Motif ID: Rfx2_Rfx7

Z-value: 1.414

Transcription factors associated with Rfx2_Rfx7:

Gene SymbolEntrez IDGene Name
Rfx2 ENSMUSG00000024206.8 Rfx2
Rfx7 ENSMUSG00000037674.9 Rfx7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx2mm10_v2_chr17_-_56830916_56831008-0.096.6e-01Click!
Rfx7mm10_v2_chr9_+_72532609_72532828-0.096.7e-01Click!


Activity profile for motif Rfx2_Rfx7.

activity profile for motif Rfx2_Rfx7


Sorted Z-values histogram for motif Rfx2_Rfx7

Sorted Z-values for motif Rfx2_Rfx7



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx2_Rfx7

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_129960760 3.012 ENSMUST00000139884.1
 1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr7_+_44468051 2.789 ENSMUST00000118493.1
 Josd2
Josephin domain containing 2
chr2_-_21205342 2.301 ENSMUST00000027992.2
 Enkur
enkurin, TRPC channel interacting protein
chr3_+_156562141 2.301 ENSMUST00000175773.1
 Negr1
neuronal growth regulator 1
chr1_+_43730593 2.205 ENSMUST00000027217.8
 1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr3_+_156561792 1.984 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr7_+_27233003 1.913 ENSMUST00000003860.6
ENSMUST00000108378.3
 Adck4

aarF domain containing kinase 4

chr7_+_44468020 1.782 ENSMUST00000117324.1
ENSMUST00000120852.1
ENSMUST00000118628.1
 Josd2


Josephin domain containing 2


chr5_+_27261916 1.769 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr17_-_10840285 1.724 ENSMUST00000041463.6
 Pacrg
PARK2 co-regulated
chr18_+_75820174 1.724 ENSMUST00000058997.7
 Zbtb7c
zinc finger and BTB domain containing 7C
chr2_-_144527341 1.677 ENSMUST00000163701.1
ENSMUST00000081982.5
 Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr12_+_105336922 1.617 ENSMUST00000180503.1
 2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr9_-_53975246 1.616 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chr10_+_79669410 1.604 ENSMUST00000020552.5
 Tpgs1
tubulin polyglutamylase complex subunit 1
chr17_+_68837062 1.585 ENSMUST00000178545.1
 Tmem200c
transmembrane protein 200C
chr3_+_156561950 1.549 ENSMUST00000041425.5
ENSMUST00000106065.1
 Negr1

neuronal growth regulator 1

chr12_-_110840905 1.527 ENSMUST00000177224.1
ENSMUST00000084974.4
ENSMUST00000070565.8
 Stk30


serine/threonine kinase 30


chr7_+_16959714 1.475 ENSMUST00000038163.6
 Pnmal1
PNMA-like 1
chr6_+_135362931 1.456 ENSMUST00000032330.9
 Emp1
epithelial membrane protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 131 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 5.2 GO:0007631 feeding behavior(GO:0007631)
0.8 4.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.4 3.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.3 2.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 1.9 GO:0007520 myoblast fusion(GO:0007520)
0.4 1.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.8 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.2 1.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 1.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.7 GO:0000423 macromitophagy(GO:0000423)
0.2 1.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.6 GO:0007288 sperm axoneme assembly(GO:0007288)
0.4 1.5 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.5 GO:0032060 bleb assembly(GO:0032060)
0.3 1.4 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.0 1.4 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 1.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3 1.3 GO:0018307 enzyme active site formation(GO:0018307)
0.1 1.3 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.7 GO:0031225 anchored component of membrane(GO:0031225)
0.3 4.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 3.8 GO:0097228 sperm principal piece(GO:0097228)
0.2 2.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.1 GO:0031514 motile cilium(GO:0031514)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.8 GO:0031045 dense core granule(GO:0031045)
0.1 1.7 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 1.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 1.5 GO:0036157 axonemal dynein complex(GO:0005858) outer dynein arm(GO:0036157)
0.0 1.5 GO:0042641 actomyosin(GO:0042641)
0.1 1.4 GO:0005605 basal lamina(GO:0005605)
0.2 1.3 GO:0000235 astral microtubule(GO:0000235)
0.0 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.2 GO:0071565 nBAF complex(GO:0071565)
0.3 1.0 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.0 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.9 GO:0008242 omega peptidase activity(GO:0008242)
0.5 4.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.0 3.2 GO:0030276 clathrin binding(GO:0030276)
0.0 2.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.7 GO:0008017 microtubule binding(GO:0008017)
0.0 2.3 GO:0003774 motor activity(GO:0003774)
0.1 2.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.9 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 1.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.3 1.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 1.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 1.4 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 1.4 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.3 1.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.4 1.1 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 1.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.0 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)