Motif ID: Nr2c1

Z-value: 0.700


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_94148023-0.385.5e-02Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 109 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_46991842 2.863 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr9_-_29411736 2.771 ENSMUST00000115236.1
 Ntm
neurotrimin
chr9_-_29412204 2.508 ENSMUST00000115237.1
 Ntm
neurotrimin
chr15_+_80091320 2.394 ENSMUST00000009728.6
ENSMUST00000009727.5
 Syngr1

synaptogyrin 1

chr11_+_75193783 2.088 ENSMUST00000102514.3
 Rtn4rl1
reticulon 4 receptor-like 1
chr9_-_21037775 2.077 ENSMUST00000180870.1
 Gm26592
predicted gene, 26592
chr12_-_83487708 2.067 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr10_+_58813359 1.993 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr11_-_26210553 1.860 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr2_-_29253001 1.795 ENSMUST00000071201.4
 Ntng2
netrin G2
chr15_+_3270767 1.737 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr7_+_46397648 1.653 ENSMUST00000160433.1
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr17_-_35910032 1.619 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
 Atat1




alpha tubulin acetyltransferase 1




chr4_+_133039482 1.546 ENSMUST00000105914.1
 Ahdc1
AT hook, DNA binding motif, containing 1
chr7_+_45896941 1.527 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr1_-_155417283 1.508 ENSMUST00000027741.5
 Xpr1
xenotropic and polytropic retrovirus receptor 1
chr17_-_35909626 1.344 ENSMUST00000141132.1
 Atat1
alpha tubulin acetyltransferase 1
chr1_+_58973521 1.291 ENSMUST00000114296.1
ENSMUST00000027185.4
 Stradb

STE20-related kinase adaptor beta

chr15_-_79141197 1.277 ENSMUST00000169604.1
 1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr7_+_110768169 1.245 ENSMUST00000170374.1
 Ampd3
adenosine monophosphate deaminase 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.3 GO:0010977 negative regulation of neuron projection development(GO:0010977)
1.0 3.0 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 2.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 2.1 GO:0098792 xenophagy(GO:0098792)
0.0 1.9 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.2 1.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 1.7 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 1.6 GO:0031103 axon regeneration(GO:0031103)
0.3 1.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 1.3 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2 1.2 GO:0032264 IMP salvage(GO:0032264)
0.1 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 1.1 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 1.1 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 1.0 GO:0001553 luteinization(GO:0001553)
0.3 0.9 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.3 0.9 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 3.0 GO:0097427 microtubule bundle(GO:0097427)
0.6 2.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 2.1 GO:0071565 nBAF complex(GO:0071565)
0.1 1.7 GO:0030673 axolemma(GO:0030673)
0.1 1.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 0.9 GO:0072534 perineuronal net(GO:0072534)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 2.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 2.1 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 2.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 1.7 GO:0008430 selenium binding(GO:0008430)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 1.5 GO:0001618 virus receptor activity(GO:0001618)
0.2 1.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.2 GO:0005496 steroid binding(GO:0005496)
0.2 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 0.7 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)