Motif ID: Ptf1a

Z-value: 0.450


Transcription factors associated with Ptf1a:

Gene SymbolEntrez IDGene Name
Ptf1a ENSMUSG00000026735.2 Ptf1a



Activity profile for motif Ptf1a.

activity profile for motif Ptf1a


Sorted Z-values histogram for motif Ptf1a

Sorted Z-values for motif Ptf1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Ptf1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_64046925 2.865 ENSMUST00000107377.3
 Tnc
tenascin C
chr7_-_79386943 2.798 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr11_+_78324200 1.862 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr16_+_91269759 1.185 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr9_-_112234956 1.065 ENSMUST00000162097.1
ENSMUST00000159055.1
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr9_-_112187766 0.936 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr19_+_7056731 0.747 ENSMUST00000040261.5
 Macrod1
MACRO domain containing 1
chr2_-_7396192 0.713 ENSMUST00000137733.2
 Celf2
CUGBP, Elav-like family member 2
chr5_-_99252839 0.684 ENSMUST00000168092.1
ENSMUST00000031276.8
 Rasgef1b

RasGEF domain family, member 1B

chr2_-_7395968 0.571 ENSMUST00000002176.6
 Celf2
CUGBP, Elav-like family member 2
chr1_-_16770138 0.568 ENSMUST00000071842.8
 Gm5828
predicted gene 5828
chr11_-_90390895 0.564 ENSMUST00000004051.7
 Hlf
hepatic leukemia factor
chr18_+_24709436 0.559 ENSMUST00000037097.7
 Fhod3
formin homology 2 domain containing 3
chr9_-_112187898 0.545 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chrX_+_166238923 0.527 ENSMUST00000060210.7
ENSMUST00000112233.1
 Gpm6b

glycoprotein m6b

chr15_+_80097866 0.502 ENSMUST00000143928.1
 Syngr1
synaptogyrin 1
chr4_-_155010984 0.498 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
 Plch2


phospholipase C, eta 2


chr15_+_31276491 0.417 ENSMUST00000068987.5
 Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chr8_-_105295934 0.403 ENSMUST00000057855.3
 Exoc3l
exocyst complex component 3-like
chr11_-_118355496 0.391 ENSMUST00000017610.3
 Timp2
tissue inhibitor of metalloproteinase 2
chr7_+_46396439 0.376 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr18_+_37477768 0.361 ENSMUST00000051442.5
 Pcdhb16
protocadherin beta 16
chr11_-_109611417 0.358 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
 Wipi1


WD repeat domain, phosphoinositide interacting 1


chr5_+_34525797 0.355 ENSMUST00000125817.1
ENSMUST00000067638.7
 Sh3bp2

SH3-domain binding protein 2

chr4_-_88438900 0.352 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
 Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr11_+_70017085 0.342 ENSMUST00000108589.2
 Dlg4
discs, large homolog 4 (Drosophila)
chr10_-_95417099 0.335 ENSMUST00000135822.1
 Socs2
suppressor of cytokine signaling 2
chr2_+_71981184 0.323 ENSMUST00000090826.5
ENSMUST00000102698.3
 Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr11_-_96916407 0.321 ENSMUST00000130774.1
 Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr9_+_106477269 0.313 ENSMUST00000047721.8
 Rrp9
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr2_-_91950386 0.302 ENSMUST00000111303.1
 Dgkz
diacylglycerol kinase zeta
chr3_+_75557530 0.297 ENSMUST00000161776.1
ENSMUST00000029423.8
 Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr2_-_118703963 0.288 ENSMUST00000104937.1
 Ankrd63
ankyrin repeat domain 63
chr2_+_164948219 0.268 ENSMUST00000017881.2
 Mmp9
matrix metallopeptidase 9
chr11_-_96916366 0.261 ENSMUST00000144731.1
ENSMUST00000127048.1
 Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr1_+_92910805 0.247 ENSMUST00000179711.1
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr5_+_64970069 0.246 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chr11_-_96916448 0.244 ENSMUST00000103152.4
 Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr19_+_9982694 0.237 ENSMUST00000025563.6
 Fth1
ferritin heavy chain 1
chr2_+_25500750 0.235 ENSMUST00000015239.3
 Fbxw5
F-box and WD-40 domain protein 5
chr14_-_70207637 0.232 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr5_+_134099704 0.231 ENSMUST00000016088.8
 Gatsl2
GATS protein-like 2
chr18_+_32377176 0.224 ENSMUST00000091967.5
ENSMUST00000025239.7
 Bin1

bridging integrator 1

chr2_-_30415302 0.221 ENSMUST00000132981.2
ENSMUST00000129494.1
 Crat

carnitine acetyltransferase

chr1_+_92910758 0.208 ENSMUST00000027487.8
 Rnpepl1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr11_+_19924403 0.204 ENSMUST00000093298.5
 Spred2
sprouty-related, EVH1 domain containing 2
chr4_+_152096719 0.196 ENSMUST00000105661.3
ENSMUST00000084115.3
 Plekhg5

pleckstrin homology domain containing, family G (with RhoGef domain) member 5

chr9_+_123021315 0.190 ENSMUST00000084733.5
 Tmem42
transmembrane protein 42
chr7_-_99182681 0.177 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr7_+_19131686 0.166 ENSMUST00000165913.1
 Fbxo46
F-box protein 46
chr10_+_86022189 0.166 ENSMUST00000120344.1
ENSMUST00000117597.1
 Fbxo7

F-box protein 7

chr7_-_79842287 0.162 ENSMUST00000049004.6
 Anpep
alanyl (membrane) aminopeptidase
chr11_-_100441058 0.150 ENSMUST00000107399.2
ENSMUST00000092688.5
 Nt5c3b

5'-nucleotidase, cytosolic IIIB

chr16_+_96145391 0.150 ENSMUST00000023913.8
ENSMUST00000135448.1
 Wrb

tryptophan rich basic protein

chr11_-_100441006 0.146 ENSMUST00000092689.2
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr10_+_69534039 0.135 ENSMUST00000182557.1
 Ank3
ankyrin 3, epithelial
chr8_+_94857450 0.110 ENSMUST00000109521.3
 Polr2c
polymerase (RNA) II (DNA directed) polypeptide C
chr7_-_25718976 0.109 ENSMUST00000002683.2
 Ccdc97
coiled-coil domain containing 97
chr11_+_49247462 0.104 ENSMUST00000109194.1
 Mgat1
mannoside acetylglucosaminyltransferase 1
chr14_+_75845093 0.097 ENSMUST00000110894.2
 Tpt1
tumor protein, translationally-controlled 1
chr11_-_6444352 0.094 ENSMUST00000093346.5
ENSMUST00000109737.2
 H2afv

H2A histone family, member V

chr10_+_86021961 0.093 ENSMUST00000130320.1
 Fbxo7
F-box protein 7
chr11_+_48800357 0.093 ENSMUST00000020640.7
 Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr7_-_144582392 0.092 ENSMUST00000033394.7
 Fadd
Fas (TNFRSF6)-associated via death domain
chr11_-_100440928 0.090 ENSMUST00000107397.1
 Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr10_+_90829538 0.088 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_+_26973416 0.087 ENSMUST00000014996.7
ENSMUST00000102891.3
 Adamts13

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

chrX_+_101383726 0.086 ENSMUST00000119190.1
 Gjb1
gap junction protein, beta 1
chr11_+_50131342 0.072 ENSMUST00000093138.6
ENSMUST00000101270.4
 Tbc1d9b

TBC1 domain family, member 9B

chr19_+_16435616 0.072 ENSMUST00000025602.2
 Gna14
guanine nucleotide binding protein, alpha 14
chr11_+_78465697 0.063 ENSMUST00000001126.3
 Slc46a1
solute carrier family 46, member 1
chr3_-_108445183 0.057 ENSMUST00000090553.5
ENSMUST00000153499.1
 Sars

seryl-aminoacyl-tRNA synthetase

chr15_-_79774383 0.054 ENSMUST00000069877.5
 Dnal4
dynein, axonemal, light chain 4
chr2_-_131175201 0.049 ENSMUST00000110218.2
 Spef1
sperm flagellar 1
chr17_+_7925990 0.041 ENSMUST00000036370.7
 Tagap
T cell activation Rho GTPase activating protein
chr11_+_120633719 0.023 ENSMUST00000181502.1
 Gm17586
predicted gene, 17586
chr4_-_36056726 0.021 ENSMUST00000108124.3
 Lingo2
leucine rich repeat and Ig domain containing 2
chr16_+_43762221 0.015 ENSMUST00000023390.4
 Drd3
dopamine receptor D3
chr10_+_42678890 0.014 ENSMUST00000040718.5
 Ostm1
osteopetrosis associated transmembrane protein 1
chr1_+_36691487 0.013 ENSMUST00000081180.4
 Cox5b
cytochrome c oxidase subunit Vb
chr15_-_79774408 0.009 ENSMUST00000023055.6
 Dnal4
dynein, axonemal, light chain 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 0.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 1.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.8 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122)
0.0 0.4 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 1.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.3 GO:2000821 synaptic vesicle maturation(GO:0016188) AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0097286 iron ion import(GO:0097286)
0.0 1.3 GO:0007601 visual perception(GO:0007601)
0.0 1.2 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0045545 syndecan binding(GO:0045545)
0.5 2.8 GO:0019841 retinol binding(GO:0019841)
0.3 1.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.7 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.1 0.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)