Motif ID: Pou4f1_Pou6f1

Z-value: 0.635

Transcription factors associated with Pou4f1_Pou6f1:

Gene SymbolEntrez IDGene Name
Pou4f1 ENSMUSG00000048349.8 Pou4f1
Pou6f1 ENSMUSG00000009739.10 Pou6f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f1mm10_v2_chr15_-_100599983_1006000390.601.2e-03Click!
Pou4f1mm10_v2_chr14_-_104467984_104468041-0.232.7e-01Click!


Activity profile for motif Pou4f1_Pou6f1.

activity profile for motif Pou4f1_Pou6f1


Sorted Z-values histogram for motif Pou4f1_Pou6f1

Sorted Z-values for motif Pou4f1_Pou6f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f1_Pou6f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_92161343 2.004 ENSMUST00000068378.5
 Cntn1
contactin 1
chr13_+_42681513 1.940 ENSMUST00000149235.1
 Phactr1
phosphatase and actin regulator 1
chr17_-_50094277 1.596 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr9_-_58202281 1.461 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_-_56978534 1.347 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr14_-_30353468 1.328 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr9_-_58201705 1.254 ENSMUST00000163200.1
ENSMUST00000165276.1
 Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr18_+_37504264 1.254 ENSMUST00000052179.6
 Pcdhb20
protocadherin beta 20
chr15_-_100599983 1.180 ENSMUST00000073837.6
 Pou6f1
POU domain, class 6, transcription factor 1
chr15_-_100599864 1.150 ENSMUST00000177247.2
ENSMUST00000177505.2
 Pou6f1

POU domain, class 6, transcription factor 1

chr10_-_64090241 1.139 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr11_+_98348404 1.054 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr4_+_152338619 1.005 ENSMUST00000030775.5
ENSMUST00000164662.1
 Chd5

chromodomain helicase DNA binding protein 5

chr16_+_91269759 0.995 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr9_+_113812547 0.929 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
 Clasp2


CLIP associating protein 2


chr4_+_102254993 0.879 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr8_+_12984246 0.841 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
 Mcf2l


mcf.2 transforming sequence-like


chr15_+_18818895 0.833 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr13_+_83504032 0.791 ENSMUST00000163888.1
ENSMUST00000005722.7
 Mef2c

myocyte enhancer factor 2C

chr9_-_103222063 0.786 ENSMUST00000170904.1
 Trf
transferrin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 2.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 2.0 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 1.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.3 1.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.6 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 1.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.4 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.4 1.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.3 GO:0007097 nuclear migration(GO:0007097)
0.4 1.2 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.2 1.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.4 1.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 1.1 GO:0009414 response to water deprivation(GO:0009414)
0.2 1.0 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.2 0.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 0.8 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
0.1 0.8 GO:0097460 ferrous iron import into cell(GO:0097460)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 0.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:0033263 CORVET complex(GO:0033263)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0 2.0 GO:0001948 glycoprotein binding(GO:0001948)
0.1 1.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 1.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 1.1 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)