Motif ID: Nkx6-1_Evx1_Hesx1

Z-value: 0.706

Transcription factors associated with Nkx6-1_Evx1_Hesx1:

Gene SymbolEntrez IDGene Name
Evx1 ENSMUSG00000005503.8 Evx1
Hesx1 ENSMUSG00000040726.8 Hesx1
Nkx6-1 ENSMUSG00000035187.8 Nkx6-1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx6-1mm10_v2_chr5_-_101665195_101665226-0.582.0e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-1_Evx1_Hesx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_118052235 4.884 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr5_-_62766153 3.587 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_84417359 3.348 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr15_+_18818895 3.297 ENSMUST00000166873.2
Cdh10
cadherin 10
chr2_+_20737306 2.843 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr11_-_98053415 2.612 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr16_+_45094036 2.395 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr2_+_116067213 2.236 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr15_-_8710734 2.139 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 2.113 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_109251698 2.111 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr17_+_3397189 1.993 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr15_-_66812593 1.540 ENSMUST00000100572.3
Sla
src-like adaptor
chr3_+_62419668 1.497 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr2_-_79456750 1.343 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr2_-_5676046 1.272 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr16_-_97170707 1.272 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr9_+_118478182 1.259 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chrX_-_143933204 1.247 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr9_+_118478344 1.244 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr7_+_126776939 1.242 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr2_-_116067391 1.235 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr15_-_93519499 1.232 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr3_+_68572245 1.212 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr17_-_31636631 1.208 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr6_-_136171722 1.191 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr4_-_45532470 1.190 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr6_-_126645784 1.159 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr2_-_45117349 1.133 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chrX_-_143933089 1.124 ENSMUST00000087313.3
Dcx
doublecortin
chr7_+_35802593 1.123 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr12_+_38780284 1.117 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr9_-_112187766 1.114 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr2_-_7395879 1.104 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr15_+_21111452 1.097 ENSMUST00000075132.6
Cdh12
cadherin 12
chr9_+_113812547 1.086 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr9_-_55919605 1.065 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr17_+_3532554 1.034 ENSMUST00000168560.1
Cldn20
claudin 20
chr5_+_66968416 1.024 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr13_+_42680565 1.015 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr11_-_87359011 1.004 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr8_+_23411490 0.988 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr7_+_126950518 0.983 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr1_-_155417394 0.981 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr6_-_101377897 0.978 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr1_-_78968079 0.945 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr18_-_39487096 0.945 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr4_-_14621805 0.932 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr9_-_96719549 0.929 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr4_+_97777780 0.929 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr13_+_23544052 0.928 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr13_+_23574381 0.926 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr9_-_53975246 0.925 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr9_-_96719404 0.896 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr18_+_37518341 0.891 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr5_+_13398688 0.883 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_172027251 0.859 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chrM_+_10167 0.849 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr16_-_74411292 0.833 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chrM_+_7759 0.831 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr7_+_126950687 0.829 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr3_+_68869563 0.826 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr3_-_66296807 0.814 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr16_-_52296924 0.814 ENSMUST00000167115.1
Alcam
activated leukocyte cell adhesion molecule
chr6_-_57535422 0.807 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr4_+_108719649 0.806 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr12_-_24493656 0.801 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr13_-_85127514 0.801 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr7_+_29071597 0.800 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr19_+_26749726 0.797 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_+_55307743 0.791 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr13_+_94083490 0.777 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chrM_+_9870 0.773 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr4_-_109665249 0.767 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr12_+_38780817 0.758 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr3_-_80802789 0.757 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_-_173276144 0.735 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr8_+_94152607 0.714 ENSMUST00000034211.8
Mt3
metallothionein 3
chr1_-_134955908 0.706 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr18_+_69593361 0.691 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr13_+_23575753 0.690 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr1_-_158356258 0.683 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr8_-_84662841 0.682 ENSMUST00000060427.4
Ier2
immediate early response 2
chr14_-_12345847 0.677 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr7_+_79273201 0.673 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr5_-_62765618 0.672 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr18_+_23415400 0.666 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr5_+_66968559 0.665 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr2_-_45112890 0.660 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr10_+_18469958 0.648 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr1_-_24612700 0.641 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr2_-_86347764 0.639 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr1_-_134955847 0.633 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chrX_+_159708593 0.631 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_-_155417283 0.613 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr15_-_93595877 0.603 ENSMUST00000048982.4
Prickle1
prickle homolog 1 (Drosophila)
chr4_-_155056784 0.601 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr5_-_99252839 0.596 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr16_-_52452465 0.596 ENSMUST00000170035.1
ENSMUST00000164728.1
Alcam

activated leukocyte cell adhesion molecule

chr9_+_32116040 0.588 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr7_-_80405425 0.578 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr1_-_152625212 0.575 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr5_-_124095749 0.571 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr11_+_16752203 0.568 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr8_+_83666827 0.558 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr5_-_131616599 0.553 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr4_-_14621494 0.544 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr6_+_145934113 0.541 ENSMUST00000032383.7
Sspn
sarcospan
chrX_+_163911401 0.533 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr18_+_69344503 0.521 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr16_+_42907563 0.515 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr9_+_35423582 0.511 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr1_+_178529113 0.510 ENSMUST00000161017.1
Kif26b
kinesin family member 26B
chr8_-_106573461 0.507 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr17_-_49564262 0.506 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chrX_+_159697308 0.506 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_+_194619815 0.502 ENSMUST00000027952.5
Plxna2
plexin A2
chr2_+_96318014 0.495 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr5_-_77115145 0.493 ENSMUST00000081964.5
Hopx
HOP homeobox
chr2_-_45110336 0.482 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr3_+_76075583 0.481 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr1_-_132707304 0.474 ENSMUST00000043189.7
Nfasc
neurofascin
chr13_+_21810428 0.467 ENSMUST00000091745.5
Hist1h2ao
histone cluster 1, H2ao
chr4_+_59035088 0.461 ENSMUST00000041160.6
Gng10
guanine nucleotide binding protein (G protein), gamma 10
chr5_+_19907502 0.459 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_+_85432686 0.451 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr2_+_90885860 0.450 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr8_-_31918203 0.443 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr3_-_50443603 0.437 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr15_+_25773985 0.436 ENSMUST00000125667.1
Myo10
myosin X
chr1_+_180109192 0.433 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr4_+_109978004 0.432 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr11_+_103133303 0.426 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr16_-_63864114 0.424 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr12_+_16653470 0.424 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr6_-_97459279 0.421 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr12_+_81631369 0.418 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr14_+_54259227 0.417 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr7_-_19699008 0.409 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr3_-_19264959 0.406 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr14_-_88471396 0.403 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr17_-_29007925 0.399 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr13_+_83732438 0.396 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chrX_-_60893430 0.394 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr11_+_75532099 0.392 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr15_-_67113909 0.391 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr11_+_103133333 0.391 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr12_-_75735729 0.389 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr10_+_127420334 0.387 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr2_+_68104671 0.372 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr3_+_32436376 0.367 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr2_+_23069210 0.361 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr19_-_4698668 0.359 ENSMUST00000177696.1
Gm960
predicted gene 960
chr8_+_107031218 0.357 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr4_-_96553617 0.356 ENSMUST00000030303.5
Cyp2j6
cytochrome P450, family 2, subfamily j, polypeptide 6
chr10_+_127421124 0.354 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr10_+_127420867 0.350 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr13_+_42866247 0.343 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chrX_-_74246534 0.338 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr9_+_54538984 0.337 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr3_+_121953213 0.336 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr1_+_104768510 0.332 ENSMUST00000062528.8
Cdh20
cadherin 20
chr6_+_88724667 0.331 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr12_-_4841583 0.331 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr3_+_121967822 0.329 ENSMUST00000137089.1
Arhgap29
Rho GTPase activating protein 29
chr8_+_54954728 0.328 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr3_-_146770603 0.326 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr7_+_110772604 0.324 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr13_-_23574196 0.324 ENSMUST00000105106.1
Hist1h2bf
histone cluster 1, H2bf
chr18_-_35215008 0.321 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr12_+_74297474 0.317 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr10_+_39612934 0.315 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr17_-_90088343 0.311 ENSMUST00000173917.1
Nrxn1
neurexin I
chr7_+_126950837 0.310 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr19_-_57197435 0.309 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr19_-_4698315 0.307 ENSMUST00000096325.3
Gm960
predicted gene 960
chr5_+_64812336 0.306 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr19_+_25672408 0.304 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chr19_+_44992127 0.303 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr17_+_17402672 0.301 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr4_-_87806296 0.301 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr5_+_63812447 0.299 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr6_-_108185552 0.299 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr1_+_72284367 0.297 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr19_-_57197377 0.297 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr3_+_94398517 0.296 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chr4_-_58553553 0.294 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr2_+_125068118 0.292 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr5_+_19907774 0.291 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_+_25188380 0.291 ENSMUST00000039734.5
Unkl
unkempt-like (Drosophila)
chr4_-_97778042 0.291 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_+_69991633 0.287 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr8_-_67974567 0.284 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chrX_+_112604274 0.280 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr11_-_107337556 0.277 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr14_+_54464141 0.276 ENSMUST00000022782.8
Lrp10
low-density lipoprotein receptor-related protein 10
chr19_-_32196393 0.275 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr12_+_72441852 0.274 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr16_+_43247278 0.273 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr7_-_73541738 0.272 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.8 2.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.8 4.9 GO:0006570 tyrosine metabolic process(GO:0006570)
0.6 1.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.4 1.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.4 1.2 GO:0050975 sensory perception of touch(GO:0050975)
0.4 2.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 3.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.4 1.1 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.1 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.3 1.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.3 1.0 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.3 0.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 1.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 1.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 0.7 GO:0097212 lysosomal membrane organization(GO:0097212)
0.2 0.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 1.5 GO:0019532 oxalate transport(GO:0019532)
0.2 0.6 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.9 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 0.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 1.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 1.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.9 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 1.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 2.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.4 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.1 1.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 1.1 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.1 1.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0061738 abscission(GO:0009838) late endosomal microautophagy(GO:0061738) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0071205 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.6 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.3 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:0061055 myotome development(GO:0061055)
0.1 0.8 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.1 0.8 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.4 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 3.1 GO:0060074 synapse maturation(GO:0060074)
0.1 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 1.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 1.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 1.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 1.2 GO:0001553 luteinization(GO:0001553)
0.1 0.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 4.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.1 GO:0097107 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.2 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 1.0 GO:0046464 neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.1 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.2 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.7 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 0.1 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0033762 response to glucagon(GO:0033762) response to mercury ion(GO:0046689)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.2 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.8 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.4 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.4 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.0 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0009408 response to heat(GO:0009408)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.6 GO:0007632 visual behavior(GO:0007632)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 2.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 1.3 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.0 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.0 GO:0072362 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.4 GO:0019915 lipid storage(GO:0019915)
0.0 0.1 GO:1901898 regulation of cell communication by electrical coupling(GO:0010649) negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 1.1 GO:0060187 cell pole(GO:0060187)
0.3 4.3 GO:0043205 fibril(GO:0043205)
0.2 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 3.2 GO:0005614 interstitial matrix(GO:0005614)
0.2 4.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 0.6 GO:0031983 vesicle lumen(GO:0031983)
0.2 0.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.7 GO:0070688 MLL5-L complex(GO:0070688)
0.1 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 3.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 1.3 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.9 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0034704 calcium channel complex(GO:0034704)
0.0 1.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.5 3.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 1.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 4.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.3 1.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.9 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 1.6 GO:0001618 virus receptor activity(GO:0001618)
0.2 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.6 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 1.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.6 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.1 0.7 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 2.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 2.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 4.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 3.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0070330 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) aromatase activity(GO:0070330)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 3.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0051378 serotonin binding(GO:0051378)
0.1 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.3 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 4.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)