Motif ID: Prop1

Z-value: 0.944


Transcription factors associated with Prop1:

Gene SymbolEntrez IDGene Name
Prop1 ENSMUSG00000044542.3 Prop1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prop1mm10_v2_chr11_-_50953745_509537680.262.0e-01Click!


Activity profile for motif Prop1.

activity profile for motif Prop1


Sorted Z-values histogram for motif Prop1

Sorted Z-values for motif Prop1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prop1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_45470201 3.202 ENSMUST00000079390.6
 Lin28b
lin-28 homolog B (C. elegans)
chr3_+_94377432 2.936 ENSMUST00000107292.1
 Rorc
RAR-related orphan receptor gamma
chr3_+_94377505 2.698 ENSMUST00000098877.2
 Rorc
RAR-related orphan receptor gamma
chr18_-_13972617 2.618 ENSMUST00000025288.7
 Zfp521
zinc finger protein 521
chr19_+_38395980 2.445 ENSMUST00000054098.2
 Slc35g1
solute carrier family 35, member G1
chr13_+_24327415 2.174 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr12_+_79297345 2.122 ENSMUST00000079533.5
ENSMUST00000171210.1
 Rad51b

RAD51 homolog B

chr4_-_3938354 2.042 ENSMUST00000003369.3
 Plag1
pleiomorphic adenoma gene 1
chr14_-_40893222 2.036 ENSMUST00000096000.3
 Sh2d4b
SH2 domain containing 4B
chr14_+_73237891 1.854 ENSMUST00000044405.6
 Lpar6
lysophosphatidic acid receptor 6
chr12_-_55014329 1.847 ENSMUST00000172875.1
 Baz1a
bromodomain adjacent to zinc finger domain 1A
chr4_-_110292719 1.828 ENSMUST00000106601.1
 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_+_27556613 1.791 ENSMUST00000117600.1
ENSMUST00000114888.3
 Hmga1

high mobility group AT-hook 1

chr2_+_20737306 1.726 ENSMUST00000114606.1
ENSMUST00000114608.1
 Etl4

enhancer trap locus 4

chr14_+_75455957 1.712 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr3_+_146121655 1.709 ENSMUST00000039450.4
 Mcoln3
mucolipin 3
chr17_+_27556668 1.698 ENSMUST00000117254.1
ENSMUST00000118570.1
 Hmga1

high mobility group AT-hook 1

chr3_-_141982224 1.589 ENSMUST00000029948.8
 Bmpr1b
bone morphogenetic protein receptor, type 1B
chr17_+_27556641 1.582 ENSMUST00000119486.1
ENSMUST00000118599.1
 Hmga1

high mobility group AT-hook 1

chr9_+_35423582 1.572 ENSMUST00000154652.1
 Cdon
cell adhesion molecule-related/down-regulated by oncogenes

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 5.6 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.1 5.1 GO:0006284 base-excision repair(GO:0006284)
0.4 3.2 GO:0010587 miRNA catabolic process(GO:0010587)
1.0 2.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.8 2.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.7 2.2 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.5 2.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 2.0 GO:0060736 prostate gland growth(GO:0060736)
0.0 1.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.4 1.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.7 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 1.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 1.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.4 1.6 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 1.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 1.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.5 1.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.4 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 1.4 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.4 1.3 GO:0006285 base-excision repair, AP site formation(GO:0006285)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 5.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 2.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.4 1.8 GO:0008623 CHRAC(GO:0008623)
0.1 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 1.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.7 GO:0070469 respiratory chain(GO:0070469)
0.5 1.4 GO:1990423 RZZ complex(GO:1990423)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 1.1 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.1 GO:0071439 clathrin complex(GO:0071439)
0.2 1.0 GO:0045179 apical cortex(GO:0045179)
0.1 0.9 GO:0033269 internode region of axon(GO:0033269)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.7 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.2 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 5.6 GO:0008142 oxysterol binding(GO:0008142)
0.6 5.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 3.9 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.1 3.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 2.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.7 2.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 2.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 2.1 GO:0000150 recombinase activity(GO:0000150)
0.1 1.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.7 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.3 1.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 1.3 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 1.1 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)