Motif ID: Runx3

Z-value: 0.729


Transcription factors associated with Runx3:

Gene SymbolEntrez IDGene Name
Runx3 ENSMUSG00000070691.4 Runx3



Activity profile for motif Runx3.

activity profile for motif Runx3


Sorted Z-values histogram for motif Runx3

Sorted Z-values for motif Runx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Runx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 79 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_20181773 3.551 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr13_-_22041352 2.291 ENSMUST00000102977.2
Hist1h4i
histone cluster 1, H4i
chr3_-_154330543 1.961 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr13_-_23551648 1.645 ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chr17_+_27556613 1.324 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1

high mobility group AT-hook 1

chr17_+_27556668 1.311 ENSMUST00000117254.1
ENSMUST00000118570.1
Hmga1

high mobility group AT-hook 1

chr13_-_23698454 1.309 ENSMUST00000102967.1
Hist1h4c
histone cluster 1, H4c
chr17_+_27556641 1.294 ENSMUST00000119486.1
ENSMUST00000118599.1
Hmga1

high mobility group AT-hook 1

chr7_+_141216626 1.285 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr18_-_47368446 1.246 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr13_-_21832194 1.213 ENSMUST00000102979.1
Hist1h4n
histone cluster 1, H4n
chr18_-_77713978 1.166 ENSMUST00000074653.4
8030462N17Rik
RIKEN cDNA 8030462N17 gene
chr11_-_89302545 1.157 ENSMUST00000061728.3
Nog
noggin
chr15_+_40655020 1.112 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr13_+_51645232 1.009 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chrX_+_99136119 0.938 ENSMUST00000052839.6
Efnb1
ephrin B1
chr7_-_78783026 0.907 ENSMUST00000032841.5
Mrpl46
mitochondrial ribosomal protein L46
chr13_+_21735055 0.856 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr13_+_37826225 0.848 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr11_-_5878207 0.821 ENSMUST00000102922.3
Pold2
polymerase (DNA directed), delta 2, regulatory subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.8 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 3.9 GO:0006284 base-excision repair(GO:0006284)
0.3 2.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.0 GO:0021884 forebrain neuron development(GO:0021884)
0.1 1.8 GO:0060009 Sertoli cell development(GO:0060009)
0.3 1.2 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 1.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.4 1.1 GO:0003195 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 1.0 GO:0007127 meiosis I(GO:0007127)
0.0 0.9 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 0.7 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.7 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.7 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.2 0.6 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.1 0.6 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.6 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.8 GO:0000786 nucleosome(GO:0000786)
0.6 3.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 2.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 0.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.5 GO:0042393 histone binding(GO:0042393)
0.4 3.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 2.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0019955 cytokine binding(GO:0019955)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.5 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)