Motif ID: Onecut1_Cux2

Z-value: 1.073

Transcription factors associated with Onecut1_Cux2:

Gene SymbolEntrez IDGene Name
Cux2 ENSMUSG00000042589.12 Cux2
Cux2 ENSMUSG00000072641.1 Cux2
Onecut1 ENSMUSG00000043013.9 Onecut1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Onecut1mm10_v2_chr9_+_74861888_748619210.715.5e-05Click!
Cux2mm10_v2_chr5_-_122049822_122049882-0.252.1e-01Click!


Activity profile for motif Onecut1_Cux2.

activity profile for motif Onecut1_Cux2


Sorted Z-values histogram for motif Onecut1_Cux2

Sorted Z-values for motif Onecut1_Cux2



Network of associatons between targets according to the STRING database.



First level regulatory network of Onecut1_Cux2

PNG image of the network

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Top targets:


Showing 1 to 20 of 101 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 10.994 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr3_+_102010138 7.025 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr6_+_4755327 5.409 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr2_-_148046896 4.625 ENSMUST00000172928.1
ENSMUST00000047315.3
 Foxa2

forkhead box A2

chr14_+_68083853 4.557 ENSMUST00000022639.7
 Nefl
neurofilament, light polypeptide
chr8_-_91801547 3.095 ENSMUST00000093312.4
 Irx3
Iroquois related homeobox 3 (Drosophila)
chr7_+_25152456 2.957 ENSMUST00000098678.1
 D930028M14Rik
RIKEN cDNA D930028M14 gene
chr1_-_89933290 2.918 ENSMUST00000036954.7
 Gbx2
gastrulation brain homeobox 2
chr19_+_55894508 2.636 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr10_-_64090241 1.666 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr12_+_55598917 1.578 ENSMUST00000051857.3
 Insm2
insulinoma-associated 2
chr10_-_64090265 1.529 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr8_+_58911755 1.448 ENSMUST00000062978.6
 BC030500
cDNA sequence BC030500
chr12_-_46818749 1.435 ENSMUST00000021438.6
 Nova1
neuro-oncological ventral antigen 1
chr11_+_120232921 1.415 ENSMUST00000122148.1
ENSMUST00000044985.7
 Bahcc1

BAH domain and coiled-coil containing 1

chr4_+_62965560 1.368 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
 Zfp618


zinc finger protein 618


chr14_-_55092277 1.301 ENSMUST00000036328.8
 Zfhx2
zinc finger homeobox 2
chr3_+_5218589 1.297 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr2_-_168767136 1.297 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr3_+_5218516 1.277 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 11.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 7.0 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 5.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
1.5 4.6 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
1.5 4.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 3.2 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 3.1 GO:0007498 mesoderm development(GO:0007498)
0.4 2.9 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.3 2.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 2.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.3 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 1.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.2 1.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 1.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 0.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.8 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.5 GO:0007262 STAT protein import into nucleus(GO:0007262)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 4.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 4.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 2.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 2.4 GO:0000792 heterochromatin(GO:0000792)
0.1 1.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.1 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.4 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 10.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 7.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 4.6 GO:0043274 phospholipase binding(GO:0043274)
0.1 4.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 3.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 1.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.1 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 1.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)