Motif ID: Pou6f2_Pou4f2

Z-value: 0.495

Transcription factors associated with Pou6f2_Pou4f2:

Gene SymbolEntrez IDGene Name
Pou4f2 ENSMUSG00000031688.3 Pou4f2
Pou6f2 ENSMUSG00000009734.11 Pou6f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f2mm10_v2_chr8_-_78436640_784366490.618.5e-04Click!
Pou6f2mm10_v2_chr13_-_18382041_183820410.481.2e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 2.151 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr2_+_109917639 1.970 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr7_-_49636847 1.898 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr1_+_153665666 1.428 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr4_+_115088708 1.349 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
Pdzk1ip1



PDZK1 interacting protein 1



chr1_+_153665274 1.336 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr1_+_153665587 1.279 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr12_-_56535047 1.183 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr3_+_55782500 1.155 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr1_+_153665627 1.142 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr8_-_92355764 1.106 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr13_-_81570640 1.026 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr13_-_56296551 0.865 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr2_-_148046896 0.771 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr18_-_31949571 0.636 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr3_-_154328634 0.629 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr6_+_63255971 0.581 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr7_-_70366735 0.579 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr2_-_148045891 0.544 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr2_-_168767029 0.525 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 2.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.7 2.0 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 2.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 1.3 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.4 1.2 GO:0021759 globus pallidus development(GO:0021759)
0.3 0.9 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.6 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 0.3 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.4 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0044302 dentate gyrus mossy fiber(GO:0044302)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.1 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.6 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)