Motif ID: Rela_Rel_Nfkb1

Z-value: 1.546

Transcription factors associated with Rela_Rel_Nfkb1:

Gene SymbolEntrez IDGene Name
Nfkb1 ENSMUSG00000028163.11 Nfkb1
Rel ENSMUSG00000020275.8 Rel
Rela ENSMUSG00000024927.7 Rela

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfkb1mm10_v2_chr3_-_135691512_1356915640.891.2e-09Click!
Relamm10_v2_chr19_+_5637475_5637486-0.174.0e-01Click!


Activity profile for motif Rela_Rel_Nfkb1.

activity profile for motif Rela_Rel_Nfkb1


Sorted Z-values histogram for motif Rela_Rel_Nfkb1

Sorted Z-values for motif Rela_Rel_Nfkb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Rela_Rel_Nfkb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_165234689 12.557 ENSMUST00000065438.6
 Cdh22
cadherin 22
chr7_-_103843154 10.389 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr6_+_4755327 8.919 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr14_-_70642268 8.437 ENSMUST00000022697.5
 Fgf17
fibroblast growth factor 17
chr1_+_74791516 6.737 ENSMUST00000006718.8
 Wnt10a
wingless related MMTV integration site 10a
chr12_+_79029150 6.261 ENSMUST00000039928.5
 Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr7_-_25788635 6.227 ENSMUST00000002677.4
ENSMUST00000085948.4
 Axl

AXL receptor tyrosine kinase

chr3_+_7612702 6.134 ENSMUST00000181286.1
 Gm16685
predicted gene, 16685
chr8_-_61902669 5.583 ENSMUST00000121785.1
ENSMUST00000034057.7
 Palld

palladin, cytoskeletal associated protein

chr18_+_4994600 4.728 ENSMUST00000140448.1
 Svil
supervillin
chr2_-_156839790 4.448 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230


chr17_-_56005566 4.059 ENSMUST00000043785.6
 Stap2
signal transducing adaptor family member 2
chr1_+_64532790 4.027 ENSMUST00000049932.5
ENSMUST00000087366.4
ENSMUST00000171164.1
 Creb1


cAMP responsive element binding protein 1


chr3_+_14641722 3.889 ENSMUST00000029071.8
 Car13
carbonic anhydrase 13
chr3_-_135691512 3.841 ENSMUST00000029812.7
 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr6_+_134035691 3.794 ENSMUST00000081028.6
ENSMUST00000111963.1
 Etv6

ets variant gene 6 (TEL oncogene)

chr4_+_124986430 3.574 ENSMUST00000030687.7
 Rspo1
R-spondin homolog (Xenopus laevis)
chr14_-_48662740 3.479 ENSMUST00000122009.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr5_+_92925400 3.367 ENSMUST00000172706.1
 Shroom3
shroom family member 3
chr6_+_48841476 3.337 ENSMUST00000101426.4
 Tmem176a
transmembrane protein 176A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 238 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 10.4 GO:0015671 oxygen transport(GO:0015671)
1.4 10.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.5 9.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.9 8.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 8.5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 7.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.7 6.7 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.6 6.7 GO:0048733 sebaceous gland development(GO:0048733)
1.0 6.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.2 6.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.8 5.6 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.4 5.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.5 4.6 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.8 4.6 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.9 4.5 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 4.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 4.2 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 4.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.6 4.1 GO:0007296 vitellogenesis(GO:0007296)
1.3 4.0 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 10.4 GO:0005833 hemoglobin complex(GO:0005833)
0.1 8.4 GO:0031225 anchored component of membrane(GO:0031225)
1.1 7.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 7.6 GO:0000922 spindle pole(GO:0000922)
0.5 7.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.5 6.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 6.4 GO:0043034 costamere(GO:0043034)
0.3 5.9 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 5.1 GO:0034707 chloride channel complex(GO:0034707)
0.2 4.8 GO:0002102 podosome(GO:0002102)
0.0 4.6 GO:0005925 focal adhesion(GO:0005925)
0.6 4.5 GO:0098536 deuterosome(GO:0098536)
0.1 4.5 GO:0005882 intermediate filament(GO:0005882)
0.4 4.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 4.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 4.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 3.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.7 3.5 GO:0031523 Myb complex(GO:0031523)
0.1 3.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.1 GO:0043296 apical junction complex(GO:0043296)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 20.6 GO:0044822 poly(A) RNA binding(GO:0044822)
0.0 12.8 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1 12.7 GO:0005178 integrin binding(GO:0005178)
2.6 10.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 8.8 GO:0051015 actin filament binding(GO:0051015)
0.7 8.5 GO:0031996 thioesterase binding(GO:0031996)
2.8 8.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 7.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 7.4 GO:0005109 frizzled binding(GO:0005109)
0.2 7.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 6.9 GO:0005509 calcium ion binding(GO:0005509)
0.5 6.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.6 6.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 4.7 GO:0042805 actinin binding(GO:0042805)
0.3 4.6 GO:0019215 intermediate filament binding(GO:0019215)
0.2 4.6 GO:0070410 co-SMAD binding(GO:0070410)
0.3 4.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 4.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 4.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 3.9 GO:0004089 carbonate dehydratase activity(GO:0004089)