Motif ID: Pou4f1_Pou6f1
Z-value: 0.635
Transcription factors associated with Pou4f1_Pou6f1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou4f1 | ENSMUSG00000048349.8 | Pou4f1 |
Pou6f1 | ENSMUSG00000009739.10 | Pou6f1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou6f1 | mm10_v2_chr15_-_100599983_100600039 | 0.60 | 1.2e-03 | Click! |
Pou4f1 | mm10_v2_chr14_-_104467984_104468041 | -0.23 | 2.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.4 | 1.2 | GO:1904685 | positive regulation of metalloendopeptidase activity(GO:1904685) |
0.4 | 1.1 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.3 | 1.6 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.3 | 1.1 | GO:0009414 | response to water deprivation(GO:0009414) |
0.3 | 0.8 | GO:0007521 | muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
0.2 | 1.2 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.2 | 1.0 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.2 | 2.5 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.2 | 0.4 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.2 | 0.5 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
0.2 | 0.9 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.2 | 0.5 | GO:1904395 | regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.1 | 0.4 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
0.1 | 0.6 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.1 | 0.5 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.1 | 1.4 | GO:1901629 | regulation of presynaptic membrane organization(GO:1901629) |
0.1 | 0.8 | GO:0097460 | ferrous iron import into cell(GO:0097460) |
0.1 | 1.6 | GO:1902993 | positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993) |
0.1 | 1.6 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.1 | 0.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.1 | 0.5 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
0.1 | 1.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.1 | 0.4 | GO:0021856 | cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375) |
0.1 | 0.5 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.1 | 0.4 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
0.1 | 0.3 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
0.1 | 0.2 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.1 | 0.2 | GO:0045404 | positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
0.1 | 0.3 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
0.1 | 0.3 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.1 | 0.2 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.1 | 0.2 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.1 | 0.2 | GO:0006780 | uroporphyrinogen III biosynthetic process(GO:0006780) |
0.1 | 0.8 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.1 | 1.3 | GO:0007097 | nuclear migration(GO:0007097) |
0.1 | 0.4 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 0.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.1 | 0.5 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.0 | 2.7 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.0 | 0.4 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.0 | 0.3 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.0 | 0.1 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.0 | 0.4 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.0 | 0.1 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.0 | 0.8 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.0 | 0.1 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
0.0 | 0.3 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.0 | 0.6 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.0 | 0.1 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.0 | 0.1 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.0 | 0.2 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.0 | 2.0 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
0.0 | 0.2 | GO:0043206 | extracellular fibril organization(GO:0043206) |
0.0 | 0.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.4 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
0.0 | 1.0 | GO:0019228 | neuronal action potential(GO:0019228) |
0.0 | 0.1 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.0 | 0.2 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
0.0 | 0.1 | GO:1900110 | negative regulation of histone H3-K9 dimethylation(GO:1900110) |
0.0 | 0.3 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.0 | 0.3 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 1.9 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
0.0 | 0.4 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 0.7 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.0 | 0.1 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
0.0 | 0.0 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) |
0.0 | 0.2 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.0 | 0.2 | GO:0032402 | melanosome transport(GO:0032402) |
0.0 | 0.0 | GO:0071726 | response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
0.0 | 0.8 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.1 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
0.0 | 0.3 | GO:0031103 | axon regeneration(GO:0031103) |
0.0 | 0.1 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 0.4 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.9 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 0.4 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.1 | 1.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.1 | 0.8 | GO:0097433 | dense body(GO:0097433) |
0.1 | 2.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 0.5 | GO:0033263 | CORVET complex(GO:0033263) |
0.1 | 0.3 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.1 | 1.0 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.0 | 0.4 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.2 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.0 | 1.0 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.1 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 1.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.5 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 0.1 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
0.0 | 0.4 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.0 | 0.1 | GO:0005955 | calcineurin complex(GO:0005955) |
0.0 | 0.1 | GO:0097361 | CIA complex(GO:0097361) |
0.0 | 0.4 | GO:0031672 | A band(GO:0031672) |
0.0 | 2.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.1 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
0.0 | 1.3 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.5 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 3.8 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.1 | GO:0097255 | R2TP complex(GO:0097255) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.1 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
0.2 | 1.3 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
0.2 | 0.6 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.2 | 0.6 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.2 | 0.5 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
0.1 | 0.4 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.1 | 1.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.1 | 0.5 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.1 | 0.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.1 | 1.9 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.1 | 0.8 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 0.3 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.1 | 0.6 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.1 | 0.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 0.6 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.1 | 0.3 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.1 | 0.3 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.1 | 0.8 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 0.4 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.1 | 0.2 | GO:0004556 | alpha-amylase activity(GO:0004556) |
0.1 | 0.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.1 | 0.4 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.1 | 0.9 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.1 | 1.4 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 0.4 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.1 | 1.0 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 2.6 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.1 | 0.3 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.0 | 0.2 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
0.0 | 0.8 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.4 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.2 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.0 | 0.4 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.2 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
0.0 | 0.1 | GO:0004008 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
0.0 | 0.1 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
0.0 | 0.2 | GO:0008808 | cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) |
0.0 | 0.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.5 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.0 | 0.4 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.0 | 0.1 | GO:0015183 | sulfur amino acid transmembrane transporter activity(GO:0000099) L-aspartate transmembrane transporter activity(GO:0015183) |
0.0 | 0.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.4 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 0.1 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.0 | 0.1 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.0 | 1.6 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.0 | 0.3 | GO:0016594 | glycine binding(GO:0016594) |
0.0 | 2.0 | GO:0001948 | glycoprotein binding(GO:0001948) |
0.0 | 0.4 | GO:0031402 | sodium ion binding(GO:0031402) |
0.0 | 0.2 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.0 | 0.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.0 | 0.0 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.0 | 0.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
0.0 | 1.0 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 0.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 1.4 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 0.1 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |