Motif ID: Pax2

Z-value: 0.737


Transcription factors associated with Pax2:

Gene SymbolEntrez IDGene Name
Pax2 ENSMUSG00000004231.9 Pax2



Activity profile for motif Pax2.

activity profile for motif Pax2


Sorted Z-values histogram for motif Pax2

Sorted Z-values for motif Pax2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_135212557 2.230 ENSMUST00000062893.7
 Cenpe
centromere protein E
chr3_+_159495408 1.646 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
 Depdc1a


DEP domain containing 1a


chr5_-_106458440 1.640 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr10_-_45470201 1.426 ENSMUST00000079390.6
 Lin28b
lin-28 homolog B (C. elegans)
chrX_+_36328353 1.286 ENSMUST00000016383.3
 Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr4_-_129189512 1.123 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
 S100pbp


S100P binding protein


chr4_-_129189600 1.092 ENSMUST00000117497.1
ENSMUST00000117350.1
 S100pbp

S100P binding protein

chr1_-_82291370 1.087 ENSMUST00000069799.2
 Irs1
insulin receptor substrate 1
chr2_-_28916412 1.058 ENSMUST00000050776.2
ENSMUST00000113849.1
 Barhl1

BarH-like 1 (Drosophila)

chr4_-_129189646 1.046 ENSMUST00000106059.1
 S100pbp
S100P binding protein
chr6_-_6217023 1.041 ENSMUST00000015256.8
 Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr5_-_100500592 1.019 ENSMUST00000149714.1
ENSMUST00000046154.5
 Lin54

lin-54 homolog (C. elegans)

chr11_-_76846968 1.018 ENSMUST00000021201.5
 Cpd
carboxypeptidase D
chr11_+_35769462 0.994 ENSMUST00000018990.7
 Pank3
pantothenate kinase 3
chr6_+_7555053 0.987 ENSMUST00000090679.2
ENSMUST00000184986.1
 Tac1

tachykinin 1

chr2_+_84839395 0.971 ENSMUST00000146816.1
ENSMUST00000028469.7
 Slc43a1

solute carrier family 43, member 1

chr6_+_113531675 0.961 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr10_+_88091070 0.960 ENSMUST00000048621.7
 Pmch
pro-melanin-concentrating hormone
chr2_+_75659253 0.945 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
 Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr9_-_91365756 0.922 ENSMUST00000034927.6
 Zic1
zinc finger protein of the cerebellum 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0030901 midbrain development(GO:0030901)
0.4 2.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.6 1.8 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 1.6 GO:0001709 cell fate determination(GO:0001709)
0.1 1.5 GO:0060746 parental behavior(GO:0060746)
0.0 1.5 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.2 1.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 1.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 1.4 GO:0051028 mRNA transport(GO:0051028)
0.4 1.3 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.1 1.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 1.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.3 1.0 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.3 1.0 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.3 1.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.3 1.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.0 GO:0042117 monocyte activation(GO:0042117)
0.2 1.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) mitotic spindle midzone(GO:1990023)
0.1 2.0 GO:0090544 BAF-type complex(GO:0090544)
0.4 1.3 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.2 1.2 GO:0097422 tubular endosome(GO:0097422)
0.0 1.2 GO:0000502 proteasome complex(GO:0000502)
0.4 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.6 GO:0001740 Barr body(GO:0001740)
0.0 0.6 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 3.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.6 2.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 2.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3 1.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 1.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.2 GO:0030332 cyclin binding(GO:0030332)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.1 1.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 1.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 0.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)