Motif ID: Rara

Z-value: 0.669


Transcription factors associated with Rara:

Gene SymbolEntrez IDGene Name
Rara ENSMUSG00000037992.10 Rara

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Raramm10_v2_chr11_+_98960412_989604850.432.7e-02Click!


Activity profile for motif Rara.

activity profile for motif Rara


Sorted Z-values histogram for motif Rara

Sorted Z-values for motif Rara



Network of associatons between targets according to the STRING database.



First level regulatory network of Rara

PNG image of the network

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Top targets:


Showing 1 to 20 of 66 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_94875600 3.987 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr10_+_4611971 2.498 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr4_-_46991842 1.568 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr5_-_114273702 1.320 ENSMUST00000144050.1
ENSMUST00000044790.5
 Foxn4

forkhead box N4

chr2_+_169633517 1.277 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chr4_-_141599835 1.254 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
 Fblim1



filamin binding LIM protein 1



chr11_+_98960412 1.192 ENSMUST00000107473.2
 Rara
retinoic acid receptor, alpha
chr5_+_135806859 1.147 ENSMUST00000126232.1
 Srrm3
serine/arginine repetitive matrix 3
chr17_-_56133817 1.132 ENSMUST00000167545.1
 Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr1_+_134037490 1.035 ENSMUST00000162779.1
 Fmod
fibromodulin
chr10_+_21993890 0.944 ENSMUST00000092673.4
 Sgk1
serum/glucocorticoid regulated kinase 1
chr3_-_36475688 0.813 ENSMUST00000029266.8
 Anxa5
annexin A5
chr14_-_16575456 0.805 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta
chr6_+_30723541 0.733 ENSMUST00000115127.1
 Mest
mesoderm specific transcript
chr17_+_34593388 0.646 ENSMUST00000174532.1
 Pbx2
pre B cell leukemia homeobox 2
chr4_-_152318458 0.625 ENSMUST00000170820.1
ENSMUST00000076183.5
 Rnf207

ring finger protein 207

chr7_-_141429351 0.578 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
 Cend1


cell cycle exit and neuronal differentiation 1


chr7_-_141429433 0.574 ENSMUST00000124444.1
 Cend1
cell cycle exit and neuronal differentiation 1
chr6_+_91157373 0.566 ENSMUST00000155007.1
 Hdac11
histone deacetylase 11
chr10_-_89257790 0.555 ENSMUST00000045601.7
 Ano4
anoctamin 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.6 2.5 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 1.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 1.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.4 1.2 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.0 1.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 1.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 0.8 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.7 GO:0010883 regulation of lipid storage(GO:0010883)
0.2 0.6 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 0.6 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 1.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 2.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 1.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.3 GO:0031005 filamin binding(GO:0031005)
0.1 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.7 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.1 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)