Motif ID: Prrx1_Isx_Prrxl1

Z-value: 0.693

Transcription factors associated with Prrx1_Isx_Prrxl1:

Gene SymbolEntrez IDGene Name
Isx ENSMUSG00000031621.3 Isx
Prrx1 ENSMUSG00000026586.10 Prrx1
Prrxl1 ENSMUSG00000041730.7 Prrxl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prrxl1mm10_v2_chr14_+_32599922_32599932-0.767.0e-06Click!
Prrx1mm10_v2_chr1_-_163289214_1632892350.144.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Prrx1_Isx_Prrxl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_118478344 2.977 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478182 2.833 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr7_-_79386943 2.731 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr18_-_66860458 2.104 ENSMUST00000057942.2
Mc4r
melanocortin 4 receptor
chr2_+_61804453 1.829 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr9_+_35423582 1.739 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr4_+_5724304 1.345 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr2_-_67194695 1.277 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr17_+_3397189 1.271 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr14_+_80000292 1.228 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr18_+_69593361 1.223 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr4_-_87806296 1.133 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr18_-_78206408 1.128 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr14_-_101609033 1.074 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chr11_+_94936224 0.974 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr2_+_158666690 0.974 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr1_-_158356258 0.936 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr5_-_124095749 0.913 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr1_-_56969864 0.906 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr14_-_118052235 0.891 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr1_-_152625212 0.850 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr4_-_82505749 0.800 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr4_-_87806276 0.781 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_56969827 0.780 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr15_-_8710734 0.772 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_82505707 0.768 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr2_+_116067213 0.734 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr15_-_8710409 0.728 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_116067391 0.707 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr4_-_82505274 0.695 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr1_+_58210397 0.692 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr8_+_94172618 0.643 ENSMUST00000034214.6
Mt2
metallothionein 2
chr4_-_58499398 0.616 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr3_-_59220150 0.605 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr5_-_62766153 0.590 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_48911067 0.557 ENSMUST00000003826.7
Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr8_-_8660773 0.515 ENSMUST00000001319.7
Efnb2
ephrin B2
chr4_-_14621805 0.511 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr4_+_102589687 0.506 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr3_+_86070915 0.499 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr18_+_37320374 0.484 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr2_-_33942111 0.480 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr2_+_20737306 0.471 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr2_-_160619971 0.456 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr12_-_25096080 0.440 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr13_-_105271039 0.411 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr15_+_21111452 0.409 ENSMUST00000075132.6
Cdh12
cadherin 12
chr15_+_98571004 0.395 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr8_-_105966038 0.376 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr10_+_99263224 0.354 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr2_-_45110336 0.353 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr3_+_84593547 0.350 ENSMUST00000062623.3
Tigd4
tigger transposable element derived 4
chr17_+_56613392 0.346 ENSMUST00000080492.5
Rpl36
ribosomal protein L36
chrM_+_10167 0.344 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr18_-_39487096 0.343 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr8_+_121116163 0.330 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr5_+_130369420 0.323 ENSMUST00000086029.3
Caln1
calneuron 1
chr2_+_91257323 0.322 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr4_-_14621494 0.318 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr2_-_170194033 0.317 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr5_-_84417359 0.310 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr11_-_117873433 0.303 ENSMUST00000033230.7
Tha1
threonine aldolase 1
chr10_-_127189981 0.303 ENSMUST00000019611.7
Arhgef25
Rho guanine nucleotide exchange factor (GEF) 25
chr3_+_89715016 0.303 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chr17_-_45599603 0.299 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr6_-_37442095 0.298 ENSMUST00000041093.5
Creb3l2
cAMP responsive element binding protein 3-like 2
chr6_+_58831748 0.298 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr8_+_23411490 0.288 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr3_-_79145875 0.288 ENSMUST00000118340.1
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr9_+_119341294 0.283 ENSMUST00000039784.5
Acaa1a
acetyl-Coenzyme A acyltransferase 1A
chr10_+_127420867 0.281 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chrX_+_159708593 0.281 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr9_-_42399915 0.275 ENSMUST00000042190.7
Tecta
tectorin alpha
chr16_-_17144415 0.275 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr5_+_15516489 0.274 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr15_+_81744848 0.269 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr11_+_90030295 0.268 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr9_+_80165079 0.262 ENSMUST00000184480.1
Myo6
myosin VI
chr9_-_71163224 0.259 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr8_+_54954728 0.256 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chrX_-_59166080 0.253 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr7_-_110844350 0.253 ENSMUST00000177462.1
ENSMUST00000176746.1
ENSMUST00000177236.1
Rnf141


ring finger protein 141


chr7_-_45526146 0.250 ENSMUST00000167273.1
ENSMUST00000042105.8
Ppp1r15a

protein phosphatase 1, regulatory (inhibitor) subunit 15A

chr7_-_79848191 0.250 ENSMUST00000107392.1
Anpep
alanyl (membrane) aminopeptidase
chr12_-_4841583 0.246 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr10_+_127421124 0.245 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr7_-_127895578 0.243 ENSMUST00000033074.6
Vkorc1
vitamin K epoxide reductase complex, subunit 1
chr14_-_76010863 0.241 ENSMUST00000088922.4
Gtf2f2
general transcription factor IIF, polypeptide 2
chr4_+_59035088 0.241 ENSMUST00000041160.6
Gng10
guanine nucleotide binding protein (G protein), gamma 10
chr9_+_119341487 0.240 ENSMUST00000175743.1
ENSMUST00000176397.1
Acaa1a

acetyl-Coenzyme A acyltransferase 1A

chr6_-_136173492 0.240 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr9_-_42399709 0.239 ENSMUST00000160940.1
Tecta
tectorin alpha
chr3_-_86142684 0.228 ENSMUST00000029722.6
Rps3a1
ribosomal protein S3A1
chr13_+_42681513 0.225 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr5_-_35105691 0.224 ENSMUST00000030986.8
Lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr14_-_7483762 0.222 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr3_-_66296807 0.222 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr4_+_110397661 0.216 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr11_+_32000452 0.215 ENSMUST00000020537.2
ENSMUST00000109409.1
Nsg2

neuron specific gene family member 2

chr4_-_32923455 0.215 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr9_-_77347816 0.214 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr2_-_34913976 0.213 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr16_-_90810365 0.213 ENSMUST00000140920.1
Urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr3_-_141982224 0.211 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr9_+_92457369 0.210 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chr4_-_14621669 0.210 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr7_+_126695355 0.209 ENSMUST00000130498.1
Bola2
bolA-like 2 (E. coli)
chr2_-_34826071 0.205 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr2_-_72986716 0.194 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr17_-_36042690 0.193 ENSMUST00000058801.8
ENSMUST00000080015.5
ENSMUST00000077960.6
H2-T22


histocompatibility 2, T region locus 22


chr5_+_109940426 0.190 ENSMUST00000170826.1
Gm15446
predicted gene 15446
chr18_+_60774675 0.189 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr2_-_84650760 0.188 ENSMUST00000111691.1
Ctnnd1
catenin (cadherin associated protein), delta 1
chr18_+_60774510 0.186 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr5_-_62765618 0.185 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_+_45526330 0.181 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr9_-_77347787 0.181 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr12_-_80643799 0.180 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr3_+_136670076 0.180 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr14_-_18893376 0.179 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr4_+_154964117 0.173 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr10_+_19951055 0.173 ENSMUST00000152533.1
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr6_-_136875794 0.171 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr1_+_180111339 0.169 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr11_-_98729374 0.167 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr11_+_32000496 0.162 ENSMUST00000093219.3
Nsg2
neuron specific gene family member 2
chr10_-_42583628 0.159 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr7_-_44892358 0.158 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr4_+_102430047 0.158 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_-_162898665 0.156 ENSMUST00000111510.1
ENSMUST00000045902.6
Fmo2

flavin containing monooxygenase 2

chr19_-_19001099 0.155 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr10_-_18743691 0.154 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr12_-_84617326 0.149 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr1_-_182282738 0.149 ENSMUST00000035295.5
Degs1
degenerative spermatocyte homolog 1 (Drosophila)
chrX_+_38600626 0.149 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr16_-_36874806 0.149 ENSMUST00000075946.5
Eaf2
ELL associated factor 2
chrX_+_99975570 0.142 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr1_+_170308802 0.141 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr2_-_29787622 0.140 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr1_-_24005608 0.139 ENSMUST00000027338.3
1110058L19Rik
RIKEN cDNA 1110058L19 gene
chr2_-_155945282 0.137 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chr2_+_91256813 0.136 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr8_-_105568298 0.135 ENSMUST00000005849.5
Agrp
agouti related protein
chr16_+_16870736 0.131 ENSMUST00000139740.1
ENSMUST00000119787.2
ENSMUST00000130650.1
ENSMUST00000156502.1
ENSMUST00000023465.7
ENSMUST00000124960.1
ENSMUST00000144513.1
Top3b






topoisomerase (DNA) III beta






chr5_-_151190154 0.131 ENSMUST00000062015.8
ENSMUST00000110483.2
Stard13

StAR-related lipid transfer (START) domain containing 13

chr3_+_88142536 0.130 ENSMUST00000107558.2
ENSMUST00000107559.2
Mef2d

myocyte enhancer factor 2D

chr16_+_38346986 0.129 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr18_+_37435602 0.129 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr18_+_37755718 0.128 ENSMUST00000061279.7
Pcdhga9
protocadherin gamma subfamily A, 9
chrX_+_56963325 0.128 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr18_+_37400845 0.127 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr13_+_93304799 0.124 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chr11_-_113684155 0.123 ENSMUST00000120194.1
Fam104a
family with sequence similarity 104, member A
chr11_-_110095974 0.122 ENSMUST00000100287.2
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr7_-_127376028 0.119 ENSMUST00000067425.4
Zfp747
zinc finger protein 747
chr6_-_86733268 0.119 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr8_-_105484350 0.117 ENSMUST00000044286.5
Zdhhc1
zinc finger, DHHC domain containing 1
chr6_+_17749170 0.115 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr4_-_147868631 0.115 ENSMUST00000030886.8
ENSMUST00000172710.1
Miip

migration and invasion inhibitory protein

chr18_+_75000469 0.114 ENSMUST00000079716.5
Rpl17
ribosomal protein L17
chr1_+_180101144 0.113 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr1_+_88103229 0.113 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr9_-_77347889 0.112 ENSMUST00000185039.1
Mlip
muscular LMNA-interacting protein
chr7_+_140941550 0.111 ENSMUST00000079403.4
Athl1
ATH1, acid trehalase-like 1 (yeast)
chr17_-_36032682 0.111 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr13_+_96388294 0.110 ENSMUST00000099295.4
Poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr10_-_128626464 0.108 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr11_-_84129582 0.107 ENSMUST00000018795.6
Tada2a
transcriptional adaptor 2A
chr2_+_68104671 0.107 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr10_+_127421208 0.107 ENSMUST00000168780.1
R3hdm2
R3H domain containing 2
chr7_+_19368498 0.106 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr9_+_113812547 0.105 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr4_+_109978004 0.104 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr9_-_44802951 0.103 ENSMUST00000044694.6
Ttc36
tetratricopeptide repeat domain 36
chr11_-_17953861 0.103 ENSMUST00000076661.6
Etaa1
Ewing's tumor-associated antigen 1
chr17_-_71460395 0.103 ENSMUST00000180522.1
Gm4707
predicted gene 4707
chr3_-_98339921 0.102 ENSMUST00000065793.5
Phgdh
3-phosphoglycerate dehydrogenase
chr3_+_90476121 0.102 ENSMUST00000001042.8
Ilf2
interleukin enhancer binding factor 2
chr8_-_106573461 0.102 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr7_+_105375053 0.101 ENSMUST00000106805.2
Gm5901
predicted gene 5901
chr5_+_64092925 0.100 ENSMUST00000087324.5
Pgm1
phosphoglucomutase 1
chr14_+_4023941 0.099 ENSMUST00000096184.4
Gm5796
predicted gene 5796
chr2_-_150255591 0.099 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr2_-_174346712 0.098 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr1_-_4785671 0.098 ENSMUST00000130201.1
ENSMUST00000156816.1
Mrpl15

mitochondrial ribosomal protein L15

chrX_+_106015699 0.096 ENSMUST00000033582.4
Cox7b
cytochrome c oxidase subunit VIIb
chr1_+_88134786 0.096 ENSMUST00000113134.1
ENSMUST00000140092.1
Ugt1a6a

UDP glucuronosyltransferase 1 family, polypeptide A6A

chrX_+_163911401 0.096 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr10_-_62342674 0.095 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr17_-_78684262 0.094 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr7_+_19508712 0.093 ENSMUST00000002112.8
ENSMUST00000108455.1
Trappc6a

trafficking protein particle complex 6A

chr9_-_89705017 0.091 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr11_-_46166397 0.088 ENSMUST00000020679.2
Nipal4
NIPA-like domain containing 4
chr7_+_30650385 0.088 ENSMUST00000181529.1
Gm26610
predicted gene, 26610
chr13_+_94788873 0.088 ENSMUST00000046644.5
Tbca
tubulin cofactor A
chr11_+_109543694 0.085 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr17_+_28692568 0.084 ENSMUST00000114752.1
Mapk14
mitogen-activated protein kinase 14
chr14_-_57571551 0.082 ENSMUST00000022518.5
N6amt2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chrM_+_9870 0.082 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr17_+_78508063 0.080 ENSMUST00000024880.9
Vit
vitrin

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.6 2.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 2.1 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.4 2.0 GO:0021764 amygdala development(GO:0021764)
0.4 1.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.0 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.2 0.7 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 1.7 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 0.6 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 1.4 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.2 1.9 GO:0007379 segment specification(GO:0007379)
0.2 0.5 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.2 0.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.9 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.1 0.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 1.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.9 GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.1 0.6 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 1.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 1.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.1 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.1 0.3 GO:0072071 apoptotic process involved in heart morphogenesis(GO:0003278) regulation of vascular wound healing(GO:0061043) mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1 1.1 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.1 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.2 GO:0009812 flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.1 0.3 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.5 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.2 GO:0010985 negative regulation of lipoprotein particle clearance(GO:0010985)
0.1 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.7 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 1.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.3 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 2.5 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.1 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 0.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0010359 regulation of anion channel activity(GO:0010359)
0.0 0.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.0 0.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.0 GO:0035787 cell migration involved in kidney development(GO:0035787)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.1 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.0 0.0 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 1.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005584 collagen type I trimer(GO:0005584)
0.1 2.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.5 GO:0043205 fibril(GO:0043205)
0.1 1.2 GO:0042581 specific granule(GO:0042581)
0.1 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.7 GO:0097458 neuron part(GO:0097458)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.5 2.7 GO:0019841 retinol binding(GO:0019841)
0.3 1.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 1.4 GO:0015265 urea channel activity(GO:0015265)
0.2 0.9 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 0.7 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.5 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.1 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.3 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 5.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 2.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 1.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.0 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.0 GO:0071532 ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)