Motif ID: Pou5f1

Z-value: 2.306


Transcription factors associated with Pou5f1:

Gene SymbolEntrez IDGene Name
Pou5f1 ENSMUSG00000024406.10 Pou5f1



Activity profile for motif Pou5f1.

activity profile for motif Pou5f1


Sorted Z-values histogram for motif Pou5f1

Sorted Z-values for motif Pou5f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou5f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 28.430 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr7_+_24507099 21.574 ENSMUST00000177228.1
 Zfp428
zinc finger protein 428
chr8_+_54954728 18.057 ENSMUST00000033915.7
 Gpm6a
glycoprotein m6a
chr15_-_66831625 18.052 ENSMUST00000164163.1
 Sla
src-like adaptor
chr4_-_64046925 16.131 ENSMUST00000107377.3
 Tnc
tenascin C
chr3_-_50443603 14.938 ENSMUST00000029297.4
 Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr6_-_55681257 14.244 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr11_+_98741805 11.970 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr7_+_91090697 11.009 ENSMUST00000107196.2
 Dlg2
discs, large homolog 2 (Drosophila)
chr8_+_118283719 10.853 ENSMUST00000117160.1
 Cdh13
cadherin 13
chr8_-_115707778 10.785 ENSMUST00000109104.1
 Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr7_+_91090728 10.699 ENSMUST00000074273.3
 Dlg2
discs, large homolog 2 (Drosophila)
chr3_-_80802789 10.352 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr11_+_57011945 10.325 ENSMUST00000094179.4
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_57011798 10.313 ENSMUST00000036315.9
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_98741871 10.311 ENSMUST00000103139.4
 Thra
thyroid hormone receptor alpha
chr12_+_29528382 10.131 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr2_+_124610573 9.989 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr7_+_87803815 9.814 ENSMUST00000125009.1
ENSMUST00000155358.1
 Grm5

glutamate receptor, metabotropic 5

chr14_-_79771305 9.681 ENSMUST00000039568.5
 Pcdh8
protocadherin 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 35.0 GO:0006342 chromatin silencing(GO:0006342)
0.2 30.7 GO:0031032 actomyosin structure organization(GO:0031032)
1.9 25.9 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
7.4 22.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.6 21.8 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
1.6 21.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
2.2 21.6 GO:0042118 endothelial cell activation(GO:0042118)
0.7 20.6 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.3 19.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
2.6 18.1 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.8 16.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.1 16.2 GO:0021542 dentate gyrus development(GO:0021542)
4.0 16.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.6 15.5 GO:0060074 synapse maturation(GO:0060074)
2.5 14.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.6 14.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
2.5 12.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.0 11.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 11.7 GO:0006897 endocytosis(GO:0006897)
2.7 10.9 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 34.1 GO:0005768 endosome(GO:0005768)
0.7 22.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 22.2 GO:0005739 mitochondrion(GO:0005739)
1.1 22.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
3.4 20.6 GO:0044308 axonal spine(GO:0044308)
0.4 20.5 GO:0044295 axonal growth cone(GO:0044295)
1.0 18.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 17.4 GO:0045211 postsynaptic membrane(GO:0045211)
1.0 16.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 16.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 16.0 GO:0031225 anchored component of membrane(GO:0031225)
0.2 14.4 GO:0042734 presynaptic membrane(GO:0042734)
0.7 12.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 10.2 GO:0015629 actin cytoskeleton(GO:0015629)
0.8 9.8 GO:0097449 astrocyte projection(GO:0097449)
0.2 9.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 9.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 8.2 GO:0000786 nucleosome(GO:0000786)
0.2 8.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.1 7.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.4 31.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
7.4 22.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.0 21.7 GO:0004385 guanylate kinase activity(GO:0004385)
5.4 21.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 21.5 GO:0005262 calcium channel activity(GO:0005262)
0.1 20.7 GO:0003779 actin binding(GO:0003779)
1.3 18.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.4 16.2 GO:0045499 chemorepellent activity(GO:0045499)
2.7 16.1 GO:0045545 syndecan binding(GO:0045545)
3.7 14.9 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
3.1 12.3 GO:0097109 neuroligin family protein binding(GO:0097109)
2.2 10.9 GO:0055100 adiponectin binding(GO:0055100)
1.4 9.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
3.3 9.8 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.2 9.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 9.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 8.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 8.1 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 7.9 GO:0008289 lipid binding(GO:0008289)
0.8 7.8 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)