Motif ID: Pax5

Z-value: 1.286


Transcription factors associated with Pax5:

Gene SymbolEntrez IDGene Name
Pax5 ENSMUSG00000014030.9 Pax5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5mm10_v2_chr4_-_44710408_447104180.252.2e-01Click!


Activity profile for motif Pax5.

activity profile for motif Pax5


Sorted Z-values histogram for motif Pax5

Sorted Z-values for motif Pax5



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_152982240 3.135 ENSMUST00000044278.5
 St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr11_-_102897123 2.886 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr15_-_79164477 2.729 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr16_+_45094036 2.237 ENSMUST00000061050.5
 Ccdc80
coiled-coil domain containing 80
chr16_+_45093611 2.109 ENSMUST00000099498.2
 Ccdc80
coiled-coil domain containing 80
chr19_-_57008187 2.090 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr3_+_90537242 2.078 ENSMUST00000098911.3
 S100a16
S100 calcium binding protein A16
chr3_+_90537306 2.069 ENSMUST00000107335.1
 S100a16
S100 calcium binding protein A16
chr11_-_102897146 2.040 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr4_-_64046925 2.007 ENSMUST00000107377.3
 Tnc
tenascin C
chr9_+_37367354 1.952 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr13_-_71963713 1.897 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr2_-_162661075 1.885 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
 Ptprt



protein tyrosine phosphatase, receptor type, T



chr10_+_127725392 1.654 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr5_+_89027959 1.630 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr16_-_37384915 1.615 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr14_+_45219993 1.553 ENSMUST00000146150.1
 Gpr137c
G protein-coupled receptor 137C
chr14_+_54936456 1.530 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr1_+_50927511 1.409 ENSMUST00000081851.3
 Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr11_-_69560186 1.361 ENSMUST00000004036.5
 Efnb3
ephrin B3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 312 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 4.8 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.3 4.0 GO:0070842 aggresome assembly(GO:0070842)
0.2 3.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 3.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 3.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 2.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 2.7 GO:0048484 enteric nervous system development(GO:0048484)
0.1 2.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 2.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 2.5 GO:0051592 response to calcium ion(GO:0051592)
0.2 2.2 GO:0090527 actin filament reorganization(GO:0090527)
0.7 2.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 2.0 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.6 1.9 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.3 1.9 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2 1.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.9 GO:0007616 long-term memory(GO:0007616)
0.3 1.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.6 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.6 GO:0010172 embryonic body morphogenesis(GO:0010172)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 6.4 GO:0005614 interstitial matrix(GO:0005614)
1.2 4.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 3.0 GO:0030027 lamellipodium(GO:0030027)
0.0 2.7 GO:0031201 SNARE complex(GO:0031201)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.3 2.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 2.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.2 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.2 GO:0043218 compact myelin(GO:0043218)
0.2 1.1 GO:0044308 axonal spine(GO:0044308)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 185 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 4.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 3.8 GO:0017137 Rab GTPase binding(GO:0017137)
1.0 3.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 2.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 2.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 2.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 2.0 GO:0045545 syndecan binding(GO:0045545)
0.2 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.9 GO:0050693 LBD domain binding(GO:0050693)
0.2 1.9 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.7 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 1.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 1.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 1.4 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)