Motif ID: Nr0b1

Z-value: 0.832


Transcription factors associated with Nr0b1:

Gene SymbolEntrez IDGene Name
Nr0b1 ENSMUSG00000025056.4 Nr0b1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_86191782-0.291.5e-01Click!


Activity profile for motif Nr0b1.

activity profile for motif Nr0b1


Sorted Z-values histogram for motif Nr0b1

Sorted Z-values for motif Nr0b1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr0b1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_19094594 4.064 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr5_-_99037035 3.370 ENSMUST00000031277.6
 Prkg2
protein kinase, cGMP-dependent, type II
chr16_-_45844303 3.162 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844228 3.108 ENSMUST00000076333.5
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr17_-_70851189 2.892 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr5_-_99037342 2.871 ENSMUST00000161490.1
 Prkg2
protein kinase, cGMP-dependent, type II
chr13_-_29984219 2.443 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chrX_-_48034842 2.198 ENSMUST00000039026.7
 Apln
apelin
chr7_+_79500081 2.077 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr2_-_54085542 2.076 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr2_-_65238625 1.973 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
 Cobll1


Cobl-like 1


chr1_-_9700209 1.879 ENSMUST00000088658.4
 Mybl1
myeloblastosis oncogene-like 1
chr7_+_79500018 1.780 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr2_+_30066419 1.767 ENSMUST00000067996.6
 Set
SET nuclear oncogene
chr14_+_11553523 1.660 ENSMUST00000022264.6
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr11_+_94328242 1.338 ENSMUST00000021227.5
 Ankrd40
ankyrin repeat domain 40
chr11_+_102604370 1.265 ENSMUST00000057893.5
 Fzd2
frizzled homolog 2 (Drosophila)
chr13_-_64274879 1.221 ENSMUST00000109770.1
 Cdc14b
CDC14 cell division cycle 14B
chr11_+_94327984 1.220 ENSMUST00000107818.2
ENSMUST00000051221.6
 Ankrd40

ankyrin repeat domain 40

chr2_+_71786923 1.205 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr8_-_105707933 1.190 ENSMUST00000013299.9
 Enkd1
enkurin domain containing 1
chr7_-_65371210 1.128 ENSMUST00000102592.3
 Tjp1
tight junction protein 1
chr5_-_115436508 1.127 ENSMUST00000078701.3
 4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr11_-_74723829 1.097 ENSMUST00000102520.2
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chrX_-_145505175 1.063 ENSMUST00000143610.1
 Amot
angiomotin
chr19_-_46039442 0.978 ENSMUST00000137771.1
 Ldb1
LIM domain binding 1
chr13_-_106936907 0.942 ENSMUST00000080856.7
 Ipo11
importin 11
chr17_-_23745829 0.909 ENSMUST00000046525.8
 Kremen2
kringle containing transmembrane protein 2
chr4_-_123750236 0.783 ENSMUST00000102636.3
 Akirin1
akirin 1
chr4_-_132422484 0.741 ENSMUST00000102568.3
 Phactr4
phosphatase and actin regulator 4
chr3_+_86224665 0.731 ENSMUST00000107635.1
 Lrba
LPS-responsive beige-like anchor
chr4_-_132422394 0.723 ENSMUST00000152271.1
ENSMUST00000084170.5
 Phactr4

phosphatase and actin regulator 4

chr15_-_38078842 0.708 ENSMUST00000110336.2
 Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr11_+_105181793 0.700 ENSMUST00000092537.3
ENSMUST00000015107.6
ENSMUST00000145048.1
 Tlk2


tousled-like kinase 2 (Arabidopsis)


chr17_+_29490812 0.684 ENSMUST00000024811.6
 Pim1
proviral integration site 1
chr7_+_82867327 0.616 ENSMUST00000082237.5
 Mex3b
mex3 homolog B (C. elegans)
chr10_-_81350389 0.558 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
 Hmg20b



high mobility group 20B



chr5_+_64803513 0.523 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr15_+_35371498 0.518 ENSMUST00000048646.7
 Vps13b
vacuolar protein sorting 13B (yeast)
chr1_+_140246216 0.514 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
 Kcnt2



potassium channel, subfamily T, member 2



chr17_-_84790517 0.503 ENSMUST00000112308.2
 Lrpprc
leucine-rich PPR-motif containing
chr2_+_157279026 0.498 ENSMUST00000116380.2
 Rpn2
ribophorin II
chr18_+_80046854 0.484 ENSMUST00000070219.7
 Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr2_+_157279065 0.473 ENSMUST00000029171.5
 Rpn2
ribophorin II
chr13_-_14063395 0.459 ENSMUST00000170957.1
 Ggps1
geranylgeranyl diphosphate synthase 1
chr8_-_95434869 0.459 ENSMUST00000034249.6
 Gtl3
gene trap locus 3
chr4_-_138913915 0.446 ENSMUST00000097830.3
 Otud3
OTU domain containing 3
chr14_+_75845296 0.441 ENSMUST00000142061.1
 Tpt1
tumor protein, translationally-controlled 1
chr11_+_23306884 0.431 ENSMUST00000180046.1
 Usp34
ubiquitin specific peptidase 34
chr2_+_129198757 0.425 ENSMUST00000028880.3
 Slc20a1
solute carrier family 20, member 1
chr2_+_85037448 0.423 ENSMUST00000168266.1
ENSMUST00000130729.1
 Ssrp1

structure specific recognition protein 1

chr14_+_70457447 0.404 ENSMUST00000003561.3
 Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr2_+_59160884 0.387 ENSMUST00000037903.8
 Pkp4
plakophilin 4
chr11_+_107547925 0.384 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
 Helz


helicase with zinc finger domain


chr18_-_10030017 0.360 ENSMUST00000116669.1
ENSMUST00000092096.6
 Usp14

ubiquitin specific peptidase 14

chr11_+_105181527 0.349 ENSMUST00000106941.2
 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr16_+_44173239 0.329 ENSMUST00000119746.1
 Gm608
predicted gene 608
chr2_+_4718145 0.310 ENSMUST00000056914.6
 Bend7
BEN domain containing 7
chr17_-_80728026 0.304 ENSMUST00000112389.2
ENSMUST00000025089.7
 Map4k3

mitogen-activated protein kinase kinase kinase kinase 3

chr5_+_110230975 0.283 ENSMUST00000031474.7
ENSMUST00000086674.5
 Ankle2

ankyrin repeat and LEM domain containing 2

chr11_+_23306910 0.281 ENSMUST00000137823.1
 Usp34
ubiquitin specific peptidase 34
chr5_+_121711609 0.278 ENSMUST00000051950.7
 Atxn2
ataxin 2
chr2_-_80581380 0.278 ENSMUST00000111760.2
 Nckap1
NCK-associated protein 1
chr4_-_129696817 0.271 ENSMUST00000102588.3
 Tmem39b
transmembrane protein 39b
chr15_+_80711292 0.268 ENSMUST00000067689.7
 Tnrc6b
trinucleotide repeat containing 6b
chr11_+_50237002 0.262 ENSMUST00000180443.1
 Gm26542
predicted gene, 26542
chr19_+_45015198 0.244 ENSMUST00000179108.1
 Lzts2
leucine zipper, putative tumor suppressor 2
chr10_+_116301374 0.242 ENSMUST00000092167.5
 Ptprb
protein tyrosine phosphatase, receptor type, B
chr10_-_127666673 0.237 ENSMUST00000026469.2
 Nab2
Ngfi-A binding protein 2
chr9_-_110117379 0.201 ENSMUST00000111991.2
ENSMUST00000149199.1
ENSMUST00000035056.7
ENSMUST00000148287.1
ENSMUST00000127744.1
 Dhx30




DEAH (Asp-Glu-Ala-His) box polypeptide 30




chr2_-_80581234 0.198 ENSMUST00000028386.5
 Nckap1
NCK-associated protein 1
chr18_+_35829798 0.185 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr4_-_135971894 0.156 ENSMUST00000105852.1
 Lypla2
lysophospholipase 2
chr5_+_30913398 0.153 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1
chr1_+_42697146 0.122 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr16_+_57121705 0.083 ENSMUST00000166897.1
 Tomm70a
translocase of outer mitochondrial membrane 70 homolog A (yeast)
chr9_-_44881274 0.074 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
 Kmt2a


lysine (K)-specific methyltransferase 2A


chr1_+_59764264 0.063 ENSMUST00000087435.5
 Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr9_-_45984816 0.059 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr12_+_49385174 0.028 ENSMUST00000110746.1
 3110039M20Rik
RIKEN cDNA 3110039M20 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.6 6.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.5 2.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.4 1.5 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4 1.1 GO:0051660 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
0.3 4.1 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.3 2.2 GO:0051461 positive regulation of heat generation(GO:0031652) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.3 1.2 GO:0035878 nail development(GO:0035878)
0.3 1.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.3 1.3 GO:0007223 muscular septum morphogenesis(GO:0003150) Wnt signaling pathway, calcium modulating pathway(GO:0007223) hard palate development(GO:0060022)
0.2 1.0 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 0.7 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.2 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.2 0.6 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 2.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.5 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.1 1.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.5 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.4 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.7 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 1.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.5 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 1.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 2.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.3 GO:0045180 basal cortex(GO:0045180)
0.2 1.1 GO:0000235 astral microtubule(GO:0000235)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 8.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 1.5 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.4 1.1 GO:0043532 angiostatin binding(GO:0043532)
0.3 1.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 1.1 GO:0038132 neuregulin binding(GO:0038132)
0.2 1.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 0.5 GO:0048045 4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.1 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 2.9 GO:0070410 co-SMAD binding(GO:0070410)
0.1 2.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.7 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 2.5 GO:0001047 core promoter binding(GO:0001047)
0.0 0.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 3.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)