Motif ID: Pax8

Z-value: 0.342


Transcription factors associated with Pax8:

Gene SymbolEntrez IDGene Name
Pax8 ENSMUSG00000026976.9 Pax8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax8mm10_v2_chr2_-_24475097_24475215-0.096.5e-01Click!


Activity profile for motif Pax8.

activity profile for motif Pax8


Sorted Z-values histogram for motif Pax8

Sorted Z-values for motif Pax8



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_66852017 0.770 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr18_-_66860458 0.587 ENSMUST00000057942.2
 Mc4r
melanocortin 4 receptor
chr7_-_42578588 0.467 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr7_+_6961160 0.420 ENSMUST00000054055.6
 Usp29
ubiquitin specific peptidase 29
chr13_-_25270076 0.258 ENSMUST00000057866.6
 Nrsn1
neurensin 1
chr11_+_78499087 0.246 ENSMUST00000017488.4
 Vtn
vitronectin
chr1_+_6487231 0.226 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr13_+_65512678 0.199 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chrX_-_105391770 0.168 ENSMUST00000136406.1
ENSMUST00000150604.1
 5330434G04Rik

RIKEN cDNA 5330434G04 gene

chrX_-_7572843 0.162 ENSMUST00000132788.1
 Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr13_-_62777089 0.138 ENSMUST00000167516.2
 Gm5141
predicted gene 5141
chrX_-_105391726 0.136 ENSMUST00000142109.1
 5330434G04Rik
RIKEN cDNA 5330434G04 gene
chr19_+_46075842 0.127 ENSMUST00000165017.1
 Nolc1
nucleolar and coiled-body phosphoprotein 1
chr4_+_103313806 0.121 ENSMUST00000035780.3
 Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr4_+_6191093 0.114 ENSMUST00000029907.5
 Ubxn2b
UBX domain protein 2B
chr7_-_29906087 0.108 ENSMUST00000053521.8
 Zfp27
zinc finger protein 27
chr4_+_59805829 0.104 ENSMUST00000030080.6
 Snx30
sorting nexin family member 30
chr9_-_103230415 0.104 ENSMUST00000035158.9
 Trf
transferrin
chr11_-_69801716 0.102 ENSMUST00000011285.4
ENSMUST00000102585.1
 Fgf11

fibroblast growth factor 11

chr17_+_45555693 0.099 ENSMUST00000024742.7
 Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr7_+_114768736 0.096 ENSMUST00000117543.1
 Insc
inscuteable homolog (Drosophila)
chr13_-_62607499 0.096 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr9_+_109052828 0.095 ENSMUST00000124432.1
 Shisa5
shisa homolog 5 (Xenopus laevis)
chr16_-_17125106 0.092 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr18_-_12121460 0.074 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
 Tmem241


transmembrane protein 241


chr11_+_24080664 0.070 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr2_+_128967383 0.062 ENSMUST00000110320.2
ENSMUST00000110319.2
 Zc3h6

zinc finger CCCH type containing 6

chr1_+_64690443 0.056 ENSMUST00000114077.1
 Ccnyl1
cyclin Y-like 1
chr8_-_64849818 0.055 ENSMUST00000034017.7
 Klhl2
kelch-like 2, Mayven
chr16_-_30587537 0.039 ENSMUST00000117363.2
 Lsg1
large subunit GTPase 1 homolog (S. cerevisiae)
chr9_+_32116040 0.037 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr12_+_71048338 0.034 ENSMUST00000135709.1
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr1_+_65186727 0.026 ENSMUST00000097707.4
ENSMUST00000081154.7
 Pikfyve

phosphoinositide kinase, FYVE finger containing

chr16_+_34784917 0.021 ENSMUST00000023538.8
 Mylk
myosin, light polypeptide kinase
chr13_-_62520451 0.014 ENSMUST00000082203.6
ENSMUST00000101547.4
 Zfp934

zinc finger protein 934

chr7_+_12897800 0.012 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
 Zscan22



zinc finger and SCAN domain containing 22



chr17_+_21691860 0.012 ENSMUST00000072133.4
 Gm10226
predicted gene 10226

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0097421 liver regeneration(GO:0097421)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)