Motif ID: Nr2c2

Z-value: 1.126


Transcription factors associated with Nr2c2:

Gene SymbolEntrez IDGene Name
Nr2c2 ENSMUSG00000005893.8 Nr2c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c2mm10_v2_chr6_+_92091378_92091390-0.635.2e-04Click!


Activity profile for motif Nr2c2.

activity profile for motif Nr2c2


Sorted Z-values histogram for motif Nr2c2

Sorted Z-values for motif Nr2c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_38395980 4.765 ENSMUST00000054098.2
 Slc35g1
solute carrier family 35, member G1
chr1_-_138847579 3.929 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr1_+_12718496 3.683 ENSMUST00000088585.3
 Sulf1
sulfatase 1
chr1_-_133424377 3.672 ENSMUST00000153799.1
 Sox13
SRY-box containing gene 13
chr13_-_24761861 3.471 ENSMUST00000006898.3
ENSMUST00000110382.2
 Gmnn

geminin

chr1_+_166254095 3.300 ENSMUST00000111416.1
 Ildr2
immunoglobulin-like domain containing receptor 2
chr11_-_90002881 3.116 ENSMUST00000020864.8
 Pctp
phosphatidylcholine transfer protein
chr10_+_88146992 3.083 ENSMUST00000052355.7
 Nup37
nucleoporin 37
chr7_+_79500081 2.996 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr10_+_88147061 2.935 ENSMUST00000169309.1
 Nup37
nucleoporin 37
chr6_-_95718800 2.796 ENSMUST00000079847.5
 Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr2_+_165655237 2.567 ENSMUST00000063433.7
 Eya2
eyes absent 2 homolog (Drosophila)
chr9_-_99876147 2.486 ENSMUST00000054819.8
 Sox14
SRY-box containing gene 14
chr4_-_97778042 2.442 ENSMUST00000146447.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_+_101419277 2.428 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
 Ak4


adenylate kinase 4


chr10_-_88146867 2.380 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
 Parpbp



PARP1 binding protein



chr10_+_84756055 2.343 ENSMUST00000060397.6
 Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr8_-_91801547 2.248 ENSMUST00000093312.4
 Irx3
Iroquois related homeobox 3 (Drosophila)
chr1_+_132316112 2.237 ENSMUST00000082125.5
ENSMUST00000072177.7
 Nuak2

NUAK family, SNF1-like kinase, 2

chr1_-_163289214 2.227 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 222 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.8 GO:0051028 mRNA transport(GO:0051028)
1.6 4.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.4 4.8 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.3 4.6 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.4 4.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8 3.9 GO:0035262 gonad morphogenesis(GO:0035262)
0.3 3.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.9 3.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 3.7 GO:0007498 mesoderm development(GO:0007498)
0.5 3.5 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 3.5 GO:0015914 phospholipid transport(GO:0015914)
0.2 3.4 GO:0046033 AMP metabolic process(GO:0046033)
0.1 3.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 3.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
1.1 3.2 GO:0030421 defecation(GO:0030421)
0.1 3.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.4 3.1 GO:0015074 DNA integration(GO:0015074)
1.0 3.0 GO:1900211 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594)
0.0 3.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.3 2.8 GO:0006105 succinyl-CoA metabolic process(GO:0006104) succinate metabolic process(GO:0006105)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 115 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.7 GO:0005667 transcription factor complex(GO:0005667)
0.5 6.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 5.3 GO:0000791 euchromatin(GO:0000791)
0.0 4.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 4.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 4.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 3.5 GO:0030496 midbody(GO:0030496)
0.4 2.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.5 2.8 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 2.8 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 2.6 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.7 2.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 2.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.8 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.8 GO:0005657 replication fork(GO:0005657)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 161 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.3 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.5 5.4 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.1 5.3 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 5.0 GO:0004386 helicase activity(GO:0004386)
0.4 4.7 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 4.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
1.4 4.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.4 4.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.7 4.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 4.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.7 3.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 3.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.5 3.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 3.1 GO:0001047 core promoter binding(GO:0001047)
0.0 3.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 2.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.2 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.2 2.1 GO:0034711 inhibin binding(GO:0034711)