Motif ID: Pax3

Z-value: 0.442


Transcription factors associated with Pax3:

Gene SymbolEntrez IDGene Name
Pax3 ENSMUSG00000004872.9 Pax3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax3mm10_v2_chr1_-_78196832_78196845-0.376.2e-02Click!


Activity profile for motif Pax3.

activity profile for motif Pax3


Sorted Z-values histogram for motif Pax3

Sorted Z-values for motif Pax3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax3

PNG image of the network

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Top targets:


Showing 1 to 20 of 37 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_40346290 1.043 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr12_+_38780284 0.701 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr2_+_168230597 0.671 ENSMUST00000099071.3
 Mocs3
molybdenum cofactor synthesis 3
chr12_+_38780817 0.653 ENSMUST00000160856.1
 Etv1
ets variant gene 1
chrX_+_159840463 0.607 ENSMUST00000112451.1
ENSMUST00000112453.2
 Sh3kbp1

SH3-domain kinase binding protein 1

chr12_+_38781093 0.602 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr4_+_127077374 0.599 ENSMUST00000046751.6
ENSMUST00000094713.3
 Zmym6

zinc finger, MYM-type 6

chr8_+_33428709 0.588 ENSMUST00000059351.7
 5930422O12Rik
RIKEN cDNA 5930422O12 gene
chrX_+_114474312 0.559 ENSMUST00000113371.1
ENSMUST00000040504.5
 Klhl4

kelch-like 4

chr2_-_136387929 0.552 ENSMUST00000035264.2
ENSMUST00000077200.3
 Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr10_+_82138253 0.523 ENSMUST00000105314.2
 AU041133
expressed sequence AU041133
chr3_-_59262825 0.505 ENSMUST00000050360.7
 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr14_+_51893610 0.461 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chrX_-_103623648 0.454 ENSMUST00000156211.1
 Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr1_+_176814660 0.444 ENSMUST00000056773.8
ENSMUST00000027785.8
 Sdccag8

serologically defined colon cancer antigen 8

chr19_-_36736653 0.424 ENSMUST00000087321.2
 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr18_+_35562158 0.410 ENSMUST00000166793.1
 Matr3
matrin 3
chr7_+_120843551 0.392 ENSMUST00000106489.1
ENSMUST00000143279.1
 Eef2k

eukaryotic elongation factor-2 kinase

chr7_+_30121915 0.380 ENSMUST00000098596.3
ENSMUST00000153792.1
 Zfp382

zinc finger protein 382

chrX_-_103623704 0.378 ENSMUST00000130063.1
ENSMUST00000125419.1
 Ftx

Ftx transcript, Xist regulator (non-protein coding)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.8 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.2 0.7 GO:0018307 enzyme active site formation(GO:0018307)
0.2 0.5 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0 0.2 GO:0071638 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)

Gene overrepresentation in cellular_component category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular_function category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)