Motif ID: Nr2f6

Z-value: 0.661


Transcription factors associated with Nr2f6:

Gene SymbolEntrez IDGene Name
Nr2f6 ENSMUSG00000002393.8 Nr2f6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f6mm10_v2_chr8_-_71381907_71381977-0.038.8e-01Click!


Activity profile for motif Nr2f6.

activity profile for motif Nr2f6


Sorted Z-values histogram for motif Nr2f6

Sorted Z-values for motif Nr2f6



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f6

PNG image of the network

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Top targets:


Showing 1 to 20 of 133 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_85205120 2.455 ENSMUST00000107188.3
 Sh3gl2
SH3-domain GRB2-like 2
chr4_+_85205417 2.256 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
 Sh3gl2


SH3-domain GRB2-like 2


chr11_+_32283511 2.101 ENSMUST00000093209.3
 Hba-a1
hemoglobin alpha, adult chain 1
chr8_+_71469186 1.791 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
 Dda1


DET1 and DDB1 associated 1


chr7_+_45896941 1.775 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr10_-_79984227 1.678 ENSMUST00000052885.7
 Tmem259
transmembrane protein 259
chr10_+_93589413 1.661 ENSMUST00000181835.1
 4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr10_-_79983970 1.595 ENSMUST00000124536.1
 Tmem259
transmembrane protein 259
chr9_-_124424154 1.576 ENSMUST00000180270.1
 Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr3_+_121967822 1.548 ENSMUST00000137089.1
 Arhgap29
Rho GTPase activating protein 29
chr7_+_45897429 1.434 ENSMUST00000140243.1
 Tmem143
transmembrane protein 143
chr5_-_137741601 1.362 ENSMUST00000119498.1
ENSMUST00000061789.7
 Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr7_-_28766469 1.298 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr17_-_35910032 1.152 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
 Atat1




alpha tubulin acetyltransferase 1




chr4_+_97777606 1.110 ENSMUST00000075448.6
ENSMUST00000092532.6
 Nfia

nuclear factor I/A

chr4_+_97777780 1.040 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
 Nfia


nuclear factor I/A


chr7_-_30232186 1.019 ENSMUST00000006254.5
 Tbcb
tubulin folding cofactor B
chr16_-_4624984 1.015 ENSMUST00000014445.6
 Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr15_-_95528702 1.003 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr2_+_25242227 0.984 ENSMUST00000154498.1
 Rnf208
ring finger protein 208

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 3.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.2 3.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 2.3 GO:0060074 synapse maturation(GO:0060074)
0.0 2.2 GO:0048821 erythrocyte development(GO:0048821)
0.7 2.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 1.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.6 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 1.4 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.2 1.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.3 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 1.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 1.0 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.1 0.9 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.8 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.8 GO:0034340 response to type I interferon(GO:0034340)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 2.1 GO:0097427 microtubule bundle(GO:0097427)
0.3 1.0 GO:1990879 CST complex(GO:1990879)
0.2 1.0 GO:0031314 mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.9 GO:0061574 ASAP complex(GO:0061574)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.3 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 2.1 GO:0005496 steroid binding(GO:0005496)
0.1 1.6 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 1.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.5 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.5 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.5 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)