Motif ID: Nr6a1

Z-value: 0.440


Transcription factors associated with Nr6a1:

Gene SymbolEntrez IDGene Name
Nr6a1 ENSMUSG00000063972.7 Nr6a1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr6a1mm10_v2_chr2_-_38926217_389264540.442.5e-02Click!


Activity profile for motif Nr6a1.

activity profile for motif Nr6a1


Sorted Z-values histogram for motif Nr6a1

Sorted Z-values for motif Nr6a1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr6a1

PNG image of the network

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Top targets:


Showing 1 to 20 of 70 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_30314810 1.184 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
 Syne4



spectrin repeat containing, nuclear envelope family member 4



chr7_-_66427469 0.898 ENSMUST00000015278.7
 Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr11_-_60811228 0.892 ENSMUST00000018744.8
 Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr12_+_3807017 0.804 ENSMUST00000020991.8
ENSMUST00000172509.1
 Dnmt3a

DNA methyltransferase 3A

chr13_-_24761440 0.778 ENSMUST00000176890.1
ENSMUST00000175689.1
 Gmnn

geminin

chr14_+_12189943 0.763 ENSMUST00000119888.1
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr2_+_172472512 0.744 ENSMUST00000029007.2
 Fam209
family with sequence similarity 209
chr6_+_83349446 0.635 ENSMUST00000136501.1
 Bola3
bolA-like 3 (E. coli)
chr12_+_3807076 0.621 ENSMUST00000174817.1
 Dnmt3a
DNA methyltransferase 3A
chr1_-_151428440 0.609 ENSMUST00000064771.5
 Swt1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr1_+_131970589 0.583 ENSMUST00000027695.6
 Slc45a3
solute carrier family 45, member 3
chr5_-_137610626 0.557 ENSMUST00000142675.1
 Pcolce
procollagen C-endopeptidase enhancer protein
chr5_-_30073554 0.544 ENSMUST00000026846.6
 Tyms
thymidylate synthase
chr18_-_77767752 0.493 ENSMUST00000048192.7
 Haus1
HAUS augmin-like complex, subunit 1
chr15_-_73184840 0.461 ENSMUST00000044113.10
 Ago2
argonaute RISC catalytic subunit 2
chr8_+_75109528 0.452 ENSMUST00000164309.1
 Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr5_-_5694024 0.429 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
 Steap2



six transmembrane epithelial antigen of prostate 2



chr9_-_50603792 0.397 ENSMUST00000000175.4
 Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr5_-_5694559 0.391 ENSMUST00000115426.2
 Steap2
six transmembrane epithelial antigen of prostate 2
chr3_+_138526174 0.388 ENSMUST00000029803.7
 Eif4e
eukaryotic translation initiation factor 4E

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.4 GO:0009177 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.2 1.4 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 1.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 0.9 GO:0060166 olfactory pit development(GO:0060166)
0.3 0.8 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.2 0.6 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.5 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.4 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.2 GO:0009838 abscission(GO:0009838)
0.1 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0001741 XY body(GO:0001741)
0.1 1.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.4 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 1.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.3 0.9 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905)
0.2 0.9 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.9 GO:0016504 peptidase activator activity(GO:0016504)
0.3 0.8 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.6 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0005542 folic acid binding(GO:0005542)
0.1 0.4 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.4 GO:0015035 glutathione peroxidase activity(GO:0004602) protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.0 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)