Motif ID: Nr2e3

Z-value: 1.154


Transcription factors associated with Nr2e3:

Gene SymbolEntrez IDGene Name
Nr2e3 ENSMUSG00000032292.2 Nr2e3



Activity profile for motif Nr2e3.

activity profile for motif Nr2e3


Sorted Z-values histogram for motif Nr2e3

Sorted Z-values for motif Nr2e3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e3

PNG image of the network

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Top targets:


Showing 1 to 20 of 168 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_141524379 8.024 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr18_-_35215008 6.358 ENSMUST00000091636.3
 Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr1_+_45981548 5.154 ENSMUST00000085632.2
 Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr1_-_52091066 4.854 ENSMUST00000105087.1
 Gm3940
predicted gene 3940
chr6_-_13839916 4.216 ENSMUST00000060442.7
 Gpr85
G protein-coupled receptor 85
chr10_-_109764840 4.025 ENSMUST00000163071.1
 Nav3
neuron navigator 3
chr15_+_85116829 3.987 ENSMUST00000105085.1
 Gm10923
predicted gene 10923
chr3_+_54156039 3.896 ENSMUST00000029311.6
 Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr1_+_19103022 3.695 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr4_-_138396438 3.628 ENSMUST00000105032.2
 Fam43b
family with sequence similarity 43, member B
chr1_-_16770138 3.447 ENSMUST00000071842.8
 Gm5828
predicted gene 5828
chr1_+_185454803 3.276 ENSMUST00000061093.6
 Slc30a10
solute carrier family 30, member 10
chr2_-_45112890 3.228 ENSMUST00000076836.6
 Zeb2
zinc finger E-box binding homeobox 2
chr2_+_65620829 3.139 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr2_+_124610278 3.046 ENSMUST00000051419.8
ENSMUST00000077847.5
ENSMUST00000078621.5
ENSMUST00000076335.5
 Sema6d



sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D



chr13_-_51701041 2.896 ENSMUST00000110042.1
 Gm15440
predicted gene 15440
chr18_+_32938955 2.714 ENSMUST00000042868.4
 Camk4
calcium/calmodulin-dependent protein kinase IV
chr14_+_101840602 2.710 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr1_+_177445660 2.628 ENSMUST00000077225.6
 Zbtb18
zinc finger and BTB domain containing 18
chr16_+_43508118 2.560 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 8.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 7.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 6.9 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.8 6.6 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 5.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 5.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.5 5.0 GO:0042447 hormone catabolic process(GO:0042447)
0.9 4.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 4.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 3.9 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 3.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.4 3.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.5 3.2 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.8 3.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 2.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 2.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.2 2.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 2.7 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 2.5 GO:0097320 membrane tubulation(GO:0097320)
0.6 2.4 GO:1904177 regulation of adipose tissue development(GO:1904177)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.0 GO:0045211 postsynaptic membrane(GO:0045211)
1.3 6.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 5.0 GO:0005811 lipid particle(GO:0005811)
0.1 3.9 GO:0034704 calcium channel complex(GO:0034704)
0.2 3.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 3.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.6 GO:0045171 intercellular bridge(GO:0045171)
0.2 2.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 2.4 GO:0005638 lamin filament(GO:0005638)
0.1 2.3 GO:0042101 T cell receptor complex(GO:0042101)
0.7 2.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 2.2 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.1 GO:0031045 dense core granule(GO:0031045)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 8.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 7.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 6.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 6.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.1 6.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 5.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 5.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.7 5.0 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 4.4 GO:0042805 actinin binding(GO:0042805)
0.1 3.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 3.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 3.0 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 2.6 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 2.5 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 2.4 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 2.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 2.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 2.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.6 2.2 GO:0050436 microfibril binding(GO:0050436)