Motif ID: Nr2e3

Z-value: 1.154


Transcription factors associated with Nr2e3:

Gene SymbolEntrez IDGene Name
Nr2e3 ENSMUSG00000032292.2 Nr2e3



Activity profile for motif Nr2e3.

activity profile for motif Nr2e3


Sorted Z-values histogram for motif Nr2e3

Sorted Z-values for motif Nr2e3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_141524379 8.024 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr18_-_35215008 6.358 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr1_+_45981548 5.154 ENSMUST00000085632.2
Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr1_-_52091066 4.854 ENSMUST00000105087.1
Gm3940
predicted gene 3940
chr6_-_13839916 4.216 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr10_-_109764840 4.025 ENSMUST00000163071.1
Nav3
neuron navigator 3
chr15_+_85116829 3.987 ENSMUST00000105085.1
Gm10923
predicted gene 10923
chr3_+_54156039 3.896 ENSMUST00000029311.6
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr1_+_19103022 3.695 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr4_-_138396438 3.628 ENSMUST00000105032.2
Fam43b
family with sequence similarity 43, member B
chr1_-_16770138 3.447 ENSMUST00000071842.8
Gm5828
predicted gene 5828
chr1_+_185454803 3.276 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr2_-_45112890 3.228 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr2_+_65620829 3.139 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr2_+_124610278 3.046 ENSMUST00000051419.8
ENSMUST00000077847.5
ENSMUST00000078621.5
ENSMUST00000076335.5
Sema6d



sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D



chr13_-_51701041 2.896 ENSMUST00000110042.1
Gm15440
predicted gene 15440
chr18_+_32938955 2.714 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr14_+_101840602 2.710 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr1_+_177445660 2.628 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr16_+_43508118 2.560 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr5_-_104021799 2.549 ENSMUST00000119025.1
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr16_+_43510267 2.491 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr5_-_104021919 2.491 ENSMUST00000031251.9
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr5_+_19227046 2.272 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_-_22850738 2.272 ENSMUST00000092015.4
ENSMUST00000069215.6
Nol4

nucleolar protein 4

chr16_-_22439570 2.270 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr1_+_143640664 2.256 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr16_-_52454074 2.255 ENSMUST00000023312.7
Alcam
activated leukocyte cell adhesion molecule
chr14_+_101840501 2.228 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chrX_-_143933204 2.218 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr12_+_88953399 2.203 ENSMUST00000057634.7
Nrxn3
neurexin III
chr5_+_19907774 2.156 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_19907502 2.132 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_+_68468162 2.053 ENSMUST00000182532.1
Schip1
schwannomin interacting protein 1
chr5_-_34187670 2.038 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chrX_-_143933089 2.017 ENSMUST00000087313.3
Dcx
doublecortin
chr16_-_22439719 2.010 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr17_-_24689901 1.881 ENSMUST00000007236.4
Syngr3
synaptogyrin 3
chr3_-_137981523 1.866 ENSMUST00000136613.1
ENSMUST00000029806.6
Dapp1

dual adaptor for phosphotyrosine and 3-phosphoinositides 1

chr4_-_151861762 1.822 ENSMUST00000097774.2
Camta1
calmodulin binding transcription activator 1
chr11_+_111066154 1.818 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_-_151861698 1.817 ENSMUST00000049790.7
Camta1
calmodulin binding transcription activator 1
chr10_+_90576570 1.795 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chrX_+_163911401 1.775 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr8_+_125995102 1.773 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr1_-_97977233 1.762 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr13_-_34963788 1.743 ENSMUST00000164155.1
ENSMUST00000021853.5
Eci3

enoyl-Coenzyme A delta isomerase 3

chr18_+_37819543 1.739 ENSMUST00000055935.5
Pcdhga9
protocadherin gamma subfamily A, 9
chr5_-_99252839 1.715 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr9_+_113812547 1.637 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr8_-_54718664 1.561 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr1_+_146420434 1.556 ENSMUST00000163646.1
Gm5263
predicted gene 5263
chr11_-_42182924 1.542 ENSMUST00000020707.5
ENSMUST00000132971.1
Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chrX_+_166344692 1.536 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr10_+_90576252 1.490 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr12_+_95695350 1.455 ENSMUST00000110117.1
Flrt2
fibronectin leucine rich transmembrane protein 2
chr1_-_40790642 1.453 ENSMUST00000039672.5
Mfsd9
major facilitator superfamily domain containing 9
chr3_-_144202300 1.409 ENSMUST00000121796.1
ENSMUST00000121112.1
Lmo4

LIM domain only 4

chr13_+_21478907 1.358 ENSMUST00000062609.5
Zkscan4
zinc finger with KRAB and SCAN domains 4
chr10_+_90576777 1.341 ENSMUST00000183136.1
ENSMUST00000182595.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr5_+_76809964 1.338 ENSMUST00000120818.1
C530008M17Rik
RIKEN cDNA C530008M17 gene
chr15_+_81872309 1.324 ENSMUST00000023116.6
Aco2
aconitase 2, mitochondrial
chr3_+_76074270 1.312 ENSMUST00000038364.8
Fstl5
follistatin-like 5
chr10_-_29144194 1.308 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr10_+_90576678 1.301 ENSMUST00000182284.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_77347816 1.295 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr16_+_31422268 1.293 ENSMUST00000089759.2
Bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr14_+_123659971 1.278 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr12_-_34528844 1.270 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr4_+_102760294 1.262 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr4_+_102760135 1.231 ENSMUST00000066824.7
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr2_+_96318014 1.227 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr10_+_62071014 1.222 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr3_-_88503331 1.221 ENSMUST00000029699.6
Lmna
lamin A
chr4_-_151861667 1.198 ENSMUST00000169423.2
Camta1
calmodulin binding transcription activator 1
chr10_-_109009055 1.178 ENSMUST00000156979.1
Syt1
synaptotagmin I
chr17_+_75178797 1.170 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr3_-_88503187 1.132 ENSMUST00000120377.1
Lmna
lamin A
chr14_+_76504185 1.096 ENSMUST00000177207.1
Tsc22d1
TSC22 domain family, member 1
chr2_-_136387929 1.067 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr10_+_90576708 1.061 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chr14_+_76504478 1.056 ENSMUST00000022587.9
ENSMUST00000134109.1
Tsc22d1

TSC22 domain family, member 1

chr13_-_28953690 1.052 ENSMUST00000067230.5
Sox4
SRY-box containing gene 4
chr17_+_75178911 1.047 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr7_-_110862944 1.043 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr3_-_123690806 1.040 ENSMUST00000154668.1
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_+_180111339 1.037 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr12_+_69963452 1.034 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr8_-_111910171 1.015 ENSMUST00000034430.4
Chst5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr9_-_77347787 1.007 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr8_-_13200576 0.999 ENSMUST00000165605.2
Grtp1
GH regulated TBC protein 1
chr10_-_109010955 0.968 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr11_-_3774706 0.964 ENSMUST00000155197.1
Osbp2
oxysterol binding protein 2
chr1_-_58424042 0.947 ENSMUST00000034868.7
Clk1
CDC-like kinase 1
chr19_+_46328179 0.945 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chr13_-_12464925 0.888 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr10_+_127705170 0.828 ENSMUST00000079590.5
Myo1a
myosin IA
chr16_+_23107754 0.782 ENSMUST00000077605.5
ENSMUST00000115341.3
Eif4a2

eukaryotic translation initiation factor 4A2

chrX_-_59166080 0.769 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr17_-_17624458 0.766 ENSMUST00000041047.2
Lnpep
leucyl/cystinyl aminopeptidase
chr11_-_65162904 0.757 ENSMUST00000093002.5
ENSMUST00000047463.8
Arhgap44

Rho GTPase activating protein 44

chr19_-_29753600 0.717 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr4_+_143412920 0.717 ENSMUST00000132915.1
ENSMUST00000037356.7
Pramef8

PRAME family member 8

chr5_+_88583527 0.713 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr4_-_109665249 0.711 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr14_+_13453937 0.691 ENSMUST00000153954.1
Synpr
synaptoporin
chr10_+_107271827 0.645 ENSMUST00000020057.8
ENSMUST00000105280.3
Lin7a

lin-7 homolog A (C. elegans)

chr11_-_68957445 0.603 ENSMUST00000108671.1
Arhgef15
Rho guanine nucleotide exchange factor (GEF) 15
chr18_+_61555308 0.554 ENSMUST00000165721.1
ENSMUST00000115246.2
ENSMUST00000166990.1
ENSMUST00000163205.1
ENSMUST00000170862.1
Csnk1a1




casein kinase 1, alpha 1




chr7_+_27731373 0.547 ENSMUST00000108336.1
Zfp60
zinc finger protein 60
chr4_+_143413002 0.535 ENSMUST00000155157.1
Pramef8
PRAME family member 8
chr9_-_13245741 0.527 ENSMUST00000110582.2
Jrkl
jerky homolog-like (mouse)
chr7_+_27731445 0.517 ENSMUST00000042641.7
Zfp60
zinc finger protein 60
chr18_+_61555258 0.512 ENSMUST00000165123.1
Csnk1a1
casein kinase 1, alpha 1
chr11_-_76571527 0.509 ENSMUST00000072740.6
Abr
active BCR-related gene
chr11_+_70018728 0.500 ENSMUST00000018700.6
ENSMUST00000134376.2
Dlg4

discs, large homolog 4 (Drosophila)

chr3_-_96220880 0.485 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr4_+_49521176 0.455 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chr7_+_27731398 0.441 ENSMUST00000130997.1
Zfp60
zinc finger protein 60
chr14_+_13454010 0.432 ENSMUST00000112656.2
Synpr
synaptoporin
chr9_-_77347889 0.422 ENSMUST00000185039.1
Mlip
muscular LMNA-interacting protein
chr1_+_151755339 0.421 ENSMUST00000059498.5
Edem3
ER degradation enhancer, mannosidase alpha-like 3
chr15_+_6299797 0.404 ENSMUST00000159046.1
ENSMUST00000161040.1
Dab2

disabled 2, mitogen-responsive phosphoprotein

chr11_+_115765420 0.404 ENSMUST00000093912.4
ENSMUST00000136720.1
ENSMUST00000103034.3
ENSMUST00000141871.1
2310067B10Rik



RIKEN cDNA 2310067B10 gene



chr16_-_16560201 0.401 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr16_-_44016387 0.399 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr2_+_24949747 0.394 ENSMUST00000028350.3
Zmynd19
zinc finger, MYND domain containing 19
chrX_+_120290259 0.391 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
Pcdh11x


protocadherin 11 X-linked


chr13_+_80883403 0.374 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3
chr8_-_60954726 0.353 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr11_+_94044111 0.349 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr4_-_154636831 0.348 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr14_+_20674311 0.338 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr2_-_73660351 0.333 ENSMUST00000154258.1
Chn1
chimerin (chimaerin) 1
chr7_+_83584910 0.327 ENSMUST00000039317.7
ENSMUST00000164944.1
Tmc3

transmembrane channel-like gene family 3

chr11_+_19924403 0.325 ENSMUST00000093298.5
Spred2
sprouty-related, EVH1 domain containing 2
chr16_+_32271468 0.321 ENSMUST00000093183.3
Smco1
single-pass membrane protein with coiled-coil domains 1
chr5_-_123140135 0.315 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr15_+_6299781 0.314 ENSMUST00000078019.6
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr2_-_73660401 0.306 ENSMUST00000102677.4
Chn1
chimerin (chimaerin) 1
chr5_-_8997324 0.288 ENSMUST00000003720.4
Crot
carnitine O-octanoyltransferase
chr4_-_43040279 0.286 ENSMUST00000107958.1
ENSMUST00000107959.1
ENSMUST00000152846.1
Fam214b


family with sequence similarity 214, member B


chr2_-_161109017 0.254 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr11_-_109472611 0.248 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr5_+_136987019 0.235 ENSMUST00000004968.4
Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr2_+_69647208 0.224 ENSMUST00000074963.2
ENSMUST00000112286.2
Bbs5

Bardet-Biedl syndrome 5 (human)

chr3_+_118430299 0.219 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr5_-_24447587 0.212 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr1_+_83159733 0.209 ENSMUST00000113436.1
ENSMUST00000065436.3
ENSMUST00000065403.6
Daw1


dynein assembly factor with WDR repeat domains 1


chr11_-_42182163 0.203 ENSMUST00000153147.1
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr2_-_27027909 0.185 ENSMUST00000102890.4
ENSMUST00000153388.1
ENSMUST00000045702.5
Slc2a6


solute carrier family 2 (facilitated glucose transporter), member 6


chrX_+_42149534 0.180 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr12_-_31950210 0.169 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr5_-_51553896 0.166 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr11_+_19924354 0.153 ENSMUST00000093299.6
Spred2
sprouty-related, EVH1 domain containing 2
chrX_-_134111852 0.139 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr1_+_97770158 0.132 ENSMUST00000112844.3
ENSMUST00000112842.1
ENSMUST00000027571.6
Gin1


gypsy retrotransposon integrase 1


chrX_-_108834303 0.106 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr11_+_110997487 0.069 ENSMUST00000106635.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr9_-_57645561 0.066 ENSMUST00000034863.6
Csk
c-src tyrosine kinase
chr3_-_90695706 0.056 ENSMUST00000069960.5
ENSMUST00000117167.1
S100a9

S100 calcium binding protein A9 (calgranulin B)

chr19_-_7341433 0.044 ENSMUST00000165965.1
ENSMUST00000051711.9
ENSMUST00000169541.1
ENSMUST00000165989.1
Mark2



MAP/microtubule affinity-regulating kinase 2



chr10_-_11080956 0.034 ENSMUST00000105560.1
Grm1
glutamate receptor, metabotropic 1
chr8_+_79028317 0.013 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr3_+_103279293 0.007 ENSMUST00000029444.6
ENSMUST00000106860.1
Trim33

tripartite motif-containing 33

chr10_+_119992962 0.006 ENSMUST00000154238.1
Grip1
glutamate receptor interacting protein 1
chr7_-_87493371 0.004 ENSMUST00000004770.5
Tyr
tyrosinase
chr13_-_91388079 0.002 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.8 6.6 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.8 8.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.8 3.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.6 2.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.6 7.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.5 3.2 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 5.0 GO:0042447 hormone catabolic process(GO:0042447)
0.4 3.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.4 1.8 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.4 1.8 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.4 1.1 GO:0003289 atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 6.9 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.3 1.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 4.2 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 1.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 3.9 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 0.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 1.6 GO:0005513 detection of calcium ion(GO:0005513)
0.2 1.7 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 2.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 1.8 GO:0009404 toxin metabolic process(GO:0009404)
0.2 2.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.7 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 5.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.7 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.1 2.2 GO:0090129 regulation of synapse maturation(GO:0090128) positive regulation of synapse maturation(GO:0090129)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.4 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388) synaptic vesicle lumen acidification(GO:0097401)
0.1 0.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 2.1 GO:0001553 luteinization(GO:0001553)
0.1 0.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 2.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 1.7 GO:0071711 basement membrane organization(GO:0071711)
0.1 1.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 2.5 GO:0097320 membrane tubulation(GO:0097320)
0.1 2.2 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.1 0.4 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 1.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 2.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.2 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.1 5.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 1.0 GO:0007097 nuclear migration(GO:0007097)
0.1 1.0 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.6 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.3 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 3.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 1.9 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.9 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 1.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.7 2.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.5 1.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 2.4 GO:0005638 lamin filament(GO:0005638)
0.2 2.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 3.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 2.1 GO:0031045 dense core granule(GO:0031045)
0.1 2.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.9 GO:0071437 invadopodium(GO:0071437)
0.1 1.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.1 GO:0045095 keratin filament(GO:0045095)
0.1 5.0 GO:0005811 lipid particle(GO:0005811)
0.1 3.9 GO:0034704 calcium channel complex(GO:0034704)
0.1 2.2 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 16.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 3.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 1.1 GO:0097440 apical dendrite(GO:0097440)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0014704 intercalated disc(GO:0014704)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.0 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.0 GO:0042641 actomyosin(GO:0042641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 8.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.1 6.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.7 5.0 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.6 1.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.6 2.2 GO:0050436 microfibril binding(GO:0050436)
0.4 1.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.4 6.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 1.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.3 1.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 6.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 2.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 2.4 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 2.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 4.4 GO:0042805 actinin binding(GO:0042805)
0.1 7.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.1 3.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 3.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 3.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) voltage-gated proton channel activity(GO:0030171)
0.0 1.0 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 5.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 2.5 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 5.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 3.0 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 2.6 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 1.5 GO:0017124 SH3 domain binding(GO:0017124)