Motif ID: Rfx5

Z-value: 0.705


Transcription factors associated with Rfx5:

Gene SymbolEntrez IDGene Name
Rfx5 ENSMUSG00000005774.6 Rfx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx5mm10_v2_chr3_+_94954075_949542260.077.4e-01Click!


Activity profile for motif Rfx5.

activity profile for motif Rfx5


Sorted Z-values histogram for motif Rfx5

Sorted Z-values for motif Rfx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx5

PNG image of the network

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Top targets:


Showing 1 to 20 of 62 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_37376359 2.014 ENSMUST00000012587.3
 Kif11
kinesin family member 11
chr17_+_34263209 1.958 ENSMUST00000040828.5
 H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr7_+_46841475 1.901 ENSMUST00000147535.1
 Ldha
lactate dehydrogenase A
chr17_+_35861318 1.883 ENSMUST00000074259.8
ENSMUST00000174873.1
 Nrm

nurim (nuclear envelope membrane protein)

chr7_-_30664986 1.765 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chr7_-_105752193 1.556 ENSMUST00000033184.4
 Tpp1
tripeptidyl peptidase I
chr17_+_35861343 1.550 ENSMUST00000172931.1
 Nrm
nurim (nuclear envelope membrane protein)
chr17_+_35439155 1.448 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
 H2-Q7



histocompatibility 2, Q region locus 7



chr4_-_116627921 1.406 ENSMUST00000030456.7
 Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr1_-_183147461 1.365 ENSMUST00000171366.1
 Disp1
dispatched homolog 1 (Drosophila)
chr17_+_37270214 1.288 ENSMUST00000038580.6
 H2-M3
histocompatibility 2, M region locus 3
chr8_+_94214567 1.220 ENSMUST00000079961.6
 Nup93
nucleoporin 93
chr2_+_122147680 1.062 ENSMUST00000102476.4
 B2m
beta-2 microglobulin
chr11_+_117523526 1.007 ENSMUST00000132261.1
 Gm11734
predicted gene 11734
chr17_+_34398802 0.969 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
 BC051142



cDNA sequence BC051142



chr12_+_108334341 0.929 ENSMUST00000021684.4
 Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr11_-_3539228 0.929 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
 Smtn



smoothelin



chr7_-_45092130 0.910 ENSMUST00000148175.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr11_+_61505138 0.893 ENSMUST00000102657.3
 B9d1
B9 protein domain 1
chr7_-_45091713 0.808 ENSMUST00000141576.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.0 GO:0002339 B cell selection(GO:0002339)
0.3 2.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.4 1.9 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 1.8 GO:0051225 spindle assembly(GO:0051225)
0.1 1.6 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.4 GO:0060539 diaphragm development(GO:0060539)
0.1 1.4 GO:0043486 histone exchange(GO:0043486)
0.4 1.3 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.1 1.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 1.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 1.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.9 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.7 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.1 0.6 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.3 GO:0042611 MHC protein complex(GO:0042611)
0.2 3.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 2.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.8 GO:0070652 HAUS complex(GO:0070652)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 0.5 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.5 GO:0046977 TAP binding(GO:0046977)
0.2 2.0 GO:0015643 toxic substance binding(GO:0015643)
0.5 1.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 1.6 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 0.9 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.7 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.7 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)