Motif ID: Osr2_Osr1

Z-value: 0.792

Transcription factors associated with Osr2_Osr1:

Gene SymbolEntrez IDGene Name
Osr1 ENSMUSG00000048387.7 Osr1
Osr2 ENSMUSG00000022330.4 Osr2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Osr1mm10_v2_chr12_+_9574437_95744480.086.9e-01Click!


Activity profile for motif Osr2_Osr1.

activity profile for motif Osr2_Osr1


Sorted Z-values histogram for motif Osr2_Osr1

Sorted Z-values for motif Osr2_Osr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Osr2_Osr1

PNG image of the network

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Top targets:


Showing 1 to 20 of 170 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_170010744 3.708 ENSMUST00000178789.1
 Gm21887
predicted gene, 21887
chrY_+_90785442 3.187 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr10_-_109823585 1.389 ENSMUST00000161582.1
 Nav3
neuron navigator 3
chr4_+_13743424 1.167 ENSMUST00000006761.3
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_43163891 0.993 ENSMUST00000008280.7
 Fhl2
four and a half LIM domains 2
chr4_-_134254076 0.925 ENSMUST00000060050.5
 Grrp1
glycine/arginine rich protein 1
chrY_+_90784738 0.911 ENSMUST00000179483.1
 Erdr1
erythroid differentiation regulator 1
chr5_+_107497718 0.814 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr15_-_43869993 0.801 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr7_+_126950687 0.784 ENSMUST00000106333.1
 Sez6l2
seizure related 6 homolog like 2
chr4_+_43383449 0.770 ENSMUST00000135216.1
ENSMUST00000152322.1
 Rusc2

RUN and SH3 domain containing 2

chr10_+_4611971 0.714 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr7_-_57509995 0.711 ENSMUST00000068456.6
 Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr5_+_107497762 0.707 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr8_+_12984246 0.693 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
 Mcf2l


mcf.2 transforming sequence-like


chr7_+_44849581 0.653 ENSMUST00000150335.1
ENSMUST00000107882.1
 Akt1s1

AKT1 substrate 1 (proline-rich)

chr2_-_80128834 0.644 ENSMUST00000102654.4
ENSMUST00000102655.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr15_-_78718113 0.632 ENSMUST00000088592.4
 Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr3_-_127225847 0.603 ENSMUST00000182726.1
ENSMUST00000182779.1
 Ank2

ankyrin 2, brain

chr6_-_59024470 0.567 ENSMUST00000089860.5
 Fam13a
family with sequence similarity 13, member A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.9 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 1.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 1.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.8 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0 0.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.8 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.2 0.7 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214) innervation(GO:0060384)
0.1 0.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.6 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.2 0.5 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.2 0.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) glutamate secretion, neurotransmission(GO:0061535)
0.1 0.4 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.4 GO:0006537 glutamate biosynthetic process(GO:0006537) proline biosynthetic process(GO:0006561)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0031430 M band(GO:0031430)
0.1 1.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.2 0.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.2 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.4 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)