Motif ID: Rorc_Nr1d1

Z-value: 0.779

Transcription factors associated with Rorc_Nr1d1:

Gene SymbolEntrez IDGene Name
Nr1d1 ENSMUSG00000020889.11 Nr1d1
Rorc ENSMUSG00000028150.8 Rorc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1d1mm10_v2_chr11_-_98775333_987753540.404.1e-02Click!
Rorcmm10_v2_chr3_+_94377432_943774510.232.7e-01Click!


Activity profile for motif Rorc_Nr1d1.

activity profile for motif Rorc_Nr1d1


Sorted Z-values histogram for motif Rorc_Nr1d1

Sorted Z-values for motif Rorc_Nr1d1



Network of associatons between targets according to the STRING database.



First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Top targets:


Showing 1 to 20 of 109 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_42520325 5.087 ENSMUST00000104977.2
 Gm4877
predicted gene 4877
chr11_+_98348404 4.761 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_79386943 3.809 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr11_-_98329641 3.151 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr15_-_66801577 2.757 ENSMUST00000168589.1
 Sla
src-like adaptor
chr2_+_90885860 2.681 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr19_+_26623419 2.049 ENSMUST00000176584.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_52490736 1.662 ENSMUST00000170269.1
 Nab1
Ngfi-A binding protein 1
chr12_-_24493656 1.528 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr9_-_75441652 1.493 ENSMUST00000181896.1
 A130057D12Rik
RIKEN cDNA A130057D12 gene
chr1_-_14310198 1.452 ENSMUST00000168081.2
ENSMUST00000027066.6
 Eya1

eyes absent 1 homolog (Drosophila)

chr7_+_45705088 1.185 ENSMUST00000080885.3
 Dbp
D site albumin promoter binding protein
chr3_-_101307079 1.159 ENSMUST00000097146.2
 Gm10355
predicted gene 10355
chr3_-_89764581 1.148 ENSMUST00000029562.3
 Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr11_-_84069179 1.105 ENSMUST00000138208.1
 Dusp14
dual specificity phosphatase 14
chr10_+_106470281 1.058 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr9_-_48911067 1.046 ENSMUST00000003826.7
 Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr6_+_61180313 0.910 ENSMUST00000126214.1
 Ccser1
coiled-coil serine rich 1
chr4_-_33189410 0.894 ENSMUST00000098181.2
 Pm20d2
peptidase M20 domain containing 2
chr2_-_5676046 0.833 ENSMUST00000114987.3
 Camk1d
calcium/calmodulin-dependent protein kinase ID

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 4.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 3.9 GO:0007601 visual perception(GO:0007601)
1.1 3.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 2.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 1.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 1.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.4 1.1 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.1 1.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.3 1.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.3 0.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.4 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.0 0.4 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.2 GO:0044297 cell body(GO:0044297)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.8 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 4.8 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.6 3.8 GO:0019841 retinol binding(GO:0019841)
0.1 3.2 GO:0070888 E-box binding(GO:0070888)
0.0 3.1 GO:0005125 cytokine activity(GO:0005125)
0.1 2.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.1 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.2 0.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.5 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)