Motif ID: Pou2f2_Pou3f1

Z-value: 1.600

Transcription factors associated with Pou2f2_Pou3f1:

Gene SymbolEntrez IDGene Name
Pou2f2 ENSMUSG00000008496.12 Pou2f2
Pou3f1 ENSMUSG00000090125.2 Pou3f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f1mm10_v2_chr4_+_124657646_1246576560.395.0e-02Click!
Pou2f2mm10_v2_chr7_-_25132473_251325120.301.4e-01Click!


Activity profile for motif Pou2f2_Pou3f1.

activity profile for motif Pou2f2_Pou3f1


Sorted Z-values histogram for motif Pou2f2_Pou3f1

Sorted Z-values for motif Pou2f2_Pou3f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_24507099 23.045 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr13_-_22042949 9.230 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr13_+_23751069 9.148 ENSMUST00000078369.1
 Hist1h2ab
histone cluster 1, H2ab
chr13_-_21833575 9.095 ENSMUST00000081342.5
 Hist1h2ap
histone cluster 1, H2ap
chr3_-_96240317 8.212 ENSMUST00000078756.5
 Hist2h2aa2
histone cluster 2, H2aa2
chr13_-_23571151 8.143 ENSMUST00000102969.3
 Hist1h2ae
histone cluster 1, H2ae
chr13_+_23574381 7.954 ENSMUST00000090776.4
 Hist1h2ad
histone cluster 1, H2ad
chr13_-_22035589 7.904 ENSMUST00000091742.4
 Hist1h2ah
histone cluster 1, H2ah
chr7_+_24507006 6.689 ENSMUST00000176880.1
 Zfp428
zinc finger protein 428
chr3_+_96245530 6.043 ENSMUST00000074976.6
 Hist2h2aa1
histone cluster 2, H2aa1
chr13_-_23683941 5.938 ENSMUST00000171127.1
 Hist1h2ac
histone cluster 1, H2ac
chr3_-_96220880 4.972 ENSMUST00000090782.3
 Hist2h2ac
histone cluster 2, H2ac
chr13_+_23533869 4.861 ENSMUST00000073261.2
 Hist1h2af
histone cluster 1, H2af
chr13_-_21787218 4.633 ENSMUST00000091751.2
 Hist1h2an
histone cluster 1, H2an
chr11_+_58948890 4.544 ENSMUST00000078267.3
 Hist3h2ba
histone cluster 3, H2ba
chr2_-_30474199 4.505 ENSMUST00000065134.2
 Ier5l
immediate early response 5-like
chr13_+_21810428 4.488 ENSMUST00000091745.5
 Hist1h2ao
histone cluster 1, H2ao
chr7_+_24507122 4.479 ENSMUST00000177205.1
 Zfp428
zinc finger protein 428
chr11_+_58954675 4.297 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr13_-_23934156 4.260 ENSMUST00000052776.2
 Hist1h2ba
histone cluster 1, H2ba

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 87.3 GO:0006342 chromatin silencing(GO:0006342)
0.1 13.3 GO:0006334 nucleosome assembly(GO:0006334)
0.7 7.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.9 4.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.4 4.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 4.1 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.9 3.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 3.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 3.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 3.5 GO:0098656 anion transmembrane transport(GO:0098656)
0.6 3.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.5 2.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4 2.6 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.4 2.6 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2 2.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 2.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.7 2.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.3 2.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 2.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.3 1.9 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) neural crest cell migration involved in autonomic nervous system development(GO:1901166)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 60.1 GO:0000790 nuclear chromatin(GO:0000790)
0.8 27.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 22.5 GO:0000786 nucleosome(GO:0000786)
0.1 4.3 GO:0005776 autophagosome(GO:0005776)
0.0 3.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 2.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.6 GO:0031965 nuclear membrane(GO:0031965)
0.6 2.2 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 2.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.3 1.1 GO:0061702 inflammasome complex(GO:0061702)
0.1 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 42.9 GO:0003677 DNA binding(GO:0003677)
0.0 37.0 GO:0046872 metal ion binding(GO:0046872)
0.1 32.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 4.5 GO:0043130 ubiquitin binding(GO:0043130)
0.1 4.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 3.6 GO:0042393 histone binding(GO:0042393)
0.3 3.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.9 3.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 3.4 GO:0070888 E-box binding(GO:0070888)
0.1 2.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 2.6 GO:0005262 calcium channel activity(GO:0005262)
0.7 2.1 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 2.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 1.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.4 GO:0005057 receptor signaling protein activity(GO:0005057)
0.3 1.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.2 GO:0070644 vitamin D response element binding(GO:0070644)