Motif ID: Nr2f2

Z-value: 0.717


Transcription factors associated with Nr2f2:

Gene SymbolEntrez IDGene Name
Nr2f2 ENSMUSG00000030551.7 Nr2f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f2mm10_v2_chr7_-_70360593_70360746-0.067.8e-01Click!


Activity profile for motif Nr2f2.

activity profile for motif Nr2f2


Sorted Z-values histogram for motif Nr2f2

Sorted Z-values for motif Nr2f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_94875600 1.485 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr10_-_9675163 1.444 ENSMUST00000100070.2
 Samd5
sterile alpha motif domain containing 5
chr5_-_92278155 1.423 ENSMUST00000159345.1
ENSMUST00000113102.3
 Naaa

N-acylethanolamine acid amidase

chr2_+_102658640 1.299 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr13_-_34652671 1.279 ENSMUST00000053459.7
 Pxdc1
PX domain containing 1
chr11_-_98053415 1.118 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr17_-_71526819 1.046 ENSMUST00000024851.9
 Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr3_+_121723515 1.001 ENSMUST00000029771.8
 F3
coagulation factor III
chr17_-_31277327 0.995 ENSMUST00000024832.7
 Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr7_-_135716374 0.981 ENSMUST00000033310.7
 Mki67
antigen identified by monoclonal antibody Ki 67
chr9_-_54661666 0.912 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_-_54661870 0.901 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr3_-_116712198 0.899 ENSMUST00000120120.1
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr12_-_57546121 0.891 ENSMUST00000044380.6
 Foxa1
forkhead box A1
chr1_+_9547948 0.882 ENSMUST00000144177.1
 Adhfe1
alcohol dehydrogenase, iron containing, 1
chr13_-_99900645 0.860 ENSMUST00000022150.6
 Cartpt
CART prepropeptide
chr13_+_15463202 0.849 ENSMUST00000130065.1
 Gli3
GLI-Kruppel family member GLI3
chr1_-_82586781 0.846 ENSMUST00000087050.5
 Col4a4
collagen, type IV, alpha 4
chr10_+_93641041 0.838 ENSMUST00000020204.4
 Ntn4
netrin 4
chr3_-_116711820 0.831 ENSMUST00000153108.1
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 2.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.5 1.4 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 1.4 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 1.4 GO:0051608 histamine transport(GO:0051608)
0.2 1.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.3 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 1.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 1.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.3 1.0 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.1 1.0 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0 1.0 GO:0035082 axoneme assembly(GO:0035082)
0.3 0.9 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.3 0.9 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.3 0.8 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.3 0.8 GO:1904956 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 1.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.3 1.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 1.0 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 1.0 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.2 0.8 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.8 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.8 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 0.5 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.2 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 1.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.4 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.3 1.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 1.2 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 1.0 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 0.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)