Motif ID: Plag1

Z-value: 0.902


Transcription factors associated with Plag1:

Gene SymbolEntrez IDGene Name
Plag1 ENSMUSG00000003282.3 Plag1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plag1mm10_v2_chr4_-_3938354_3938401-0.882.5e-09Click!


Activity profile for motif Plag1.

activity profile for motif Plag1


Sorted Z-values histogram for motif Plag1

Sorted Z-values for motif Plag1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plag1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_133498538 5.408 ENSMUST00000125541.1
 Trnp1
TMF1-regulated nuclear protein 1
chr4_-_129121699 4.154 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
 Hpca


hippocalcin


chr5_+_117841839 3.888 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr15_-_78544345 3.259 ENSMUST00000053239.2
 Sstr3
somatostatin receptor 3
chr7_-_27446599 3.163 ENSMUST00000011895.7
 Sptbn4
spectrin beta, non-erythrocytic 4
chr5_+_117781017 3.067 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr4_-_129121889 2.852 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
 Hpca


hippocalcin


chr10_+_58813359 2.811 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr1_-_56969827 2.674 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr11_+_77930800 2.656 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr16_-_18622403 2.651 ENSMUST00000167388.1
 Gp1bb
glycoprotein Ib, beta polypeptide
chr15_-_66801577 2.591 ENSMUST00000168589.1
 Sla
src-like adaptor
chr10_-_102490418 2.548 ENSMUST00000020040.3
 Nts
neurotensin
chr1_-_56969864 2.534 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr4_-_129121234 2.489 ENSMUST00000030572.3
 Hpca
hippocalcin
chr4_+_130308595 2.468 ENSMUST00000070532.7
 Fabp3
fatty acid binding protein 3, muscle and heart
chr5_-_37717122 2.371 ENSMUST00000094836.4
 Stk32b
serine/threonine kinase 32B
chr11_+_74619594 2.370 ENSMUST00000100866.2
 E130309D14Rik
RIKEN cDNA E130309D14 gene
chr7_-_46099752 2.359 ENSMUST00000180081.1
 Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr13_-_14523178 2.267 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 322 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.3 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
3.2 9.5 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.3 8.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
1.7 7.0 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.4 7.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 5.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.8 4.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.7 4.6 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.3 3.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 3.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 3.3 GO:0010107 potassium ion import(GO:0010107)
0.1 3.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.4 3.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.0 2.9 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 2.8 GO:0033344 cholesterol efflux(GO:0033344)
0.1 2.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.6 2.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3 2.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 2.4 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 2.4 GO:0002021 response to dietary excess(GO:0002021)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 136 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 10.7 GO:0044327 dendritic spine head(GO:0044327)
0.2 9.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 8.2 GO:0097060 synaptic membrane(GO:0097060)
1.0 6.2 GO:0008091 spectrin(GO:0008091)
0.6 6.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.9 4.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 4.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 4.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 3.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 3.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 3.3 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 3.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 2.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.7 GO:0097440 apical dendrite(GO:0097440)
0.8 2.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 2.5 GO:0034704 calcium channel complex(GO:0034704)
0.1 2.4 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 219 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.3 7.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 5.9 GO:0005509 calcium ion binding(GO:0005509)
0.8 4.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 4.5 GO:0030506 ankyrin binding(GO:0030506)
0.6 4.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 3.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 3.7 GO:0035497 cAMP response element binding(GO:0035497)
0.2 3.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.1 3.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 3.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 3.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 3.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.9 GO:0003924 GTPase activity(GO:0003924)
0.1 2.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 2.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.6 2.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.5 2.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 2.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)