Motif ID: Nr1i3

Z-value: 1.419


Transcription factors associated with Nr1i3:

Gene SymbolEntrez IDGene Name
Nr1i3 ENSMUSG00000005677.8 Nr1i3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1i3mm10_v2_chr1_+_171213969_171214007-0.144.9e-01Click!


Activity profile for motif Nr1i3.

activity profile for motif Nr1i3


Sorted Z-values histogram for motif Nr1i3

Sorted Z-values for motif Nr1i3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1i3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_166254095 2.998 ENSMUST00000111416.1
 Ildr2
immunoglobulin-like domain containing receptor 2
chr5_-_116422858 2.952 ENSMUST00000036991.4
 Hspb8
heat shock protein 8
chr1_-_163289214 2.543 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1
chr1_+_87264345 2.510 ENSMUST00000118687.1
ENSMUST00000027472.6
 Efhd1

EF hand domain containing 1

chr7_-_30973464 2.507 ENSMUST00000001279.8
 Lsr
lipolysis stimulated lipoprotein receptor
chr11_+_32276400 2.503 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr7_-_30973367 2.437 ENSMUST00000108116.3
 Lsr
lipolysis stimulated lipoprotein receptor
chr10_-_96409038 2.253 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091
chr4_-_137785371 2.207 ENSMUST00000133473.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr7_-_115846080 2.131 ENSMUST00000166207.1
 Sox6
SRY-box containing gene 6
chr7_-_30973399 2.044 ENSMUST00000098553.4
ENSMUST00000147431.1
 Lsr

lipolysis stimulated lipoprotein receptor

chr14_+_46882854 2.017 ENSMUST00000022386.8
ENSMUST00000100672.3
 Samd4

sterile alpha motif domain containing 4

chr9_-_27155418 1.930 ENSMUST00000167074.1
ENSMUST00000034472.8
 Jam3

junction adhesion molecule 3

chr15_+_99006056 1.890 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr1_-_128102412 1.879 ENSMUST00000112538.1
ENSMUST00000086614.5
 Zranb3

zinc finger, RAN-binding domain containing 3

chr10_-_120899067 1.869 ENSMUST00000092143.5
 Msrb3
methionine sulfoxide reductase B3
chr4_-_148087961 1.854 ENSMUST00000030865.8
 Agtrap
angiotensin II, type I receptor-associated protein
chr6_-_72788952 1.808 ENSMUST00000114053.2
 Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr1_+_135729147 1.782 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr16_+_30065333 1.781 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 583 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 7.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.3 5.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 5.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 4.2 GO:0045727 positive regulation of translation(GO:0045727)
0.2 3.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 3.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.7 3.5 GO:0015671 oxygen transport(GO:0015671)
0.2 3.5 GO:0030903 notochord development(GO:0030903)
0.5 3.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.4 3.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 3.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.3 3.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 3.2 GO:0048664 neuron fate determination(GO:0048664)
0.1 3.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 3.0 GO:0070206 protein trimerization(GO:0070206)
0.1 2.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 2.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 2.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 2.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 2.5 GO:0051028 mRNA transport(GO:0051028)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 229 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 18.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 9.4 GO:0031966 mitochondrial membrane(GO:0031966)
1.2 7.0 GO:0061689 tricellular tight junction(GO:0061689)
0.1 6.9 GO:0000922 spindle pole(GO:0000922)
0.1 6.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 6.6 GO:0005657 replication fork(GO:0005657)
0.0 5.4 GO:0005730 nucleolus(GO:0005730)
0.1 4.7 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 4.6 GO:0005925 focal adhesion(GO:0005925)
0.3 4.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 4.1 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 4.1 GO:0005694 chromosome(GO:0005694)
0.0 3.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 3.6 GO:0035371 microtubule plus-end(GO:0035371)
0.1 3.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 3.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 3.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 3.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 3.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 3.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 378 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 7.0 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 6.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 6.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 4.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 4.8 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.7 4.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 4.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 3.9 GO:0030371 translation repressor activity(GO:0030371)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.6 GO:0005178 integrin binding(GO:0005178)
0.7 3.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 3.2 GO:0008013 beta-catenin binding(GO:0008013)
0.8 3.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 3.0 GO:0008432 JUN kinase binding(GO:0008432)
0.0 2.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 2.8 GO:0036310 annealing helicase activity(GO:0036310)
0.0 2.8 GO:0004386 helicase activity(GO:0004386)
0.3 2.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 2.7 GO:0008430 selenium binding(GO:0008430)