Motif ID: Nr1h2

Z-value: 1.039


Transcription factors associated with Nr1h2:

Gene SymbolEntrez IDGene Name
Nr1h2 ENSMUSG00000060601.6 Nr1h2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1h2mm10_v2_chr7_-_44553901_445539550.815.6e-07Click!


Activity profile for motif Nr1h2.

activity profile for motif Nr1h2


Sorted Z-values histogram for motif Nr1h2

Sorted Z-values for motif Nr1h2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_53159885 6.457 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_-_97417730 6.205 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr10_-_109823585 5.373 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr8_-_84773381 4.890 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr6_+_90462562 4.516 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr5_-_100159261 3.552 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr7_-_27446599 3.330 ENSMUST00000011895.7
Sptbn4
spectrin beta, non-erythrocytic 4
chrX_-_53608979 3.161 ENSMUST00000123034.1
Gm14597
predicted gene 14597
chr5_+_123015010 2.850 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr2_-_113829069 2.766 ENSMUST00000024005.7
Scg5
secretogranin V
chr11_+_55098104 2.618 ENSMUST00000000608.7
Gm2a
GM2 ganglioside activator protein
chr2_+_155276297 2.344 ENSMUST00000029128.3
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr1_-_164458345 2.170 ENSMUST00000027863.7
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_+_107331157 2.082 ENSMUST00000031215.8
ENSMUST00000112677.3
Brdt

bromodomain, testis-specific

chr5_-_120588613 2.001 ENSMUST00000046426.8
Tpcn1
two pore channel 1
chr2_+_156420837 1.849 ENSMUST00000103137.3
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr16_+_13940630 1.816 ENSMUST00000141971.1
ENSMUST00000124947.1
ENSMUST00000023360.7
ENSMUST00000143697.1
Mpv17l



Mpv17 transgene, kidney disease mutant-like



chr2_+_156421083 1.760 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
Epb4.1l1


erythrocyte protein band 4.1-like 1


chr18_+_37333853 1.717 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr7_+_112953955 1.708 ENSMUST00000182858.1
Rassf10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr19_+_42247544 1.658 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr11_-_30025915 1.619 ENSMUST00000058902.5
Eml6
echinoderm microtubule associated protein like 6
chr2_+_156421048 1.602 ENSMUST00000109574.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr9_-_63399216 1.594 ENSMUST00000168665.1
2300009A05Rik
RIKEN cDNA 2300009A05 gene
chr3_-_89245829 1.593 ENSMUST00000041022.8
Trim46
tripartite motif-containing 46
chr5_-_136244865 1.590 ENSMUST00000005188.9
Sh2b2
SH2B adaptor protein 2
chr5_-_122779278 1.588 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr8_-_36249292 1.520 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr1_+_57377593 1.502 ENSMUST00000042734.2
1700066M21Rik
RIKEN cDNA 1700066M21 gene
chr15_+_78877172 1.481 ENSMUST00000041587.7
Gga1
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr3_+_62419668 1.465 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr5_+_76840597 1.450 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr4_+_101507947 1.415 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_101507855 1.363 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_+_84179852 1.350 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr4_+_43641262 1.337 ENSMUST00000123351.1
ENSMUST00000128549.1
Npr2

natriuretic peptide receptor 2

chr17_-_56716788 1.268 ENSMUST00000067931.5
Vmac
vimentin-type intermediate filament associated coiled-coil protein
chr2_+_131210501 1.231 ENSMUST00000110206.1
Ap5s1
adaptor-related protein 5 complex, sigma 1 subunit
chr17_-_79715034 1.181 ENSMUST00000024894.1
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr2_+_30266721 1.167 ENSMUST00000113645.1
ENSMUST00000133877.1
ENSMUST00000139719.1
ENSMUST00000113643.1
ENSMUST00000150695.1
Phyhd1




phytanoyl-CoA dioxygenase domain containing 1




chr5_+_117363513 1.155 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr11_+_58963790 1.145 ENSMUST00000075141.6
Trim17
tripartite motif-containing 17
chr16_-_37384915 1.126 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr10_+_21993890 1.120 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr5_+_37185897 1.097 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr2_-_33087169 1.088 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr10_-_67548944 1.066 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr5_-_124327883 1.055 ENSMUST00000031344.6
Mphosph9
M-phase phosphoprotein 9
chr7_+_97453204 1.053 ENSMUST00000050732.7
ENSMUST00000121987.1
Kctd14

potassium channel tetramerisation domain containing 14

chr2_+_155382186 1.037 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr3_-_148989316 1.037 ENSMUST00000098518.2
Lphn2
latrophilin 2
chr4_-_129440800 0.986 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr13_-_12461432 0.980 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
Lgals8



lectin, galactose binding, soluble 8



chr15_+_79895017 0.959 ENSMUST00000023054.7
Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr2_+_155381808 0.898 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr8_+_14095849 0.872 ENSMUST00000152652.1
ENSMUST00000133298.1
Dlgap2

discs, large (Drosophila) homolog-associated protein 2

chr3_+_90514435 0.855 ENSMUST00000048138.6
ENSMUST00000181271.1
S100a13

S100 calcium binding protein A13

chr2_+_102658640 0.850 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_+_84179792 0.840 ENSMUST00000137500.2
ENSMUST00000130012.2
Acaca

acetyl-Coenzyme A carboxylase alpha

chr5_+_26904682 0.834 ENSMUST00000120555.1
Dpp6
dipeptidylpeptidase 6
chr13_+_55600055 0.789 ENSMUST00000133176.1
ENSMUST00000064701.6
B4galt7

xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)

chr15_+_85832301 0.739 ENSMUST00000146088.1
Ttc38
tetratricopeptide repeat domain 38
chr15_+_73724754 0.717 ENSMUST00000163582.1
Ptp4a3
protein tyrosine phosphatase 4a3
chr11_-_101119889 0.675 ENSMUST00000017946.5
Fam134c
family with sequence similarity 134, member C
chr4_-_141538434 0.673 ENSMUST00000078886.3
Spen
SPEN homolog, transcriptional regulator (Drosophila)
chr4_-_141538562 0.648 ENSMUST00000105786.2
Spen
SPEN homolog, transcriptional regulator (Drosophila)
chr11_+_93996082 0.609 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr7_+_49759100 0.602 ENSMUST00000085272.5
Htatip2
HIV-1 tat interactive protein 2, homolog (human)
chr15_+_65787023 0.580 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
Efr3a



EFR3 homolog A (S. cerevisiae)



chr1_+_6214627 0.580 ENSMUST00000027040.6
Rb1cc1
RB1-inducible coiled-coil 1
chr2_+_131491764 0.561 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr11_-_102556122 0.559 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr6_+_124663027 0.553 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr11_-_101119814 0.550 ENSMUST00000107295.3
Fam134c
family with sequence similarity 134, member C
chr2_+_131210363 0.512 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
Ap5s1


adaptor-related protein 5 complex, sigma 1 subunit


chr10_-_81600857 0.468 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
Tle6


transducin-like enhancer of split 6, homolog of Drosophila E(spl)


chr5_-_112392213 0.456 ENSMUST00000031291.7
Asphd2
aspartate beta-hydroxylase domain containing 2
chr12_+_105563123 0.452 ENSMUST00000001652.5
Bdkrb2
bradykinin receptor, beta 2
chr5_+_117357274 0.431 ENSMUST00000031309.9
Wsb2
WD repeat and SOCS box-containing 2
chr7_-_25718976 0.416 ENSMUST00000002683.2
Ccdc97
coiled-coil domain containing 97
chr6_+_54429603 0.410 ENSMUST00000132855.1
ENSMUST00000126637.1
Wipf3

WAS/WASL interacting protein family, member 3

chr16_+_16870829 0.409 ENSMUST00000131063.1
Top3b
topoisomerase (DNA) III beta
chr18_+_59175333 0.399 ENSMUST00000080721.4
Chsy3
chondroitin sulfate synthase 3
chr7_+_81523531 0.385 ENSMUST00000181903.1
2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr7_-_118705708 0.384 ENSMUST00000038791.8
Gde1
glycerophosphodiester phosphodiesterase 1
chr6_+_88902251 0.383 ENSMUST00000055022.8
Tpra1
transmembrane protein, adipocyte asscociated 1
chr2_+_154548888 0.379 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr6_-_99632376 0.372 ENSMUST00000176255.1
Gm20696
predicted gene 20696
chr16_-_37384940 0.365 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr5_+_124328083 0.336 ENSMUST00000111477.1
ENSMUST00000077376.2
2810006K23Rik

RIKEN cDNA 2810006K23 gene

chr2_+_30266513 0.332 ENSMUST00000091132.6
Phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr9_-_42472198 0.331 ENSMUST00000128959.1
ENSMUST00000066148.5
ENSMUST00000138506.1
Tbcel


tubulin folding cofactor E-like


chrX_+_10717451 0.327 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr8_+_18846251 0.295 ENSMUST00000149565.1
ENSMUST00000033847.4
Agpat5

1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)

chr19_-_5845471 0.287 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr11_-_103697898 0.278 ENSMUST00000021329.7
Gosr2
golgi SNAP receptor complex member 2
chr17_+_49428359 0.275 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
Mocs1


molybdenum cofactor synthesis 1


chr3_-_51408925 0.265 ENSMUST00000038108.6
Ndufc1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1
chr7_-_80371197 0.265 ENSMUST00000098346.3
Man2a2
mannosidase 2, alpha 2
chrX_-_155216338 0.260 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr14_-_6973818 0.259 ENSMUST00000166618.1
Gm6356
predicted gene 6356
chr8_+_71592158 0.250 ENSMUST00000034264.4
ENSMUST00000138742.1
ENSMUST00000143441.1
Pgls


6-phosphogluconolactonase


chr5_+_67306941 0.247 ENSMUST00000162372.1
ENSMUST00000113676.2
Slc30a9

solute carrier family 30 (zinc transporter), member 9

chrX_-_8175890 0.245 ENSMUST00000143984.1
Tbc1d25
TBC1 domain family, member 25
chr2_-_164911586 0.206 ENSMUST00000041361.7
Zfp335
zinc finger protein 335
chr4_-_46389391 0.198 ENSMUST00000086563.4
ENSMUST00000030015.5
5830415F09Rik

RIKEN cDNA 5830415F09 gene

chr12_+_87147703 0.198 ENSMUST00000063117.8
Gstz1
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr1_+_58711488 0.194 ENSMUST00000097722.2
ENSMUST00000114313.1
Cflar

CASP8 and FADD-like apoptosis regulator

chr2_-_6951680 0.188 ENSMUST00000076071.2
Gm10115
predicted gene 10115
chr8_+_4238733 0.178 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr17_+_44777127 0.176 ENSMUST00000050630.7
Supt3
suppressor of Ty 3
chr9_+_37208291 0.166 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr2_-_157571270 0.154 ENSMUST00000173378.1
Blcap
bladder cancer associated protein homolog (human)
chr7_+_81523555 0.149 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr8_+_4238815 0.143 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr15_-_89425795 0.142 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr7_+_114768736 0.120 ENSMUST00000117543.1
Insc
inscuteable homolog (Drosophila)
chr17_-_25985641 0.107 ENSMUST00000041641.8
Capn15
calpain 15
chr11_-_60210410 0.099 ENSMUST00000144942.1
Srebf1
sterol regulatory element binding transcription factor 1
chr17_-_35897073 0.092 ENSMUST00000150056.1
ENSMUST00000156817.1
ENSMUST00000146451.1
ENSMUST00000148482.1
2310061I04Rik



RIKEN cDNA 2310061I04 gene



chrX_+_10717390 0.091 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chrX_-_155216444 0.088 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr12_-_87147883 0.069 ENSMUST00000037788.4
Pomt2
protein-O-mannosyltransferase 2
chr5_+_21645813 0.034 ENSMUST00000148873.1
ENSMUST00000072896.6
Armc10

armadillo repeat containing 10

chr4_-_152038568 0.028 ENSMUST00000030792.1
Tas1r1
taste receptor, type 1, member 1
chr8_-_84237042 0.022 ENSMUST00000039480.5
Zswim4
zinc finger SWIM-type containing 4
chr5_-_136565432 0.016 ENSMUST00000176172.1
Cux1
cut-like homeobox 1
chr1_+_132506230 0.013 ENSMUST00000058167.1
Tmem81
transmembrane protein 81
chr9_+_77941274 0.000 ENSMUST00000134072.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0055099 regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.7 2.2 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.6 3.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.5 2.2 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.5 2.6 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.5 2.8 GO:0072318 clathrin coat disassembly(GO:0072318)
0.4 0.9 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.4 1.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.4 1.8 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3 4.9 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 4.5 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 6.3 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.2 2.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.6 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 1.6 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.2 1.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 2.9 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 0.9 GO:0046208 spermine catabolic process(GO:0046208)
0.2 1.0 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 2.1 GO:0007141 male meiosis I(GO:0007141)
0.2 1.0 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.2 0.5 GO:1902219 maintenance of blood-brain barrier(GO:0035633) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 1.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.8 GO:0043206 extracellular fibril organization(GO:0043206)
0.1 0.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 1.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.1 0.2 GO:0014891 striated muscle atrophy(GO:0014891)
0.1 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 0.7 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.3 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 3.9 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 1.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.8 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.3 GO:0008091 spectrin(GO:0008091)
0.4 6.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 1.3 GO:0045098 type III intermediate filament(GO:0045098)
0.3 2.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.6 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 2.3 GO:0000421 autophagosome membrane(GO:0000421)
0.1 4.8 GO:0005776 autophagosome(GO:0005776)
0.1 3.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 8.0 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 5.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.7 2.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.7 2.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 2.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.3 1.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 2.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 1.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.2 2.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 1.2 GO:0070330 aromatase activity(GO:0070330)
0.2 2.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 0.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.6 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 3.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 2.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 2.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.6 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 2.0 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 1.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.3 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 1.1 GO:0030674 protein binding, bridging(GO:0030674)