Motif ID: Pparg_Rxrg

Z-value: 1.201

Transcription factors associated with Pparg_Rxrg:

Gene SymbolEntrez IDGene Name
Pparg ENSMUSG00000000440.6 Pparg
Rxrg ENSMUSG00000015843.4 Rxrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgmm10_v2_chr1_+_167598384_167598411-0.116.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pparg_Rxrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 5.959 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr7_+_4925802 5.518 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr12_+_109452833 5.356 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr11_-_77894096 5.075 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr13_-_24761861 4.483 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr7_-_103843154 4.352 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr2_+_126556128 4.314 ENSMUST00000141482.2
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr19_-_43912392 3.758 ENSMUST00000026209.4
Dnmbp
dynamin binding protein
chr5_+_110286306 3.565 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr9_+_64117147 3.536 ENSMUST00000034969.7
Lctl
lactase-like
chr11_-_100354040 3.409 ENSMUST00000173630.1
Hap1
huntingtin-associated protein 1
chr4_+_126556935 3.098 ENSMUST00000048391.8
Clspn
claspin
chr19_+_59260878 3.050 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chrX_-_106485214 2.930 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr4_+_126556994 2.804 ENSMUST00000147675.1
Clspn
claspin
chr11_-_100759942 2.740 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr6_+_34354119 2.724 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr18_-_41951187 2.612 ENSMUST00000070949.4
Prelid2
PRELI domain containing 2
chr17_+_35049966 2.493 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr17_-_23844155 2.462 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
Prss41


protease, serine, 41



Gene overrepresentation in biological_process category:

Showing 1 to 20 of 350 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.0 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.7 5.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 5.9 GO:0001522 pseudouridine synthesis(GO:0001522)
1.1 5.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.3 5.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 5.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 5.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.9 5.3 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
1.7 5.1 GO:0006553 lysine metabolic process(GO:0006553)
0.7 4.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.9 4.4 GO:0015671 oxygen transport(GO:0015671)
1.4 4.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 4.0 GO:0006000 fructose metabolic process(GO:0006000)
0.1 3.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 3.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.6 3.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.5 3.6 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.9 3.4 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.1 3.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 3.0 GO:0060021 palate development(GO:0060021)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 136 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 7.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 6.6 GO:0005730 nucleolus(GO:0005730)
0.0 5.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.3 GO:0005903 brush border(GO:0005903)
0.5 4.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 4.2 GO:0005814 centriole(GO:0005814)
0.3 4.0 GO:0031045 dense core granule(GO:0031045)
0.5 3.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7 3.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 3.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 3.5 GO:0031968 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 3.5 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.7 3.4 GO:0097149 centralspindlin complex(GO:0097149)
0.2 3.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 3.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.3 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 2.9 GO:0000145 exocyst(GO:0000145)
0.0 2.9 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 249 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.7 6.4 GO:0001972 retinoic acid binding(GO:0001972)
1.0 5.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.5 5.9 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.1 5.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 5.6 GO:0043236 laminin binding(GO:0043236)
1.3 5.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.4 5.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 4.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.1 4.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 4.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 4.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.3 4.0 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.1 3.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.4 3.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 3.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 3.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.0 3.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)