Motif ID: Pgr_Nr3c1

Z-value: 0.528

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39489880_39489915-0.339.5e-02Click!


Activity profile for motif Pgr_Nr3c1.

activity profile for motif Pgr_Nr3c1


Sorted Z-values histogram for motif Pgr_Nr3c1

Sorted Z-values for motif Pgr_Nr3c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 134 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 1.950 ENSMUST00000075312.3
 Ttr
transthyretin
chr10_+_97565436 1.933 ENSMUST00000038160.4
 Lum
lumican
chr4_-_44710408 1.593 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
 Pax5









paired box gene 5









chr9_+_91368970 0.873 ENSMUST00000172646.1
 Zic4
zinc finger protein of the cerebellum 4
chr9_+_91368811 0.856 ENSMUST00000173054.1
 Zic4
zinc finger protein of the cerebellum 4
chr19_+_55894508 0.735 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr14_-_124677089 0.665 ENSMUST00000095529.3
 Fgf14
fibroblast growth factor 14
chr2_-_180776749 0.648 ENSMUST00000061098.2
 Bhlhe23
basic helix-loop-helix family, member e23
chr2_+_65620829 0.627 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr14_+_99298652 0.605 ENSMUST00000005279.6
 Klf5
Kruppel-like factor 5
chr4_-_136898803 0.582 ENSMUST00000046285.5
 C1qa
complement component 1, q subcomponent, alpha polypeptide
chr14_-_16575456 0.545 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr17_-_68004075 0.466 ENSMUST00000024840.5
 Arhgap28
Rho GTPase activating protein 28
chr5_+_24364804 0.453 ENSMUST00000030834.4
ENSMUST00000115090.1
 Nos3

nitric oxide synthase 3, endothelial cell

chr13_-_84064772 0.441 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr10_-_109010955 0.415 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr10_-_116473418 0.411 ENSMUST00000087965.4
ENSMUST00000164271.1
 Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr11_-_83649349 0.391 ENSMUST00000001008.5
 Ccl3
chemokine (C-C motif) ligand 3
chr9_-_49798729 0.381 ENSMUST00000166811.2
 Ncam1
neural cell adhesion molecule 1
chr2_-_162661075 0.350 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
 Ptprt



protein tyrosine phosphatase, receptor type, T




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 1.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.6 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.8 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.7 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 0.7 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 0.6 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 0.6 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.5 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.5 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 0.4 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.3 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 0.7 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)
0.1 0.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.0 GO:0031673 H zone(GO:0031673)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.1 1.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)