Motif ID: Olig2_Olig3

Z-value: 0.916

Transcription factors associated with Olig2_Olig3:

Gene SymbolEntrez IDGene Name
Olig2 ENSMUSG00000039830.8 Olig2
Olig3 ENSMUSG00000045591.5 Olig3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Olig3mm10_v2_chr10_+_19356558_193565650.517.2e-03Click!
Olig2mm10_v2_chr16_+_91225550_91225579-0.087.0e-01Click!


Activity profile for motif Olig2_Olig3.

activity profile for motif Olig2_Olig3


Sorted Z-values histogram for motif Olig2_Olig3

Sorted Z-values for motif Olig2_Olig3



Network of associatons between targets according to the STRING database.



First level regulatory network of Olig2_Olig3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_92164666 6.746 ENSMUST00000183123.1
ENSMUST00000182033.1
 Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr9_-_119825456 4.459 ENSMUST00000070617.7
 Scn11a
sodium channel, voltage-gated, type XI, alpha
chr3_-_154330543 4.426 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr11_+_32276400 4.329 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr16_+_16213318 4.201 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
 Pkp2


plakophilin 2


chr1_+_12692430 4.067 ENSMUST00000180062.1
ENSMUST00000177608.1
 Sulf1

sulfatase 1

chr3_-_63851251 3.446 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
 Plch1


phospholipase C, eta 1


chr4_+_15957923 3.300 ENSMUST00000029879.8
ENSMUST00000149069.1
 Nbn

nibrin

chr19_-_53589067 3.292 ENSMUST00000095978.3
 Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr1_-_186117251 3.291 ENSMUST00000045388.7
 Lyplal1
lysophospholipase-like 1
chr16_-_44558864 3.201 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr16_-_44558879 3.043 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr10_-_22149270 3.013 ENSMUST00000179054.1
ENSMUST00000069372.6
 E030030I06Rik

RIKEN cDNA E030030I06 gene

chr17_-_62606679 2.852 ENSMUST00000163332.1
 Efna5
ephrin A5
chr1_+_51987139 2.708 ENSMUST00000168302.1
 Stat4
signal transducer and activator of transcription 4
chr7_+_30314810 2.601 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
 Syne4



spectrin repeat containing, nuclear envelope family member 4



chr2_-_105399286 2.580 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr3_+_125404072 2.549 ENSMUST00000173932.1
 Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr5_-_100820929 2.376 ENSMUST00000117364.1
ENSMUST00000055245.6
 Fam175a

family with sequence similarity 175, member A

chr11_-_9011111 2.365 ENSMUST00000020683.3
 Hus1
Hus1 homolog (S. pombe)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 136 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.9 4.3 GO:0015671 oxygen transport(GO:0015671)
1.4 4.2 GO:0002159 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
1.0 4.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 3.5 GO:0016042 lipid catabolic process(GO:0016042)
0.7 3.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.7 3.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 3.3 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.2 2.9 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 2.5 GO:0032526 response to retinoic acid(GO:0032526)
0.8 2.4 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 2.4 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 2.4 GO:0021884 forebrain neuron development(GO:0021884)
0.3 2.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 2.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 2.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.5 2.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 2.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 2.0 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 1.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.2 GO:0044295 axonal growth cone(GO:0044295)
0.5 5.4 GO:0030057 desmosome(GO:0030057)
1.5 4.5 GO:0044299 C-fiber(GO:0044299)
0.7 4.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.5 4.3 GO:0005833 hemoglobin complex(GO:0005833)
0.5 3.3 GO:0030870 Mre11 complex(GO:0030870)
0.3 2.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 2.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.4 2.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 2.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.6 1.7 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.7 GO:0005775 vacuolar lumen(GO:0005775)
0.2 1.7 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.6 GO:0072562 blood microparticle(GO:0072562)
0.2 1.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.4 1.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.3 GO:0030894 replisome(GO:0030894)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.9 4.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 4.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.8 4.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 3.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 3.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 3.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 3.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 2.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.6 2.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 2.1 GO:0016428 tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 2.1 GO:0051015 actin filament binding(GO:0051015)
0.7 2.0 GO:0043532 angiostatin binding(GO:0043532)
0.2 2.0 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.2 1.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 1.7 GO:0008494 translation activator activity(GO:0008494)
0.2 1.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.7 GO:0005537 mannose binding(GO:0005537)
0.1 1.7 GO:0045295 gamma-catenin binding(GO:0045295)