Motif ID: Rorc_Nr1d1

Z-value: 0.779

Transcription factors associated with Rorc_Nr1d1:

Gene SymbolEntrez IDGene Name
Nr1d1 ENSMUSG00000020889.11 Nr1d1
Rorc ENSMUSG00000028150.8 Rorc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1d1mm10_v2_chr11_-_98775333_987753540.404.1e-02Click!
Rorcmm10_v2_chr3_+_94377432_943774510.232.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_42520325 5.087 ENSMUST00000104977.2
Gm4877
predicted gene 4877
chr11_+_98348404 4.761 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_79386943 3.809 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr11_-_98329641 3.151 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr15_-_66801577 2.757 ENSMUST00000168589.1
Sla
src-like adaptor
chr2_+_90885860 2.681 ENSMUST00000111466.2
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr19_+_26623419 2.049 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_52490736 1.662 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chr12_-_24493656 1.528 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr9_-_75441652 1.493 ENSMUST00000181896.1
A130057D12Rik
RIKEN cDNA A130057D12 gene
chr1_-_14310198 1.452 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr7_+_45705088 1.185 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr3_-_101307079 1.159 ENSMUST00000097146.2
Gm10355
predicted gene 10355
chr3_-_89764581 1.148 ENSMUST00000029562.3
Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr11_-_84069179 1.105 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr10_+_106470281 1.058 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr9_-_48911067 1.046 ENSMUST00000003826.7
Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr6_+_61180313 0.910 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr4_-_33189410 0.894 ENSMUST00000098181.2
Pm20d2
peptidase M20 domain containing 2
chr2_-_5676046 0.833 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr1_+_23761749 0.830 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr7_+_113207465 0.759 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr11_-_115628260 0.728 ENSMUST00000178003.1
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr3_-_84304762 0.721 ENSMUST00000107692.1
Trim2
tripartite motif-containing 2
chr6_-_88874045 0.649 ENSMUST00000038409.5
Podxl2
podocalyxin-like 2
chr1_-_180193475 0.644 ENSMUST00000160482.1
ENSMUST00000170472.1
Adck3

aarF domain containing kinase 3

chrX_-_143933204 0.583 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr5_+_64803513 0.581 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chrX_-_143933089 0.559 ENSMUST00000087313.3
Dcx
doublecortin
chr17_-_56133817 0.497 ENSMUST00000167545.1
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr12_-_34528844 0.495 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chrX_-_16911774 0.483 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr5_+_64970069 0.469 ENSMUST00000031080.8
Fam114a1
family with sequence similarity 114, member A1
chr11_+_70030023 0.446 ENSMUST00000143920.2
Dlg4
discs, large homolog 4 (Drosophila)
chr17_+_37046555 0.424 ENSMUST00000172789.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_-_134232125 0.403 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chrX_-_136203637 0.399 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
Tceal5


transcription elongation factor A (SII)-like 5


chrX_+_103422010 0.388 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr12_-_72408934 0.380 ENSMUST00000078505.7
Rtn1
reticulon 1
chr4_+_98546919 0.331 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr2_-_170427828 0.330 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr8_+_119862239 0.319 ENSMUST00000034287.8
Klhl36
kelch-like 36
chr2_+_4389614 0.313 ENSMUST00000115037.2
Frmd4a
FERM domain containing 4A
chr3_+_79884576 0.312 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr14_+_118787894 0.302 ENSMUST00000047761.6
ENSMUST00000071546.7
Cldn10

claudin 10

chr9_-_101034857 0.299 ENSMUST00000142676.1
ENSMUST00000149322.1
Pccb

propionyl Coenzyme A carboxylase, beta polypeptide

chr5_-_122779278 0.293 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr11_+_95712673 0.291 ENSMUST00000107717.1
Zfp652
zinc finger protein 652
chr14_-_36935560 0.281 ENSMUST00000183038.1
Ccser2
coiled-coil serine rich 2
chr10_+_57784859 0.271 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr14_+_27622433 0.265 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr13_-_52981027 0.262 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr1_-_191907527 0.254 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr3_-_153944425 0.247 ENSMUST00000150070.1
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr12_-_84876479 0.245 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
Ltbp2


latent transforming growth factor beta binding protein 2


chr1_-_162478004 0.245 ENSMUST00000086074.5
ENSMUST00000070330.7
Dnm3

dynamin 3

chrX_+_42151002 0.241 ENSMUST00000123245.1
Stag2
stromal antigen 2
chrX_+_70385870 0.229 ENSMUST00000053981.5
1110012L19Rik
RIKEN cDNA 1110012L19 gene
chr9_-_54647199 0.225 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr10_+_73821857 0.220 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr15_+_81872309 0.217 ENSMUST00000023116.6
Aco2
aconitase 2, mitochondrial
chr11_-_116198701 0.215 ENSMUST00000072948.4
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr5_-_115484297 0.212 ENSMUST00000112067.1
Sirt4
sirtuin 4
chr9_-_101034892 0.209 ENSMUST00000035116.5
Pccb
propionyl Coenzyme A carboxylase, beta polypeptide
chr1_+_143739551 0.186 ENSMUST00000050491.9
Glrx2
glutaredoxin 2 (thioltransferase)
chr11_-_116199040 0.182 ENSMUST00000066587.5
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr5_+_144100387 0.173 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr17_-_46032366 0.165 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A


chr11_+_116198853 0.157 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr2_-_91710519 0.155 ENSMUST00000028678.8
ENSMUST00000076803.5
Atg13

autophagy related 13

chr2_+_61593077 0.153 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank

TRAF family member-associated Nf-kappa B activator

chr7_+_45627482 0.153 ENSMUST00000057927.7
Rasip1
Ras interacting protein 1
chr15_+_89253035 0.145 ENSMUST00000088788.3
Ppp6r2
protein phosphatase 6, regulatory subunit 2
chr2_+_61593125 0.143 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chr13_+_21495218 0.142 ENSMUST00000104942.1
AK157302
cDNA sequence AK157302
chr4_+_54945038 0.134 ENSMUST00000133895.1
Zfp462
zinc finger protein 462
chr11_-_51635870 0.132 ENSMUST00000001081.3
Rmnd5b
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr9_-_106447584 0.128 ENSMUST00000171678.1
ENSMUST00000048685.6
ENSMUST00000171925.1
Abhd14a


abhydrolase domain containing 14A


chr2_-_153015331 0.127 ENSMUST00000028972.8
Pdrg1
p53 and DNA damage regulated 1
chr19_+_6384395 0.118 ENSMUST00000035269.8
ENSMUST00000113483.1
Pygm

muscle glycogen phosphorylase

chr17_-_51810866 0.117 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr17_-_45686899 0.117 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr3_+_90603767 0.116 ENSMUST00000001046.5
ENSMUST00000107330.1
S100a4

S100 calcium binding protein A4

chr12_-_54695829 0.101 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
Eapp



E2F-associated phosphoprotein



chr11_-_51688614 0.093 ENSMUST00000007921.2
0610009B22Rik
RIKEN cDNA 0610009B22 gene
chr7_-_134232005 0.085 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr5_-_123141067 0.083 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr10_+_39612934 0.078 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr9_+_65460926 0.073 ENSMUST00000034955.6
Spg21
spastic paraplegia 21 homolog (human)
chr6_+_134830145 0.071 ENSMUST00000046303.5
Crebl2
cAMP responsive element binding protein-like 2
chr16_-_21995478 0.069 ENSMUST00000074230.4
ENSMUST00000060673.6
Liph

lipase, member H

chr5_+_145084100 0.058 ENSMUST00000124379.1
Arpc1a
actin related protein 2/3 complex, subunit 1A
chr6_-_93913678 0.054 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr17_+_24896488 0.048 ENSMUST00000024978.6
Nme3
NME/NM23 nucleoside diphosphate kinase 3
chr9_+_54863742 0.039 ENSMUST00000034843.7
Ireb2
iron responsive element binding protein 2
chr1_+_171895664 0.036 ENSMUST00000097466.2
Gm10521
predicted gene 10521
chr14_+_73142490 0.036 ENSMUST00000170370.1
ENSMUST00000164822.1
ENSMUST00000165429.1
Rcbtb2


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2


chr8_-_85080652 0.030 ENSMUST00000152785.1
Wdr83
WD repeat domain containing 83
chr13_+_52596847 0.028 ENSMUST00000055087.6
Syk
spleen tyrosine kinase
chr6_-_124712131 0.025 ENSMUST00000004379.5
Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr6_+_29361410 0.021 ENSMUST00000156163.1
Calu
calumenin
chr3_+_53463666 0.020 ENSMUST00000058577.4
Proser1
proline and serine rich 1
chr17_-_46031813 0.019 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr1_+_160195215 0.019 ENSMUST00000135680.1
ENSMUST00000097193.2
Mrps14

mitochondrial ribosomal protein S14

chr7_-_30559600 0.015 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr7_-_142661305 0.012 ENSMUST00000105936.1
Igf2
insulin-like growth factor 2
chr2_+_91710852 0.010 ENSMUST00000128140.1
ENSMUST00000140183.1
Harbi1

harbinger transposase derived 1

chr17_-_34628380 0.007 ENSMUST00000167097.2
Ppt2
palmitoyl-protein thioesterase 2
chr7_+_46033698 0.003 ENSMUST00000033121.6
Nomo1
nodal modulator 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.1 3.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 1.1 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.3 1.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.3 0.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 1.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 2.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 1.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.2 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.1 0.4 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.0 1.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 3.9 GO:0007601 visual perception(GO:0007601)
0.0 0.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 1.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.4 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.2 GO:0043206 extracellular fibril organization(GO:0043206)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.8 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 10.2 GO:0044297 cell body(GO:0044297)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.6 3.8 GO:0019841 retinol binding(GO:0019841)
0.3 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.2 0.5 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.2 0.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 3.2 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 2.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.0 0.2 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 3.1 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0043531 ADP binding(GO:0043531)