Motif ID: Nr5a2

Z-value: 1.168


Transcription factors associated with Nr5a2:

Gene SymbolEntrez IDGene Name
Nr5a2 ENSMUSG00000026398.8 Nr5a2



Activity profile for motif Nr5a2.

activity profile for motif Nr5a2


Sorted Z-values histogram for motif Nr5a2

Sorted Z-values for motif Nr5a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr5a2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_21787218 10.273 ENSMUST00000091751.2
 Hist1h2an
histone cluster 1, H2an
chr1_-_51941261 8.624 ENSMUST00000097103.3
 Gm8420
predicted gene 8420
chr1_+_45981548 8.465 ENSMUST00000085632.2
 Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr1_-_52091066 8.223 ENSMUST00000105087.1
 Gm3940
predicted gene 3940
chrX_-_141874870 7.941 ENSMUST00000182079.1
 Gm15294
predicted gene 15294
chr15_+_85116829 7.015 ENSMUST00000105085.1
 Gm10923
predicted gene 10923
chr13_-_21753851 5.702 ENSMUST00000074752.2
 Hist1h2ak
histone cluster 1, H2ak
chr7_-_46179929 5.510 ENSMUST00000033123.6
 Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr12_+_12911986 5.325 ENSMUST00000085720.1
 Rpl36-ps3
ribosomal protein L36, pseudogene 3
chr8_+_124793061 5.178 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr8_+_124793013 5.128 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr12_-_34291092 4.665 ENSMUST00000166546.2
 Gm18025
predicted gene, 18025
chr13_-_22042949 4.400 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr18_+_45268876 3.945 ENSMUST00000183850.1
ENSMUST00000066890.7
 Kcnn2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

chr1_-_134235420 3.556 ENSMUST00000038191.6
ENSMUST00000086465.4
 Adora1

adenosine A1 receptor

chr3_-_107517321 3.425 ENSMUST00000166892.1
 Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr13_-_21501418 3.290 ENSMUST00000044043.2
 Gm11273
predicted gene 11273
chr1_+_181352618 3.281 ENSMUST00000161880.1
ENSMUST00000027795.7
 Cnih3

cornichon homolog 3 (Drosophila)

chr13_+_21787461 3.262 ENSMUST00000110473.2
ENSMUST00000102982.1
 Hist1h2bp

histone cluster 1, H2bp

chr2_+_178119166 3.213 ENSMUST00000108916.1
 Phactr3
phosphatase and actin regulator 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 104 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 25.6 GO:0006342 chromatin silencing(GO:0006342)
0.4 10.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 7.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
1.8 7.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 7.1 GO:0006334 nucleosome assembly(GO:0006334)
0.2 5.2 GO:0010043 response to zinc ion(GO:0010043)
1.6 4.8 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.0 4.7 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 4.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.2 4.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 4.2 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 3.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
1.2 3.6 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.7 3.4 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 3.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5 3.2 GO:0046103 inosine biosynthetic process(GO:0046103)
0.1 3.2 GO:0001893 maternal placenta development(GO:0001893)
1.0 3.0 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0 3.0 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
1.0 2.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.1 GO:0000790 nuclear chromatin(GO:0000790)
0.2 8.1 GO:0000786 nucleosome(GO:0000786)
0.4 7.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 6.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 5.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 5.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 4.1 GO:0005604 basement membrane(GO:0005604)
0.3 3.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 3.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 3.8 GO:0005884 actin filament(GO:0005884)
0.1 3.7 GO:0005844 polysome(GO:0005844)
0.0 3.6 GO:0008021 synaptic vesicle(GO:0008021)
0.1 3.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 3.2 GO:0001520 outer dense fiber(GO:0001520)
0.6 3.0 GO:0042583 chromaffin granule(GO:0042583)
0.1 3.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 2.7 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.5 GO:0016363 nuclear matrix(GO:0016363)
0.3 2.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 2.4 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 8.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 7.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 6.7 GO:0005267 potassium channel activity(GO:0005267)
0.2 4.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.1 4.3 GO:0004111 creatine kinase activity(GO:0004111)
0.2 4.2 GO:0035613 RNA stem-loop binding(GO:0035613)
1.0 3.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 3.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.5 3.6 GO:0032795 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.2 3.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 3.4 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 3.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 3.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.5 3.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.0 2.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.0 2.9 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 2.9 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.2 2.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)