Motif ID: Pbx2

Z-value: 0.620


Transcription factors associated with Pbx2:

Gene SymbolEntrez IDGene Name
Pbx2 ENSMUSG00000034673.8 Pbx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pbx2mm10_v2_chr17_+_34592248_34592329-0.653.4e-04Click!


Activity profile for motif Pbx2.

activity profile for motif Pbx2


Sorted Z-values histogram for motif Pbx2

Sorted Z-values for motif Pbx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pbx2

PNG image of the network

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Top targets:


Showing 1 to 20 of 138 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_11227511 3.736 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr15_-_66812593 2.903 ENSMUST00000100572.3
 Sla
src-like adaptor
chr15_+_21111452 2.259 ENSMUST00000075132.6
 Cdh12
cadherin 12
chr2_+_65620829 1.793 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr2_-_104257400 1.625 ENSMUST00000141159.1
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chr6_+_8259288 1.613 ENSMUST00000159335.1
 Gm16039
predicted gene 16039
chr1_-_56972437 1.502 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr11_+_3330781 1.302 ENSMUST00000136536.1
ENSMUST00000093399.4
 Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr2_+_128967383 1.252 ENSMUST00000110320.2
ENSMUST00000110319.2
 Zc3h6

zinc finger CCCH type containing 6

chr11_+_3330401 1.231 ENSMUST00000045153.4
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr9_+_112234257 1.218 ENSMUST00000149308.3
ENSMUST00000144424.2
ENSMUST00000139552.2
 2900079G21Rik


RIKEN cDNA 2900079G21 gene


chr15_+_92597104 1.215 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr6_+_8259327 1.215 ENSMUST00000159378.1
 Gm16039
predicted gene 16039
chr6_+_8259379 1.207 ENSMUST00000162034.1
ENSMUST00000160705.1
ENSMUST00000159433.1
 Gm16039


predicted gene 16039


chr3_+_121953213 1.205 ENSMUST00000037958.7
ENSMUST00000128366.1
 Arhgap29

Rho GTPase activating protein 29

chr11_-_110095937 1.122 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr3_-_152982240 0.912 ENSMUST00000044278.5
 St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr8_+_72646679 0.907 ENSMUST00000161386.1
ENSMUST00000093427.4
 Nwd1

NACHT and WD repeat domain containing 1

chr18_+_37725706 0.840 ENSMUST00000066149.6
 Pcdhga9
protocadherin gamma subfamily A, 9
chrX_+_134295225 0.838 ENSMUST00000037687.7
 Tmem35
transmembrane protein 35

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 2.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 1.8 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 1.6 GO:0098792 xenophagy(GO:0098792)
0.1 1.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.1 0.8 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0001553 luteinization(GO:0001553)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.4 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.3 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 2.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 1.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.6 GO:0030553 cGMP binding(GO:0030553)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.4 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)