Motif ID: Plagl1

Z-value: 0.695


Transcription factors associated with Plagl1:

Gene SymbolEntrez IDGene Name
Plagl1 ENSMUSG00000019817.12 Plagl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plagl1mm10_v2_chr10_+_13090788_13090843-0.822.5e-07Click!


Activity profile for motif Plagl1.

activity profile for motif Plagl1


Sorted Z-values histogram for motif Plagl1

Sorted Z-values for motif Plagl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plagl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 113 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_152338619 2.614 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr2_-_104257400 2.563 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr6_-_91807424 2.452 ENSMUST00000162300.1
Grip2
glutamate receptor interacting protein 2
chr17_+_46297406 2.377 ENSMUST00000061722.6
ENSMUST00000166280.1
Dlk2

delta-like 2 homolog (Drosophila)

chr5_-_139130159 2.152 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr6_-_91807318 2.109 ENSMUST00000159684.1
Grip2
glutamate receptor interacting protein 2
chr6_+_4504814 1.800 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr19_+_6497772 1.790 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2

neurexin II

chr10_-_81482655 1.720 ENSMUST00000120508.1
ENSMUST00000118763.1
Celf5

CUGBP, Elav-like family member 5

chr3_+_26331150 1.649 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr17_+_46297917 1.592 ENSMUST00000166617.1
ENSMUST00000170271.1
Dlk2

delta-like 2 homolog (Drosophila)

chr5_-_136883115 1.278 ENSMUST00000057497.6
ENSMUST00000111103.1
Col26a1

collagen, type XXVI, alpha 1

chr10_+_38965515 1.253 ENSMUST00000019992.5
Lama4
laminin, alpha 4
chr5_-_34187670 1.243 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr11_-_120047144 1.210 ENSMUST00000103020.1
Aatk
apoptosis-associated tyrosine kinase
chr11_+_98741805 1.166 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr11_+_70018421 1.131 ENSMUST00000108588.1
Dlg4
discs, large homolog 4 (Drosophila)
chr15_-_43869993 1.119 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr11_+_98741871 1.072 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr7_-_99695809 1.064 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.6 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 4.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 2.9 GO:0071625 vocalization behavior(GO:0071625)
0.5 2.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 2.6 GO:0098792 xenophagy(GO:0098792)
0.7 2.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 2.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.8 GO:0043589 skin morphogenesis(GO:0043589)
0.0 1.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.1 GO:0035690 cellular response to drug(GO:0035690)
0.2 1.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 1.0 GO:0046684 response to pyrethroid(GO:0046684)
0.0 1.0 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.3 0.9 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.2 0.9 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.9 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.9 GO:0032402 melanosome transport(GO:0032402)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.2 2.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 1.8 GO:0005584 collagen type I trimer(GO:0005584)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.3 GO:0005605 basal lamina(GO:0005605)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.0 GO:0008091 spectrin(GO:0008091)
0.1 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.9 GO:0005869 dynactin complex(GO:0005869)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.6 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.7 2.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 2.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 1.1 GO:0016151 nickel cation binding(GO:0016151)
0.3 1.0 GO:0070905 serine binding(GO:0070905)
0.1 1.0 GO:0031402 sodium ion binding(GO:0031402)
0.3 0.9 GO:0016015 morphogen activity(GO:0016015)
0.2 0.9 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.9 GO:0045502 dynein binding(GO:0045502)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)