSMUST00000074295.7
Zfp942
zinc finger protein 942
chr1_+_135133272 0.444 ENSMUST00000167080.1
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chrX_-_100625901 0.435 ENSMUST00000059099.6
Pdzd11
PDZ domain containing 11
chr16_+_20611585 0.422 ENSMUST00000115522.2
ENSMUST00000119224.1
ENSMUST00000079600.4
ENSMUST00000120394.1
Ece2



endothelin converting enzyme 2



chr17_-_15564322 0.414 ENSMUST00000147532.1
Prdm9
PR domain containing 9
chr18_-_42262053 0.396 ENSMUST00000097590.3
Lars
leucyl-tRNA synthetase
chr8_-_23237623 0.388 ENSMUST00000033950.5
Gins4
GINS complex subunit 4 (Sld5 homolog)
chr14_-_104522615 0.375 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr9_-_89092835 0.374 ENSMUST00000167113.1
Trim43b
tripartite motif-containing 43B
chr9_+_89199319 0.366 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr14_-_52213379 0.365 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr17_-_65772686 0.362 ENSMUST00000070673.7
Rab31
RAB31, member RAS oncogene family
chr5_-_69592274 0.356 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
Gnpda2


glucosamine-6-phosphate deaminase 2


chr10_-_128211788 0.351 ENSMUST00000061995.8
Spryd4
SPRY domain containing 4
chr2_+_3114220 0.336 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr4_+_33310306 0.331 ENSMUST00000108153.2
ENSMUST00000029942.7
Rngtt

RNA guanylyltransferase and 5'-phosphatase

chrY_+_17874741 0.328 ENSMUST00000177639.1
Gm20831
predicted gene, 20831
chr8_-_95807458 0.320 ENSMUST00000098473.4
ENSMUST00000068452.8
Cnot1

CCR4-NOT transcription complex, subunit 1

chr11_-_17008647 0.298 ENSMUST00000102881.3
Plek
pleckstrin
chr18_-_12862624 0.293 ENSMUST00000121808.1
ENSMUST00000118313.1
Osbpl1a

oxysterol binding protein-like 1A

chr9_+_105053239 0.290 ENSMUST00000035177.8
ENSMUST00000149243.1
Mrpl3

mitochondrial ribosomal protein L3

chr17_-_35162969 0.281 ENSMUST00000174805.1
Prrc2a
proline-rich coiled-coil 2A
chr2_+_62664279 0.281 ENSMUST00000028257.2
Gca
grancalcin
chr5_+_107597760 0.277 ENSMUST00000112655.1
Rpap2
RNA polymerase II associated protein 2
chr2_-_84715160 0.253 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chrX_+_140456613 0.233 ENSMUST00000033809.3
Prps1
phosphoribosyl pyrophosphate synthetase 1
chr5_+_72914264 0.223 ENSMUST00000144843.1
Slain2
SLAIN motif family, member 2
chr9_+_40873981 0.217 ENSMUST00000067375.3
Bsx
brain specific homeobox
chr7_-_63938862 0.200 ENSMUST00000063694.8
Klf13
Kruppel-like factor 13
chr7_+_100537052 0.193 ENSMUST00000054310.3
Coa4
cytochrome c oxidase assembly factor 4
chr2_-_155582656 0.173 ENSMUST00000126322.1
Gss
glutathione synthetase
chr6_-_108185552 0.160 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr5_+_136919137 0.145 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr19_-_59943000 0.136 ENSMUST00000170819.1
Rab11fip2
RAB11 family interacting protein 2 (class I)
chrX_-_101222426 0.135 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr12_+_17266545 0.133 ENSMUST00000057288.5
Pdia6
protein disulfide isomerase associated 6
chr6_+_88465409 0.126 ENSMUST00000032165.9
Ruvbl1
RuvB-like protein 1
chr7_-_35318408 0.117 ENSMUST00000079693.5
Gpatch1
G patch domain containing 1
chr12_-_87233556 0.103 ENSMUST00000021423.7
Noxred1
NADP+ dependent oxidoreductase domain containing 1
chr1_-_174921813 0.103 ENSMUST00000055294.3
Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr2_+_163994960 0.095 ENSMUST00000018470.3
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr5_-_110046486 0.081 ENSMUST00000167969.1
Gm17655
predicted gene, 17655
chr6_-_69284319 0.068 ENSMUST00000103349.1
Igkv4-69
immunoglobulin kappa variable 4-69
chrX_+_7579666 0.043 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr7_+_100537192 0.041 ENSMUST00000120454.1
Coa4
cytochrome c oxidase assembly factor 4
chr17_-_25942821 0.022 ENSMUST00000148382.1
ENSMUST00000145745.1
Pigq

phosphatidylinositol glycan anchor biosynthesis, class Q

chr1_+_161142706 0.021 ENSMUST00000111608.1
ENSMUST00000052245.8
Ankrd45

ankyrin repeat domain 45

chr4_+_62619515 0.005 ENSMUST00000084521.4
ENSMUST00000107424.1
Rgs3

regulator of G-protein signaling 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.8 2.5 GO:0007525 somatic muscle development(GO:0007525)
0.7 2.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.6 4.3 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.6 4.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.6 5.0 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.5 3.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.5 1.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.5 1.9 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.5 1.4 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.4 2.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.4 6.2 GO:0070986 left/right axis specification(GO:0070986)
0.4 1.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.4 1.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.4 2.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739) amylase secretion(GO:0036394)
0.4 1.8 GO:0036337 Fas signaling pathway(GO:0036337)
0.4 1.1 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.3 2.5 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.3 2.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 2.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 0.8 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.2 3.2 GO:0048664 neuron fate determination(GO:0048664)
0.2 1.4 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 3.0 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 1.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.6 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 2.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.4 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.7 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 2.8 GO:0030224 monocyte differentiation(GO:0030224)
0.1 1.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 2.3 GO:0006379 mRNA cleavage(GO:0006379)
0.1 1.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.9 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) ceramide catabolic process(GO:0046514) sphingoid biosynthetic process(GO:0046520)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.8 GO:0097084 vascular smooth muscle cell development(GO:0097084) positive regulation of vasculogenesis(GO:2001214)
0.1 0.3 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 0.6 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.1 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.9 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.6 GO:0006298 mismatch repair(GO:0006298)
0.1 1.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.4 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 0.7 GO:0070633 transepithelial transport(GO:0070633)
0.1 1.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 2.2 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:2000642 negative regulation of vacuolar transport(GO:1903336) negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 1.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.9 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.3 GO:0033147 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.3 GO:0009301 snRNA transcription(GO:0009301)
0.0 1.0 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 1.0 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 2.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 3.0 GO:0060348 bone development(GO:0060348)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.4 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.5 2.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.4 1.6 GO:0005712 chiasma(GO:0005712)
0.3 0.8 GO:0097447 dendritic tree(GO:0097447)
0.2 4.7 GO:0031527 filopodium membrane(GO:0031527)
0.2 1.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 2.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.9 GO:0097422 tubular endosome(GO:0097422)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 1.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 4.3 GO:0032420 stereocilium(GO:0032420)
0.1 1.6 GO:0036038 MKS complex(GO:0036038)
0.1 6.2 GO:0005882 intermediate filament(GO:0005882)
0.1 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 4.3 GO:0005871 kinesin complex(GO:0005871)
0.1 2.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.1 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 2.2 GO:0000791 euchromatin(GO:0000791)
0.0 2.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 4.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 1.4 GO:0072562 blood microparticle(GO:0072562)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 5.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.8 5.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.7 2.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 1.4 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.4 3.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 6.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 1.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 2.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 0.9 GO:0071633 dihydroceramidase activity(GO:0071633)
0.3 1.8 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 2.8 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 2.5 GO:0017166 vinculin binding(GO:0017166)
0.1 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 2.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 3.6 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 2.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 3.2 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.8 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 1.4 GO:0001848 complement binding(GO:0001848)
0.1 1.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0016151 nickel cation binding(GO:0016151)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 1.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 4.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)