Motif ID: Relb

Z-value: 0.650


Transcription factors associated with Relb:

Gene SymbolEntrez IDGene Name
Relb ENSMUSG00000002983.10 Relb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Relbmm10_v2_chr7_-_19629355_196294510.423.1e-02Click!


Activity profile for motif Relb.

activity profile for motif Relb


Sorted Z-values histogram for motif Relb

Sorted Z-values for motif Relb



Network of associatons between targets according to the STRING database.



First level regulatory network of Relb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_8940977 3.899 ENSMUST00000071184.2
 Rpl10a-ps2
ribosomal protein L10A, pseudogene 2
chr2_-_5714490 3.846 ENSMUST00000044009.7
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr1_-_45890078 3.764 ENSMUST00000183590.1
 Gm5269
predicted gene 5269
chr15_-_79164477 2.406 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chr14_+_80000292 2.002 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr7_+_99535652 1.918 ENSMUST00000032995.8
ENSMUST00000162404.1
 Arrb1

arrestin, beta 1

chr2_-_5063996 1.848 ENSMUST00000114996.1
 Optn
optineurin
chr7_+_99535439 1.792 ENSMUST00000098266.2
ENSMUST00000179755.1
 Arrb1

arrestin, beta 1

chr9_+_64385626 1.719 ENSMUST00000093829.2
ENSMUST00000118485.1
ENSMUST00000164113.1
 Megf11


multiple EGF-like-domains 11


chr2_-_5063932 1.662 ENSMUST00000027986.4
 Optn
optineurin
chr4_+_130915949 1.653 ENSMUST00000030316.6
 Laptm5
lysosomal-associated protein transmembrane 5
chr5_+_90891234 1.462 ENSMUST00000031327.8
 Cxcl1
chemokine (C-X-C motif) ligand 1
chr3_-_9610074 1.248 ENSMUST00000041124.7
 Zfp704
zinc finger protein 704
chr4_+_129985098 1.226 ENSMUST00000106017.1
ENSMUST00000121049.1
 Bai2

brain-specific angiogenesis inhibitor 2

chr9_+_64385675 1.219 ENSMUST00000068967.4
 Megf11
multiple EGF-like-domains 11
chrX_+_163908982 1.153 ENSMUST00000069041.8
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr18_+_37484955 1.120 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr8_+_72319033 1.089 ENSMUST00000067912.7
 Klf2
Kruppel-like factor 2 (lung)
chr5_+_150259922 1.054 ENSMUST00000087204.5
 Fry
furry homolog (Drosophila)
chrX_+_163909132 0.986 ENSMUST00000033734.7
ENSMUST00000112294.2
 Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr3_-_107760221 0.971 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
 Csf1


colony stimulating factor 1 (macrophage)


chr11_+_90030295 0.969 ENSMUST00000092788.3
 Tmem100
transmembrane protein 100
chr1_+_152399824 0.918 ENSMUST00000044311.8
 Colgalt2
collagen beta(1-O)galactosyltransferase 2
chr4_+_129984833 0.899 ENSMUST00000120204.1
 Bai2
brain-specific angiogenesis inhibitor 2
chr7_-_28766469 0.814 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr12_+_102948843 0.805 ENSMUST00000101099.5
 Unc79
unc-79 homolog (C. elegans)
chr6_-_124741374 0.784 ENSMUST00000004389.5
 Grcc10
gene rich cluster, C10 gene
chr15_-_98677451 0.783 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
 Rnd1


Rho family GTPase 1


chr7_+_28766747 0.779 ENSMUST00000170068.1
ENSMUST00000072965.4
 Sirt2

sirtuin 2

chr2_+_10153563 0.777 ENSMUST00000026886.7
 Itih5
inter-alpha (globulin) inhibitor H5
chr12_-_55492587 0.740 ENSMUST00000021413.7
 Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr1_+_15287259 0.738 ENSMUST00000175681.1
 Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr15_-_33405976 0.709 ENSMUST00000079057.6
 1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr14_+_55560480 0.707 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
 Dcaf11


DDB1 and CUL4 associated factor 11


chr4_-_101265236 0.672 ENSMUST00000149297.1
ENSMUST00000102781.3
 Jak1

Janus kinase 1

chr7_+_16309577 0.664 ENSMUST00000002152.6
 Bbc3
BCL2 binding component 3
chr7_-_19629355 0.662 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
 Relb


avian reticuloendotheliosis viral (v-rel) oncogene related B


chr7_+_43463145 0.657 ENSMUST00000107977.1
 Vsig10l
ZV-set and immunoglobulin domain containing 10 like
chr10_-_19015347 0.602 ENSMUST00000019997.4
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chrX_+_36112110 0.583 ENSMUST00000033418.7
 Il13ra1
interleukin 13 receptor, alpha 1
chr10_-_93310963 0.560 ENSMUST00000151153.1
 Elk3
ELK3, member of ETS oncogene family
chr15_-_89429093 0.434 ENSMUST00000170460.1
 Chkb
choline kinase beta
chr4_+_126262325 0.415 ENSMUST00000030660.8
 Trappc3
trafficking protein particle complex 3
chr4_-_40239779 0.401 ENSMUST00000037907.6
 Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_-_27027909 0.377 ENSMUST00000102890.4
ENSMUST00000153388.1
ENSMUST00000045702.5
 Slc2a6


solute carrier family 2 (facilitated glucose transporter), member 6


chr10_-_93311073 0.366 ENSMUST00000008542.5
 Elk3
ELK3, member of ETS oncogene family
chr2_+_18672384 0.365 ENSMUST00000171845.1
ENSMUST00000061158.4
 Commd3

COMM domain containing 3

chr5_-_122989260 0.348 ENSMUST00000118027.1
 Kdm2b
lysine (K)-specific demethylase 2B
chr7_-_45920830 0.331 ENSMUST00000164119.1
 Emp3
epithelial membrane protein 3
chr4_+_43631935 0.330 ENSMUST00000030191.8
 Npr2
natriuretic peptide receptor 2
chr5_-_122989086 0.330 ENSMUST00000046073.9
 Kdm2b
lysine (K)-specific demethylase 2B
chr16_-_55838827 0.329 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
 Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr4_+_114680769 0.291 ENSMUST00000146346.1
 Gm12829
predicted gene 12829
chr2_+_119972699 0.248 ENSMUST00000066058.7
 Mapkbp1
mitogen-activated protein kinase binding protein 1
chr15_-_89170688 0.202 ENSMUST00000060808.9
 Plxnb2
plexin B2
chr13_+_83732438 0.174 ENSMUST00000182701.1
 C130071C03Rik
RIKEN cDNA C130071C03 gene
chr4_-_40239700 0.166 ENSMUST00000142055.1
 Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr11_-_54956047 0.156 ENSMUST00000155316.1
ENSMUST00000108889.3
ENSMUST00000126703.1
 Tnip1


TNFAIP3 interacting protein 1


chr7_-_99626936 0.141 ENSMUST00000178124.1
 Gm4980
predicted gene 4980
chr12_-_54862783 0.123 ENSMUST00000078124.7
 Cfl2
cofilin 2, muscle
chr10_+_111125851 0.076 ENSMUST00000171120.1
 Gm5428
predicted gene 5428
chr18_+_36559972 0.072 ENSMUST00000134146.1
 Ankhd1
ankyrin repeat and KH domain containing 1
chr4_-_91399984 0.070 ENSMUST00000102799.3
 Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr10_+_96616998 0.047 ENSMUST00000038377.7
 Btg1
B cell translocation gene 1, anti-proliferative
chr12_+_111538101 0.023 ENSMUST00000166123.1
 Eif5
eukaryotic translation initiation factor 5
chr10_-_77902467 0.018 ENSMUST00000057608.4
 Lrrc3
leucine rich repeat containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.5 3.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.5 3.7 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 1.0 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.3 1.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2 1.5 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.2 2.4 GO:0048484 enteric nervous system development(GO:0048484)
0.2 0.8 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.2 1.1 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.2 0.7 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.2 0.7 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 0.8 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 0.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 1.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 1.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 2.9 GO:0010842 retina layer formation(GO:0010842)
0.1 0.8 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.8 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.4 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 2.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 2.1 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.7 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.1 GO:0030836 positive regulation of actin filament depolymerization(GO:0030836)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 2.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 3.7 GO:0031143 pseudopodium(GO:0031143)
0.1 2.0 GO:0042581 specific granule(GO:0042581)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 3.5 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.4 3.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 0.4 GO:0004103 choline kinase activity(GO:0004103)
0.1 3.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.7 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 2.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 2.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 2.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.0 GO:0005125 cytokine activity(GO:0005125)