Motif ID: Pou3f4

Z-value: 0.757


Transcription factors associated with Pou3f4:

Gene SymbolEntrez IDGene Name
Pou3f4 ENSMUSG00000056854.3 Pou3f4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f4mm10_v2_chrX_+_110814390_1108144130.432.9e-02Click!


Activity profile for motif Pou3f4.

activity profile for motif Pou3f4


Sorted Z-values histogram for motif Pou3f4

Sorted Z-values for motif Pou3f4



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f4

PNG image of the network

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Top targets:


Showing 1 to 20 of 134 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_55742242 3.839 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
 Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr19_+_55741810 3.670 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr19_+_55741884 3.400 ENSMUST00000111658.3
ENSMUST00000111654.1
 Tcf7l2

transcription factor 7 like 2, T cell specific, HMG box

chr19_+_55742056 3.296 ENSMUST00000111659.2
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr7_+_113765998 2.600 ENSMUST00000046687.9
 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr5_+_147188678 2.510 ENSMUST00000065382.5
 Gsx1
GS homeobox 1
chr5_+_28165690 2.328 ENSMUST00000036177.7
 En2
engrailed 2
chr14_-_104467984 2.322 ENSMUST00000053016.8
 Pou4f1
POU domain, class 4, transcription factor 1
chr1_-_89933290 2.198 ENSMUST00000036954.7
 Gbx2
gastrulation brain homeobox 2
chr6_+_34354119 2.167 ENSMUST00000038406.6
 Akr1b8
aldo-keto reductase family 1, member B8
chr4_+_15881255 1.910 ENSMUST00000029876.1
 Calb1
calbindin 1
chr14_-_96519067 1.636 ENSMUST00000022666.7
 Klhl1
kelch-like 1
chr11_-_11890368 1.631 ENSMUST00000155690.1
 Ddc
dopa decarboxylase
chr11_-_11890394 1.618 ENSMUST00000109659.2
 Ddc
dopa decarboxylase
chr15_-_100599864 1.180 ENSMUST00000177247.2
ENSMUST00000177505.2
 Pou6f1

POU domain, class 6, transcription factor 1

chr8_+_62951195 0.962 ENSMUST00000118003.1
 Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr8_+_62951361 0.891 ENSMUST00000119068.1
 Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr19_-_58455903 0.866 ENSMUST00000131877.1
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_-_38898084 0.838 ENSMUST00000027249.6
 Chst10
carbohydrate sulfotransferase 10
chr8_+_12984246 0.794 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
 Mcf2l


mcf.2 transforming sequence-like



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 14.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.5 3.2 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 2.5 GO:0021984 adenohypophysis development(GO:0021984)
0.5 2.3 GO:0019230 proprioception(GO:0019230)
0.2 2.3 GO:1990403 embryonic brain development(GO:1990403)
0.7 2.2 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.3 2.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2 1.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.9 GO:0007614 short-term memory(GO:0007614)
0.1 1.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 1.1 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.1 0.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:0060065 uterus development(GO:0060065)
0.0 0.8 GO:0007616 long-term memory(GO:0007616)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.2 0.5 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.2 0.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 14.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 4.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.9 GO:0043195 terminal bouton(GO:0043195)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0030867 desmosome(GO:0030057) rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.2 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 14.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.8 3.2 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.0 2.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 2.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.4 2.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.9 GO:0019842 vitamin binding(GO:0019842)
0.0 1.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.3 1.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0016918 retinal binding(GO:0016918)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)