Motif ID: Nr1i2

Z-value: 0.654


Transcription factors associated with Nr1i2:

Gene SymbolEntrez IDGene Name
Nr1i2 ENSMUSG00000022809.4 Nr1i2



Activity profile for motif Nr1i2.

activity profile for motif Nr1i2


Sorted Z-values histogram for motif Nr1i2

Sorted Z-values for motif Nr1i2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1i2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_136892867 1.710 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr10_-_102490418 1.468 ENSMUST00000020040.3
 Nts
neurotensin
chr7_-_66427469 1.248 ENSMUST00000015278.7
 Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr2_-_25469742 1.190 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr10_-_33995054 1.048 ENSMUST00000164429.1
 Gm17567
predicted gene, 17567
chr1_-_171059390 1.034 ENSMUST00000164044.1
ENSMUST00000169017.1
 Fcgr3

Fc receptor, IgG, low affinity III

chr9_-_53975246 0.987 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chr16_+_91269759 0.974 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr11_+_67586520 0.954 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr1_+_51289106 0.946 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr1_-_162478004 0.934 ENSMUST00000086074.5
ENSMUST00000070330.7
 Dnm3

dynamin 3

chr17_+_55445375 0.913 ENSMUST00000133899.1
ENSMUST00000086878.3
 St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr11_-_6065538 0.898 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr6_+_114131229 0.883 ENSMUST00000032451.7
 Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr9_-_121495678 0.876 ENSMUST00000035120.4
 Cck
cholecystokinin
chr2_+_71528657 0.874 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr16_+_41532999 0.860 ENSMUST00000099761.3
 Lsamp
limbic system-associated membrane protein
chr7_-_110061319 0.856 ENSMUST00000098110.2
 AA474408
expressed sequence AA474408
chr18_+_69345721 0.840 ENSMUST00000078486.6
ENSMUST00000114982.1
 Tcf4

transcription factor 4

chr1_-_21961581 0.788 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
 Kcnq5


potassium voltage-gated channel, subfamily Q, member 5



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 167 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 1.7 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 1.5 GO:0008542 visual learning(GO:0008542)
0.0 1.5 GO:0030041 actin filament polymerization(GO:0030041)
0.1 1.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.4 1.2 GO:0060166 olfactory pit development(GO:0060166)
0.2 1.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 1.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.3 1.0 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 1.0 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 1.0 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 0.9 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.3 0.9 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.1 0.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.9 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.9 GO:0007379 segment specification(GO:0007379)
0.0 0.9 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0072562 blood microparticle(GO:0072562)
0.0 2.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.4 GO:0043679 axon terminus(GO:0043679)
0.1 1.3 GO:0031430 M band(GO:0031430)
0.0 1.3 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 1.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.1 GO:0005901 caveola(GO:0005901)
0.1 1.0 GO:0097433 dense body(GO:0097433)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.2 0.9 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.9 GO:0043203 axon hillock(GO:0043203)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.7 GO:0044316 cone cell pedicle(GO:0044316)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.4 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 1.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 1.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 1.0 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.0 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 0.9 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.3 0.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.3 0.9 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.9 GO:0030552 cAMP binding(GO:0030552)
0.0 0.9 GO:0030674 protein binding, bridging(GO:0030674)
0.2 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)