Motif ID: Nr1h4

Z-value: 0.998


Transcription factors associated with Nr1h4:

Gene SymbolEntrez IDGene Name
Nr1h4 ENSMUSG00000047638.9 Nr1h4



Activity profile for motif Nr1h4.

activity profile for motif Nr1h4


Sorted Z-values histogram for motif Nr1h4

Sorted Z-values for motif Nr1h4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h4

PNG image of the network

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Top targets:


Showing 1 to 20 of 137 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_50752758 4.615 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr4_+_42916647 4.246 ENSMUST00000132173.1
ENSMUST00000107975.1
N28178

expressed sequence N28178

chr10_+_13966268 4.035 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr15_+_80287234 3.455 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr4_+_42917234 3.308 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr9_+_54538984 3.176 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr9_-_106656081 3.130 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr8_+_94179089 2.773 ENSMUST00000034215.6
Mt1
metallothionein 1
chr4_+_133039482 2.727 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr7_+_19176416 2.492 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr7_+_16310412 2.362 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr14_-_26170283 2.305 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr6_-_124769548 2.303 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr2_+_32621750 2.224 ENSMUST00000113278.2
Ak1
adenylate kinase 1
chr7_-_105482197 2.065 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr7_-_4725082 1.985 ENSMUST00000086363.4
ENSMUST00000086364.4
Tmem150b

transmembrane protein 150B

chr1_+_152954966 1.862 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr19_+_44992127 1.790 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr7_+_44442398 1.698 ENSMUST00000058667.8
Lrrc4b
leucine rich repeat containing 4B
chr7_-_47133684 1.631 ENSMUST00000102626.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 3.8 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.2 3.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 3.1 GO:0014047 glutamate secretion(GO:0014047)
0.4 2.8 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.0 2.8 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 2.6 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 2.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.6 2.4 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 2.3 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.4 2.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.7 2.1 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.6 1.9 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 1.9 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 1.9 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 1.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 1.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.5 1.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.4 1.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.3 1.6 GO:2001025 positive regulation of response to drug(GO:2001025)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.8 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.5 4.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 3.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 3.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.7 GO:0045177 apical part of cell(GO:0045177)
0.0 2.4 GO:0072686 mitotic spindle(GO:0072686)
0.5 2.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 2.1 GO:0005901 caveola(GO:0005901)
0.3 1.9 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.9 GO:0005770 late endosome(GO:0005770)
0.0 1.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 1.6 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.5 GO:0097513 myosin II filament(GO:0097513)
0.1 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.5 GO:0010008 endosome membrane(GO:0010008)
0.4 1.3 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.5 4.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.9 3.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 3.5 GO:0051117 ATPase binding(GO:0051117)
0.6 3.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 2.8 GO:0005507 copper ion binding(GO:0005507)
0.0 2.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.5 GO:0005080 protein kinase C binding(GO:0005080)
0.3 2.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 2.0 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.5 1.9 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.3 1.9 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 1.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.3 1.6 GO:0009374 biotin binding(GO:0009374)
0.2 1.5 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 1.5 GO:0019894 kinesin binding(GO:0019894)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)