Motif ID: Prox1
Z-value: 0.556
Transcription factors associated with Prox1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Prox1 | ENSMUSG00000010175.7 | Prox1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Prox1 | mm10_v2_chr1_-_190169399_190169526 | -0.45 | 2.1e-02 | Click! |
Top targets:
Showing 1 to 20 of 68 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 26 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.0 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) |
| 0.0 | 1.9 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.1 | 1.3 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
| 0.0 | 1.2 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 1.2 | GO:0009408 | response to heat(GO:0009408) |
| 0.0 | 1.1 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.3 | 1.0 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) phenotypic switching(GO:0036166) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
| 0.0 | 1.0 | GO:0009409 | response to cold(GO:0009409) |
| 0.1 | 0.7 | GO:0042711 | maternal behavior(GO:0042711) |
| 0.0 | 0.7 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.5 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.5 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.1 | 0.4 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 0.0 | 0.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.3 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 0.0 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.3 | GO:0002082 | regulation of oxidative phosphorylation(GO:0002082) |
| 0.1 | 0.2 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.1 | 0.2 | GO:0070973 | COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.1 | 0.2 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
Gene overrepresentation in cellular_component category:
Showing 1 to 11 of 11 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.7 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.1 | 1.3 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 1.2 | GO:0016234 | inclusion body(GO:0016234) |
| 0.1 | 1.0 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 1.0 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.0 | 0.4 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.3 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.3 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.3 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 0.2 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.0 | 0.1 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
Gene overrepresentation in molecular_function category:
Showing 1 to 14 of 14 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.3 | 1.7 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.2 | 1.2 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.1 | 1.1 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.2 | 1.0 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.9 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.2 | 0.5 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.0 | 0.5 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.4 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.0 | 0.3 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.0 | 0.3 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.3 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.2 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.0 | 0.1 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
